Neurons News and Research

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Study detects biomarker changes nearly 30 years before symptom onset of Alzheimer’s disease

A new paper has shown how Alzheimer’s disease pathology comes into being over a period of almost three decades.

10 Aug 2023

"Visual-movement" neurons in the brain help individuals to stay focused on rewarding tasks

Trying to finish your homework while the big game is on TV? "Visual-movement" neurons in the front of your brain can help you stay focused, according to a new study from neuroscientists in the Perelman School of Medicine at the University of Pennsylvania.

9 Aug 2023

GABA transfer between skin cells promotes melanoma initiation

The transfer of a neurotransmitter from one type of skin cell to another (melanocytes to keratinocytes) altered electrical activity and promoted melanoma initiation in preclinical models, according to results published in Cancer Discovery, a journal of the American Association for Cancer Research.

9 Aug 2023

New mechanism discovered for coordinating organ development

Researchers at the Instituto Gulbenkian de Ciência (IGC, Oeiras) and Max Planck Institute of Cell Biology and Genetics (MPI-CBG, Dresden) identified a new mechanism that exposes some of the multitasking abilities embryos need to build a functional retina, the sensory part of the central nervous system responsible for vision.

9 Aug 2023

Mass spectrometry-based secretome approach reveals key players in astroglial barrier function

In neuroinflammation, immune cells such as leukocytes cross the blood-brain barrier. One key to this is the gelatinases matrix metalloproteinase (MMP)-2 and -9. Until now, the substrates of these enzymes involved in the process were unknown.

9 Aug 2023

Are mushrooms an effective early dietary intervention for Alzheimer’s Disease?

In a study published in the journal Foods, researchers reviewed available literature on the potential anti-Alzheimer's disease properties of mushrooms.

9 Aug 2023

Psychedelic drugs cause synchronized brain waves in rats, study finds

Researchers at Lund University have developed a technique for simultaneously measuring electrical signals from 128 areas of the brain in awake rats.

8 Aug 2023

Self-organization of neurons explained using a mathematical theory

An international collaboration between researchers at the RIKEN Center for Brain Science (CBS) in Japan, the University of Tokyo, and University College London has demonstrated that self-organization of neurons as they "learn" follows a mathematical theory called the free energy principle.

8 Aug 2023

Novel tool could help neuroscientists crack the secrets of spinal cord

The spinal cord is harder to access and study than even the brain. The challenges posed by its mobility and anatomical structure have made understanding exactly how it functions difficult.

7 Aug 2023

New antibody shows promise in reversing carfentanil overdoses

An antibody in single-chain fragment variable (scFv) format that binds to the powerful opioid carfentanil was shown to reverse signs of carfentanil overdose in preclinical tests conducted by scientists at Scripps Research.

7 Aug 2023

How does the circulating proteome influence brain health?

Researchers investigate the association between the circulating proteome and brain health.

7 Aug 2023

Childhood abuse can induce stress that changes neural networks and functions during growth

Childhood neglect and/or abuse can induce extreme stress that significantly changes neural networks and functions during growth. This can lead to mental illnesses, including depression and schizophrenia, but the exact mechanism and means to control it were yet to be discovered.

4 Aug 2023

Study reveals mechanism through which insulin-like growth factors facilitate brain plasticity

Research from the Max Planck Florida Institute for Neuroscience has identified a mechanism through which insulin-like growth factors facilitate brain plasticity.

3 Aug 2023

GABA-modulating treatments could help tackle cognitive, affective symptoms associated with depression

Depression is a complex condition correlated with multiple differences in brain function and mechanisms. A new paper spanning known data about the neurotransmitter GABA and its principal receptors showcases evidence of the receptors' importance in depression and potential as therapeutic targets.

3 Aug 2023

Dopamine neurons may play a bigger role in motor control than previously thought

Dopamine: It's not just for rewards anymore. In a new Northwestern University-led study, researchers identified and recorded from three genetic subtypes of dopamine neurons in the midbrain region of a mouse model.

3 Aug 2023

Research sheds light on the causes of endometriosis-related pelvic pain

Pelvic pain in women with endometriosis is attributed to neuroinflammation. Researchers investigated biochemical mediators of endometriosis-associated pelvic pain to provide a foundation to identify new drugs to improve symptoms and quality of life.

3 Aug 2023

Unlocking the potential of Reg3γ: new insights into its metabolic functions and therapeutic prospects

Researchers evaluated the physiological roles of an antimicrobial peptide.

3 Aug 2023

Study finds α5 integrin as a potential therapeutic target in amyotrophic lateral sclerosis

Researchers examined the therapeutic effects of targeting integrins for treating Amyotrophic lateral sclerosis (ALS).

3 Aug 2023

Cerebellum plays a key role in generalized convulsive seizures, study finds

Recurrent seizures are debilitating and can sometimes, be fatal. The onset and presentation of seizures vary significantly among epilepsy patients. Of more than 25 categories of seizure presentations within epilepsy, those with motor convulsions are perhaps the most disruptive and generally most feared among patients and caregivers.

2 Aug 2023

New drug shows promise for treating chronic neuropathic pain

A non-opioid designer molecule for treating chronic neuropathic pain by calming hyperactive pain-sensing neurons in the peripheral nervous system has had promising results in a preclinical study conducted by researchers at Weill Cornell Medicine and the Burke Neurological Institute.

2 Aug 2023

Neurons News and Research

Study detects biomarker changes nearly 30 years before symptom onset of Alzheimer’s disease

"Visual-movement" neurons in the brain help individuals to stay focused on rewarding tasks

GABA transfer between skin cells promotes melanoma initiation

New mechanism discovered for coordinating organ development

Mass spectrometry-based secretome approach reveals key players in astroglial barrier function

Are mushrooms an effective early dietary intervention for Alzheimer’s Disease?

Psychedelic drugs cause synchronized brain waves in rats, study finds

Self-organization of neurons explained using a mathematical theory

Novel tool could help neuroscientists crack the secrets of spinal cord

New antibody shows promise in reversing carfentanil overdoses

How does the circulating proteome influence brain health?

Childhood abuse can induce stress that changes neural networks and functions during growth

Study reveals mechanism through which insulin-like growth factors facilitate brain plasticity

GABA-modulating treatments could help tackle cognitive, affective symptoms associated with depression

Dopamine neurons may play a bigger role in motor control than previously thought

Research sheds light on the causes of endometriosis-related pelvic pain

Unlocking the potential of Reg3γ: new insights into its metabolic functions and therapeutic prospects

Study finds α5 integrin as a potential therapeutic target in amyotrophic lateral sclerosis

Cerebellum plays a key role in generalized convulsive seizures, study finds

New drug shows promise for treating chronic neuropathic pain

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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