Protein C News and Research

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'Hijacked' cell response to stress reveals potential therapeutic targets for leukemia

A signaling pathway that helps promote normal cell growth worsens a form of leukemia by taking control of another pathway better known for protecting cells from biological stress, a new study shows.

24 Jul 2018

Researchers explore why heart failure and kidney disease correlate

People with chronic kidney disease are at unusually high risk of also developing cardiovascular disease; in fact, a patient with non-dialysis kidney disease is more likely to die of heart failure than to develop end-stage kidney failure.

24 Jul 2018

New study provides important clues to developing more effective Ebola vaccines

Scientists conducting the first comprehensive study of key immune system cells - collected from West African Ebola survivors that kill Ebola infected cells have made a surprising discovery that provides important clues to developing effective vaccines against the infection.

24 Jul 2018

Scientists find abnormal gene copying in fruit fly models of tauopathies

It sounds like science fiction: Nefarious genes clone themselves and settle their rogue copies in distant outposts of the galaxy (namely, our DNA), causing disease.

24 Jul 2018

Research shows how experience alters the basics of memory formation

We know instinctively that our experiences shape the way we learn. If we are highly familiar with a particular task, like cooking for example, learning a new recipe is much easier than it was when we were a novice.

24 Jul 2018

Simple saliva test could lead to better prediction and prevention of diabetes

Diabetes assessment currently relies on measurement of blood sugar levels -- but a simple saliva sample could replace this, says new research.

23 Jul 2018

Study finds new enzyme that lays foundations for allergic immune response

While in search of the causes of allergies and asthma, a chance discovery has yielded new clues: researchers led by Dr Marcus Peters have ascertained that the enzyme guanylate cyclase in cells lays the foundations for the type of immune response.

23 Jul 2018

Experts make breakthrough in the fight against Type 2 diabetes

Experts from the University of Stirling have made a breakthrough in understanding how people respond to lifestyle treatment for preventing Type 2 diabetes.

23 Jul 2018

Discovery about how malaria moves could lead to new therapies

Researchers have made an important discovery about how Plasmodium falciparum (the parasite that causes malaria) is able to evade capture by the immune system.

23 Jul 2018

MOF vaccines could increase access to immunization and reduce the risk of global pandemics

Vaccinations are the safest way to protect against disease. However, many vaccines become ineffective when exposed to room temperature or heat.

23 Jul 2018

Researchers present evidence of phage cooperation when attacking CRISPR-containing bacteria

CRISPR, or clustered regularly interspaced short palindromic repeats, are an essential part of bacterial immunity designed to defend against foreign DNA. In bacteria, CRISPR acts just like it does in human cells as a pair of scissors, in their case with the goal of cutting strands of infecting DNA.

20 Jul 2018

Scientists find reason why malarial parasites are faster than immune cells

Elementary cytoskeleton protein is different in parasites and represents a starting point for a possible new therapy against malaria infections.

20 Jul 2018

Whole-brain LIPUS therapy improves cognitive dysfunction in mice simulating dementia, Alzheimer's

Ultrasound waves applied to the whole brain improve cognitive dysfunction in mice with conditions simulating vascular dementia and Alzheimer's disease.

20 Jul 2018

Dr Maddy Parsons receives Royal Microscopical Society Life Science Medal

Dr Maddy Parsons, a Group Leader in the Randall Division of Cell & Molecular Biophysics, has been awarded the Royal Microscopical Society Life Science Medal for her outstanding scientific contribution to applying microscopy in the field of cell biology.

20 Jul 2018

Researchers design proteins that can self-assemble into complex structures

A collaborative research team based in Japan has designed new proteins that can self-assemble into the complex structures underlying biological organisms, laying the groundwork for leading-edge applications in biotechnology.

20 Jul 2018

Genetic sequencing reveals new clues to aggressiveness of prostate cancer

Using genetic sequencing, scientists have revealed the complete DNA makeup of more than 100 aggressive prostate tumors, pinpointing important genetic errors these deadly tumors have in common.

20 Jul 2018

Novel tool predicts genes that cause disease due to production of truncated proteins

Predicting genes that can cause disease due to the production of truncated or altered proteins that take on a new or different function, rather than those that lose their function, is now possible thanks to an international team of researchers, including researchers from Baylor College of Medicine, that has developed a new analytical tool to effectively and efficiently predict such candidate genes.

20 Jul 2018

Researchers identify enzyme as potential new drug target for blood disorders

Medical researchers have identified a key signaling protein that regulates hemoglobin production in red blood cells, offering a possible target for a future innovative drug to treat sickle cell disease.

20 Jul 2018

Top AI companies join hands to discover novel drugs for DMD

Insilico Medicine a leader in artificial intelligence for drug discovery, biomarker development and aging research, announced a research collaboration agreement with A2A Pharmaceuticals, Inc. A2A is a biotechnology company headquartered in New York and focused on development of novel drugs for unmet needs in oncology, drug resistant bacterial infections, and other life threatening diseases.

20 Jul 2018