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Glenmark announces discovery and initiation of IND enabling studies of innovative bispecific antibody

Glenmark Pharmaceuticals S.A. (GPSA), a wholly owned subsidiary of Glenmark Pharmaceuticals Limited India (GPL), announces the discovery and initiation of IND enabling studies of a novel clinical development candidate, GBR 1302, a HER2xCD3 bispecific antibody.

20 Aug 2014

Houston Methodist researchers receive $1.6M from NIH to study pathological antibodies

Transplant immunologists at the Houston Methodist Research Institute will receive about $1.6 million over four years from the National Institute of Allergy and Infectious Diseases to study pathological antibodies produced from activated memory B cells during the chronic rejection of organ transplants.

20 Aug 2014

Death rate increases with hospitals shift from inpatient procedures to outpatient for urological surgeries

As hospitals have shifted an array of common urological surgeries from inpatient procedures to outpatient, potentially preventable deaths have increased following complications.

20 Aug 2014

Studies support clinical use of antidepressants for treatment of postoperative pain

Antidepressants are known to provide effective pain relief for various chronic pain conditions; however, the jury is still out on their use in treating the millions of patients who suffer from acute or chronic pain following surgery.

20 Aug 2014

Study suggests mental illness doesn't preclude enjoying life

Schizophrenia is among the most severe forms of mental illness, yet some people with the disease are as happy as those in good physical and mental health according to a study led by researchers at the University of California, San Diego School of Medicine.

19 Aug 2014

Mount Sinai researchers receive federal funding to treat HCV in primary care settings

With the number of people with chronic hepatitis C reaching record levels in New York City and the recent availability of more effective treatments, researchers from the Icahn School of Medicine at Mount Sinai recently announced the receipt of $1.9 million in federal funding to increase its capacity to treat HCV in primary care settings.

19 Aug 2014

Consumer groups: Chronically ill still face insurer discrimination

Patient advocacy groups are complaining to federal officials that some insurers' policies, such as the high prices charged for certain drugs, "are highly discriminatory against people with chronic health conditions."

19 Aug 2014

Medicare to begin paying physicians to coordinate care for patients with chronic illnesses

In a policy change, the Obama administration is planning to pay doctors to coordinate the care of Medicare beneficiaries, amid growing evidence that patients with chronic illnesses suffer from disjointed, fragmented care.

19 Aug 2014

Doctors test device designed to 'turn off' cluster headaches

For those suffering excruciating pain from cluster headaches, relief may soon be available from an investigational device being studied in a national multicenter clinical trial. Recently, doctors at The Ohio State University Wexner Medical Center performed the first surgery in the United States to insert a neurostimulator to provide relief from cluster headaches, which are more painful than migraines.

19 Aug 2014

Amgen’s AMG 416 Phase 3 placebo-controlled study meets primary and secondary endpoints

Amgen (NASDAQ: AMGN) today announced that a second placebo-controlled Phase 3 study evaluating AMG 416 for the treatment of secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease (CKD), receiving hemodialysis, met its primary and all secondary endpoints.

19 Aug 2014

Innate lymphoid cells induce specific T and B cell responses during inflammation

In case of an inflammation the body releases substances that increase the immune defense. During chronic inflammation, this immune response gets out of control and can induce organ damage.

19 Aug 2014

Decision Resources expands disease-level coverage of Treatment Algorithms Insight Series

Decision Resources has expanded its disease-level coverage of the Treatment Algorithms Insight Series, which examines U.S. physicians' prescribing behavior, to provide a quantitative analysis of an agent's penetration into each line of therapy.

19 Aug 2014

Physical activity fails to show link with chronic musculoskeletal pain

Neither little nor excessive physical activity contributes to chronic musculoskeletal pain in people who are middle-aged or older, Japanese study findings suggest.

18 Aug 2014

Chronic musculoskeletal pain influenced by genetics

Children of parents with chronic musculoskeletal pain are at increased risk of also suffering from such pain as adults, a large family-linkage study shows.

18 Aug 2014

Meta-analysis shows blood pressure variability and mortality link

A systematic review and meta-analysis of studies investigating the link between visit-to-visit variability of blood pressure and cardiovascular disease or all-cause mortality has revealed a modest, but significant, association.

18 Aug 2014

First Edition: August 18, 2014

Today's headlines stories about the pervasive nature of Medicare fraud and the difficulties involved in fighting it.

18 Aug 2014

ITS develops new T cell vaccine to protect humans from seasonal and pandemic influenza A

Immune Targeting Systems, specializing in the development of novel T cell immune therapies, has been developing an exciting new T cell vaccine (FlunisynTM) designed to protect humans from all strains of seasonal and pandemic influenza A.

18 Aug 2014

Women seek hormonal treatments for menopausal symptoms from anti-aging clinicians

Feeling that conventional doctors did not take their suffering seriously, women instead sought out hormonal treatments for menopausal symptoms from anti-aging clinicians, according to a Case Western Reserve University study that investigated the appeal of anti-aging medicine.

18 Aug 2014

Study reports rising prevalence of chronic opioid use by SSDI recipients

More than 40 percent of Social Security Disability Insurance recipients take opioid pain relievers, while the prevalence of chronic opioid use is over 20 percent and rising, reports a study in the September issue of Medical Care.

16 Aug 2014

Study finds link between common respiratory diseases and increased risk of lung cancer

Links between a number of common respiratory diseases and an increased risk of developing lung cancer have been found in a large pooled analysis of seven studies involving more than 25,000 individuals.

16 Aug 2014

Chronic News and Research

Glenmark announces discovery and initiation of IND enabling studies of innovative bispecific antibody

Houston Methodist researchers receive $1.6M from NIH to study pathological antibodies

Death rate increases with hospitals shift from inpatient procedures to outpatient for urological surgeries

Studies support clinical use of antidepressants for treatment of postoperative pain

Study suggests mental illness doesn't preclude enjoying life

Mount Sinai researchers receive federal funding to treat HCV in primary care settings

Consumer groups: Chronically ill still face insurer discrimination

Medicare to begin paying physicians to coordinate care for patients with chronic illnesses

Doctors test device designed to 'turn off' cluster headaches

Amgen’s AMG 416 Phase 3 placebo-controlled study meets primary and secondary endpoints

Innate lymphoid cells induce specific T and B cell responses during inflammation

Decision Resources expands disease-level coverage of Treatment Algorithms Insight Series

Physical activity fails to show link with chronic musculoskeletal pain

Chronic musculoskeletal pain influenced by genetics

Meta-analysis shows blood pressure variability and mortality link

First Edition: August 18, 2014

ITS develops new T cell vaccine to protect humans from seasonal and pandemic influenza A

Women seek hormonal treatments for menopausal symptoms from anti-aging clinicians

Study reports rising prevalence of chronic opioid use by SSDI recipients

Study finds link between common respiratory diseases and increased risk of lung cancer

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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