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ZHX2 protein could offer a new treatment strategy for kidney cancer

University of North Carolina Lineberger Comprehensive Cancer Center scientists have uncovered a potential therapeutic target for kidney cancers that have a common genetic change.

20 Jul 2018

New discovery could save millions of lives from fatal fungal infections

Life-threatening fungal infections affect more than two million people worldwide. Effective antifungal medications are very limited.

20 Jul 2018

Scientists demonstrate a new regulation mechanism for skeletal muscles

An international team of scientists from the University of Florence, Italy and the Randall Division in collaboration with the ESRF, the European Synchrotron, Grenoble, France, demonstrated a new regulation mechanism for skeletal muscle.

20 Jul 2018

Gestational diabetes may increase offspring's heart disease risk

Gestational diabetes may increase the risk of blood vessel dysfunction and heart disease in offspring by altering a smooth muscle protein responsible for blood vessel network formation.

19 Jul 2018

Scientists discover protein regulator of myelin production

Scientists have made an important discovery about the role of a protein called PRMT5 in the production of myelin.

19 Jul 2018

Biophysicists use infrared sensor as new method for drug discovery

Using an infrared sensor, biophysicists at Ruhr-Universität Bochum have succeeded in analyzing quickly and easily which active agents affect the structure of proteins and how long that effect lasts.

19 Jul 2018

Study uncovers new protein complex that shields broken DNA ends

Scientists have made a major discovery about how cells repair broken strands of DNA that could have huge implications for the treatment of cancer.

19 Jul 2018

Gene regulator associated with protein pileup in exfoliation glaucoma

In exfoliation glaucoma, a protein dandruff clogs the outflow pathway for the fluid in our eyes.

19 Jul 2018

Understanding triple-negative breast cancer to develop better treatments

Breast cancer affects 1 in 8 women in her lifetime. Among the various types, triple-negative breast cancer is the rarest and most aggressive – affecting about 15 percent of breast cancer patients. It is also the least studied.

19 Jul 2018

Researchers unravel how ALL invades the central nervous system

A deadly feature of acute lymphoblastic leukemia is its invasion of the central nervous system.

19 Jul 2018

Health impact of highly processed summertime staples

With the 4th of July in the rearview mirror and Labor Day coming down the pike, barbecue season is in full swing.

19 Jul 2018

Study identifies RNA molecules that regulate male hormones in prostate cancer

In most cases of prostate cancer, tumor cell growth is stimulated by the action of male hormones, or androgens, such as testosterone and dihydrotestosterone.

19 Jul 2018

Sweetness depends on molecular interactions between specific sugars and water in saliva

A cranberry, honey or a candy bar - which tastes the sweetest? These foods contain sugars that humans can perceive differently.

19 Jul 2018

New proteomics studies help gain more insights into Alzheimer's, cancer and listeriosis

The brains of people with Alzheimer's disease contain many protein aggregates outside of cells, known as plaques. These are mainly made of the peptide amyloid-beta, which is released from the plasma membrane when the protease BACE1 cleaves its membrane-anchored precursor protein.

19 Jul 2018

Researchers gain more insight into how FUS protein causes ALS and FTLD

The mutated and aggregated protein FUS is implicated in two neurodegenerative diseases: amyotrophic lateral sclerosis and frontotemporal lobar degeneration.

19 Jul 2018

Cancer patients receiving anti-PD-1 therapies may experience delayed skin reactions

Cancer patients receiving anti-PD-1 therapies who develop lesions, eczema, psoriasis, or other forms of auto-immune diseases affecting the skin may experience those adverse reactions on a delay – sometimes even after treatment has concluded.

19 Jul 2018

Scientists identify melanoma biomarkers that could help tailor immunotherapy treatments

Scientists at Dana-Farber/Brigham and Women's Cancer Center have identified biomarkers in melanoma that could help tailor immunotherapy treatments to maximize the benefits for patients while reducing the likelihood of severe side effects.

19 Jul 2018

Research uncovers new target for therapeutic intervention in breast cancer

Research led by Suresh Alahari, PhD, Professor of Biochemistry and Molecular Biology at LSU Health New Orleans School of Medicine, has shown for the first time that a tiny piece of RNA deregulates energy metabolism, an emerging hallmark of cancer. The finding identifies a new target for therapeutic intervention in breast cancer.

18 Jul 2018

New strategy may lead to more accurate breast cancer diagnoses

A study in Molecular Oncology indicates that examining the protein and RNA in leftover materials from routine diagnostic tests for breast cancer may lead to more accurate diagnoses.

18 Jul 2018

Heart attack risk continues to increase among pregnant women, study finds

The risk of having a heart attack while pregnant, giving birth, or during the two months after delivery, continues to increase for American women, a new study finds.

18 Jul 2018