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Scientists create new tool to precisely control 3D architecture of linkages in drugs

When it comes to certain molecules, shape makes all the difference. The shape of limonene, for instance, a compound produced by citrus fruits, determines whether it tastes like orange juice or turpentine.

7 Aug 2018

Study: Potential new class of drugs may lower heart disease risk by targeting gut microbes

Cleveland Clinic researchers have designed a potential new class of drugs that may reduce cardiovascular risk by targeting a specific microbial pathway in the gut.

7 Aug 2018

Researchers identify role of infection-fighting cells in inflamed and damaged tissue

Hookworms infect nearly 430 million people in the world, mostly in countries where sanitation is poor, and people often walk barefoot.

7 Aug 2018

Offspring fed with low-protein diet during pregnancy more likely to develop prostate cancer

The offspring of females fed a low-protein diet during pregnancy and lactation are significantly more likely to develop prostate cancer as they age.

7 Aug 2018

Researchers develop drug-delivery system that allows rapid response to heart attacks

Researchers from North Carolina State University and the University of North Carolina at Chapel Hill have developed a drug-delivery system that allows rapid response to heart attacks without surgical intervention.

7 Aug 2018

Blood-based test accurately identifies lung cancer patients who could benefit from immunotherapies

Researchers at UC Davis, Genentech and Foundation Medicine are the first to show that a blood-based test to assess tumor mutational burden accurately identifies non-small cell lung cancer (NSCLC) patients who could benefit from immunotherapies called checkpoint inhibitors.

7 Aug 2018

Study could lead to new diagnostic blood test for Kawasaki disease

For the first time, researchers at University of California San Diego School of Medicine and Imperial College London, with international collaborators, have determined that Kawasaki Disease (KD) can be accurately diagnosed on the basis of the pattern of host gene expression in whole blood. The finding could lead to a diagnostic blood test to distinguish KD from other infectious and inflammatory conditions.

6 Aug 2018

Unique experimental vaccine against Zika virus proves powerful in mice

A uniquely designed experimental vaccine against Zika virus has proven powerful in mice, new research has found.

6 Aug 2018

Study improves understanding of preeclampsia heart damage in pregnancy

Johns Hopkins researchers say a heart imaging study of scores of pregnant women with the most severe and dangerous form of a blood pressure disorder has added to evidence that the condition - known as preeclampsia - mainly damages the heart's ability to relax between contractions, making the organ overworked and poor at pumping blood.

6 Aug 2018

Researchers identify new regulator in breast cancer cells

Triple-negative breast cancer is a particularly aggressive form of breast cancer. Here, important receptors are missing, which often serve as targets for treatments.

6 Aug 2018

Researchers report new way to map the inner workings of a living cell

Imaging tools like X-rays and MRI have revolutionized medicine by giving doctors a close up view of the brain and other vital organs in living, breathing people. Now, Columbia University researchers report a new way to zoom in at the tiniest scales to track changes within individual cells.

6 Aug 2018

New high-sensitivity blood test quickly rules out heart attack in emergency room patients

A new test to assess a whether or not someone is having a heart attack upon arriving in the emergency room was safe and effective, ruling out heart attack in emergency room patients faster than a conventional method, according to new research in the American Heart Association's journal Circulation.

6 Aug 2018

Research uncovers new approach for expanding stem cells from umbilical cord blood

Researchers from the Stowers Institute for Medical Research and collaborators have identified a way to expand blood-forming, adult stem cells from human umbilical cord blood.

3 Aug 2018

Cocaine relapse is reduced in preclinical model with BDNF administration

Cocaine relapse was significantly reduced in a preclinical model when brain-derived neurotropic factor was applied to the nucleus accumbens deep in the brain immediately before cocaine-seeking behavior, report investigators at the Medical University of South Carolina in an article published online in June 2018 by Addiction Biology.

3 Aug 2018

Consuming crickets can help support growth of beneficial gut bacteria, clinical trial shows

Valerie Stull was 12 when she ate her first insect. "I was on a trip with my parents in Central America and we were served fried ants," she says. "I remember being so grossed out initially, but when I put the ant in my mouth, I was really surprised because it tasted like food -- and it was good!"

3 Aug 2018

Protein C News and Research

Scientists create new tool to precisely control 3D architecture of linkages in drugs

Study: Potential new class of drugs may lower heart disease risk by targeting gut microbes

Researchers identify role of infection-fighting cells in inflamed and damaged tissue

Offspring fed with low-protein diet during pregnancy more likely to develop prostate cancer

Researchers develop drug-delivery system that allows rapid response to heart attacks

Blood-based test accurately identifies lung cancer patients who could benefit from immunotherapies

Study could lead to new diagnostic blood test for Kawasaki disease

Unique experimental vaccine against Zika virus proves powerful in mice

Study improves understanding of preeclampsia heart damage in pregnancy

Researchers identify new regulator in breast cancer cells

Researchers report new way to map the inner workings of a living cell

New high-sensitivity blood test quickly rules out heart attack in emergency room patients

Research uncovers new approach for expanding stem cells from umbilical cord blood

Cocaine relapse is reduced in preclinical model with BDNF administration

Consuming crickets can help support growth of beneficial gut bacteria, clinical trial shows

Researchers shed new light on how bacteria sense nutrients in their environment

Discovery of new epithelial lung cell type may affect cystic fibrosis therapy

Monash researchers identify new mechanism used by Henipaviruses in infection

Alcohol increases mortality in young mice infected with tuberculosis-causing bacterium

Study sheds new light on link between calorie-burning fat and muscle function

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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