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Scientists use new drug discovery system to target Huntington’s Disease

Scientists have used a new drug discovery system to specifically target phosphatases in Huntington's, which were previously thought to be undruggable.

27 Jul 2018

Scientists use new drug discovery system to target Huntington’s Disease

Scientists have used a new drug discovery system to specifically target phosphatases in Huntington's, which were previously thought to be undruggable.

27 Jul 2018

Newer version of ALS drug may effectively treat inherited form of the disease

NIH-funded researchers delayed signs of amyotrophic lateral sclerosis in rodents by injecting them with a second-generation drug designed to silence the gene, superoxide dismutase 1.

27 Jul 2018

Researchers identify genes linked to childhood nephrotic syndrome

Childhood nephrotic syndrome is the most frequently occurring chronic kidney disease among children. A Japanese research team has identified a group of genes that are strongly related to the development of childhood nephrotic syndrome.

27 Jul 2018

Researchers discover new protein that controls level of inflammation-inducing molecule

One of the major therapeutic targets for inflammatory diseases is the inflammation-inducing molecule TNF. However, excess levels of TNF cause side effects and can lead to diseases.

27 Jul 2018

Answer to decades-old mystery may allow some children to avoid bone marrow transplantation

Researchers have helped solve a decades-old mystery about which mutations are responsible for an inherited bone marrow disorder.

27 Jul 2018

New drug discovery system allows scientists to target ‘undruggable’ enzymes

A new drug discovery system allows scientists to specifically target members of an important family of enzymes, called phosphatases, which were previously considered mostly "undruggable".

27 Jul 2018

Scientists take important step to understand mechanisms that cause Huntington's disease

The neuroscientist Dr David Vilchez and his team at CECAD, the University of Cologne's Cluster of Excellence for Aging Research, have made an important step towards understanding the mechanisms that cause the neurodegenerative disorder Huntington's disease.

27 Jul 2018

Discovery of two molecules could pave way for new drugs to treat traumatic brain injury

After 10 years of research, a Rutgers-led team of scientists has identified two molecules that protect nerve cells after a traumatic brain injury and could lead to new drug treatments.

27 Jul 2018

Mutations of IRF2BPL gene associated with previously undiagnosed neurological disorder

An international team of scientists, including researchers from Baylor College of Medicine, has discovered mutations of gene IRF2BPL that are associated with a previously undiagnosed neurological disorder in seven unrelated individuals.

27 Jul 2018

Duke engineers develop new technique to manipulate, split and mix droplets of biological fluids

Engineers at Duke University have developed a way to manipulate, split and mix droplets of biological fluids by having them surf on acoustic waves in oil.

26 Jul 2018

Research findings may offer new path to treat or prevent neurodegenerative diseases

Aging vessels connecting the brain and the immune system play critical roles in both Alzheimer's disease and the decline in cognitive ability that comes with time, new research reveals.

26 Jul 2018

New drug offers hope to prevent attacks of hereditary angioedema

Hereditary angioedema is a chronic disorder that can sometimes be life-threatening. Now, a new drug therapy has been successfully tested in an international study headed by the University Hospital Frankfurt.

26 Jul 2018

New mouse model shows great promise for Rett syndrome research

In an article released today from Jeannie T. Lee, MD PhD of Massachusetts General Hospital, there is hope on the horizon for future research specific to Rett syndrome, a rare childhood neurodevelopmental disorder.

26 Jul 2018

Study supports clinical role of biomarker test to rule out the need for CT scan in TBI patients

Banyan Biomarkers, Inc., a pioneer in developing biomarkers for traumatic brain injury (TBI), today announced the publication of the results for the ALERT-TBI study, an international, multicenter clinical trial utilizing the Banyan Brain Trauma Indicator.

26 Jul 2018

Researchers design and create new molecule that can kill malarial parasites

A research team from The Australian National University and The University of Queensland has designed and made a molecule derived from a human protein that kills the parasite which causes malaria.

26 Jul 2018

How soon is soon enough to learn you have Alzheimer’s?

Jose Belardo of Lansing, Kan., spent most of his career in the U.S. Public Health Service. He worked on the front lines of disasters in such places as Haiti, Colombia, Nicaragua and the Dominican Republic. At home with his three kids and wife, Elaine, he’d always been unfailingly reliable, so when he forgot their wedding anniversary two years in a row, they both started to worry.

26 Jul 2018

New blood test helps patients with traumatic head injury to avoid costly CT scan

Research conducted at the Wayne State University School of Medicine has helped confirm the effectiveness of a blood biomarker that can indicate if patients with a head injury can avoid a costly CT scan because the blood test results indicate no traumatic brain injury

26 Jul 2018

Newly identified target may lead to discovery of treatments for chronic inflammatory diseases

Inflammation is part of the body's natural healing process. But when it becomes chronic, inflammation can lead to cancer, Alzheimer's disease and other conditions.

26 Jul 2018

Scientists uncover new strategy to kill tumors without harming healthy cells

Scientists at Scripps Research have uncovered a new strategy to kill tumors, including some triple-negative breast cancers, without harming healthy cells, a discovery that could lead to more ways to treat tumors while reducing side effects.

26 Jul 2018

Protein C News and Research

Scientists use new drug discovery system to target Huntington’s Disease

Scientists use new drug discovery system to target Huntington’s Disease

Newer version of ALS drug may effectively treat inherited form of the disease

Researchers identify genes linked to childhood nephrotic syndrome

Researchers discover new protein that controls level of inflammation-inducing molecule

Answer to decades-old mystery may allow some children to avoid bone marrow transplantation

New drug discovery system allows scientists to target ‘undruggable’ enzymes

Scientists take important step to understand mechanisms that cause Huntington's disease

Discovery of two molecules could pave way for new drugs to treat traumatic brain injury

Mutations of IRF2BPL gene associated with previously undiagnosed neurological disorder

Duke engineers develop new technique to manipulate, split and mix droplets of biological fluids

Research findings may offer new path to treat or prevent neurodegenerative diseases

New drug offers hope to prevent attacks of hereditary angioedema

New mouse model shows great promise for Rett syndrome research

Study supports clinical role of biomarker test to rule out the need for CT scan in TBI patients

Researchers design and create new molecule that can kill malarial parasites

How soon is soon enough to learn you have Alzheimer’s?

New blood test helps patients with traumatic head injury to avoid costly CT scan

Newly identified target may lead to discovery of treatments for chronic inflammatory diseases

Scientists uncover new strategy to kill tumors without harming healthy cells

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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