Clinical Trial News and Research

RSS

Collaborative study investigates underlying cause of neuropsychiatric symptoms in Parkinson's disease

Parkinson's disease is most known for its movement-related symptoms: tremors and rigidity, slowness and falls, caused by the loss of the brain's dopamine-producing neurons.

4 Oct 2024

New strategy uses bacteriophages to combat drug-resistant infections

Researchers have a new battle tactic to fight drug-resistant bacterial infections. Their strategy involves using collections of bacteriophages, viruses that naturally attack bacteria.

4 Oct 2024

Imagery rescripting offers new hope for treating hoarding disorder

Rehearsing alternative outcomes of discarding through imagery rescripting shows promise as a treatment strategy for people who hoard, a study by UNSW psychology researchers has shown.

4 Oct 2024

Thousands could have been saved during the pandemic with expanded use of convalescent plasma

A new study led by researchers at Johns Hopkins Bloomberg School of Public Health estimates that thousands of lives could have been saved during the first year of the COVID-19 pandemic if convalescent plasma had been used more broadly, particularly in outpatients at high risk for severe disease and in hospitalized patients during their first few days of admission.

4 Oct 2024

Study highlights benefits and risks of doxy-PEP for STI prevention

Taking a dose of the oral antibiotic doxycycline after a high-risk sexual encounter has dramatically reduced the incidence of sexually transmitted infections (STIs) in places where the strategy is being tried.

4 Oct 2024

International experts to gather for ALS symposium in Chicago

The 2024 Les Turner Symposium on ALS will be held on Monday, Nov. 4 in Chicago. Hosted by the Les Turner ALS Foundation and the Les Turner ALS Center at Northwestern Medicine, this event will assemble internationally-renowned ALS researchers, clinicians, advocates, and people living with ALS to discuss the latest research and perspectives on the disease.

3 Oct 2024

Non-invasive imaging technique can accurately detect clear-cell renal cell carcinoma

A new study led by investigators from the UCLA Health Jonsson Comprehensive Cancer Center has demonstrated a new, non-invasive imaging technique can accurately detect clear-cell renal cell carcinoma, the most common form of kidney cancer.

3 Oct 2024

Rice University leads development of innovative bioelectronic implant for obesity and diabetes

Rice University is part of a multiuniversity research team that has secured an award of up to $34.9 million from the Advanced Research Projects Agency for Health (ARPA-H) to accelerate the development of a bioelectronic implant designed to improve adherence for obesity and type 2 diabetes (T2D) treatment while reducing development and manufacturing costs.

3 Oct 2024

Low-dose lithium fails in long COVID trial, but higher doses show potential

A small University at Buffalo clinical trial has found that at low doses, lithium aspartate is ineffective in treating the fatigue and brain fog that is often a persistent feature of long COVID; however, a supplemental dose-finding study found some evidence that higher doses may be effective.

3 Oct 2024

Enhancing the adoption of pragmatic clinical trial results in healthcare systems

A new thought piece led by the Harvard Pilgrim Health Care Institute with collaborators from Duke University and Kaiser Permanente Washington Health Research Institute highlights the challenges facing healthcare researchers and decision makers in the quest to improve population health in a constantly evolving healthcare landscape.

3 Oct 2024

Bioelectronic 'living pharmacy' implant could transform diabetes and obesity care

A Carnegie Mellon University-led team of researchers has secured an award of up to $34.9 million from the Advanced Research Projects Agency for Health (ARPA-H).

3 Oct 2024

Implantable device revolutionizes thyroid management

A Carnegie Mellon University-led team has secured an award of up to $42 million from the Advanced Research Projects Agency for Health (ARPA-H) to accelerate the development of implantable, cell-based bioelectronic devices that deliver patient-specific therapy and monitor disease status, for conditions like hypo- and hyperthyroidism, in real time.

3 Oct 2024

SWOG S1011 trial questions the benefits of extended lymphadenectomy in bladder cancer

The SWOG S1011 randomized phase 3 trial found no significant improvement in disease-free or overall survival but a higher rate of grade 3-4 adverse events and an increased risk of death in the 90 days after surgery.

3 Oct 2024

Mediterranean diet significantly lowers heart failure risk, especially in women

Increased adherence to the Mediterranean diet significantly lowers the risk of heart failure, especially in women, according to a recent European meta-analysis. The diet's anti-inflammatory and antioxidant properties are key to its protective effects.

3 Oct 2024

New treatment proposed for brain metastases resistant to immunotherapy

Researchers at the Spanish National Cancer Research Centre (CNIO) propose a new treatment for brain metastases that respond poorly, or not at all, to immunotherapy, and provide a biomarker to predict in which cases it should be used.

2 Oct 2024

Dronabinol shows promise in reducing agitation in Alzheimer's patients

In a study led by the Johns Hopkins University School of Medicine and Tufts University School of Medicine, researchers show that a pill form of the drug dronabinol, an FDA-approved synthetic version of marijuana's main ingredient, THC, reduces agitation in patients with Alzheimer's by an average of 30%.

2 Oct 2024

Postmenopausal hormone therapy use declines amidst risk-benefit concerns

A study reveals a sharp decline in menopausal hormone therapy use among U.S. women, highlighting disparities across racial and ethnic groups over two decades.

2 Oct 2024

Atherosclerosis progression associated with increased risk of death in asymptomatic individuals

The progression of atherosclerosis in people who have no symptoms of it is independently associated with the risk of dying from any cause, according to a new study led by researchers from Mount Sinai Fuster Heart Hospital, published September 30 in the Journal of the American College of Cardiology.

1 Oct 2024

Time-restricted eating could offer health benefits to adults with metabolic syndrome

More than one-third of adults in the United States have metabolic syndrome, a cluster of conditions that significantly raise a person's risk of heart disease, stroke, and type 2 diabetes.

1 Oct 2024

Immune modulation as a new strategy to combat periodontal disease

Targeting the immune system could prevent or treat periodontal disease (PD), a common but serious disease of the gums, according to new research from the University of Pittsburgh.

30 Sep 2024

Clinical Trial News and Research

Collaborative study investigates underlying cause of neuropsychiatric symptoms in Parkinson's disease

New strategy uses bacteriophages to combat drug-resistant infections

Imagery rescripting offers new hope for treating hoarding disorder

Thousands could have been saved during the pandemic with expanded use of convalescent plasma

Study highlights benefits and risks of doxy-PEP for STI prevention

International experts to gather for ALS symposium in Chicago

Non-invasive imaging technique can accurately detect clear-cell renal cell carcinoma

Rice University leads development of innovative bioelectronic implant for obesity and diabetes

Low-dose lithium fails in long COVID trial, but higher doses show potential

Enhancing the adoption of pragmatic clinical trial results in healthcare systems

Bioelectronic 'living pharmacy' implant could transform diabetes and obesity care

Implantable device revolutionizes thyroid management

SWOG S1011 trial questions the benefits of extended lymphadenectomy in bladder cancer

Mediterranean diet significantly lowers heart failure risk, especially in women

New treatment proposed for brain metastases resistant to immunotherapy

Dronabinol shows promise in reducing agitation in Alzheimer's patients

Postmenopausal hormone therapy use declines amidst risk-benefit concerns

Atherosclerosis progression associated with increased risk of death in asymptomatic individuals

Time-restricted eating could offer health benefits to adults with metabolic syndrome

Immune modulation as a new strategy to combat periodontal disease

Event guide: 15th World Clinical Biomarkers & CDx Europe eBook

Latest eBooks

New horizons in drug discovery: High-throughput & target-to-therapy advances

A practical guide to lipid nanoparticle formulation and resizing

Editorial Focus eBook - Spatial and single-cell omics (1st edition)

Industry Focus eBook - Analytical Chemistry (3rd edition)

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology