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Unexpected behavior observed during interactions between immune cells and dying cells

Over the years, cell biology has built a detailed picture of how cells compartmentalize their internal functions. Central to this organization is the nucleus, which houses the genetic material and is separated from the cytoplasm by a robust nuclear envelope.

25 Feb 2026

Breakthrough gene therapy for sickle cell disease remains out of reach in Africa

As Uganda rolls out mandatory nationwide screening of newborns for sickle cell disease this month, a gene therapy celebrated in the United States and Europe remains financially out of reach for most patients in Africa.

25 Feb 2026

Simple blood test measuring piRNAs may help better understand health and aging

Research in Aging Cell indicates that blood levels of particular small non-coding RNAs, which regulate gene expression, may influence how long a person lives.

25 Feb 2026

Small RNA molecules can accurately predict survival in older adults

As people age, it becomes harder to know who is on track for healthy years ahead and who may be at higher risk for serious decline.

25 Feb 2026

Element Biosciences introduces VITARI™, redefining what high-throughput sequencing makes possible

Element Biosciences Inc. today announced VITARI, the first ever high-throughput benchtop sequencing system capable of delivering a high-quality whole genome at $100.

25 Feb 2026

New Pico C technology maps genome structure before activation

For decades, scientists viewed the genome of a newly fertilised egg as a structural 'blank slate' – a disordered tangle of DNA waiting for the embryo to 'wake up' and start reading its own genetic instructions.

24 Feb 2026

Study identifies mitochondrial circular RNAs in aging and senescence

A new research paper was published in Volume 18 of Aging-US on February 10, 2026, titled "Aging-associated mitochondrial circular RNAs."

24 Feb 2026

Automated platform finds unexpected enhancers for mRNA therapeutics

Integrating AI with advanced robotics to create self-driving labs (SDL) is a promising approach to tackling molecular discovery.

24 Feb 2026

Researchers uncover vulnerabilities in elusive HIV reservoir clones

A new study has overcome a long-standing challenge-how to isolate and study elusive HIV-infected cells called authentic reservoir clones (ARCs) that evade the immune system, making the disease difficult to cure.

24 Feb 2026

Study sheds light on behavior of yeast cells in the gut

A new study sheds light on the behavior of yeast cells in the gut, paving the way for new lines of yeast that more efficiently produce therapeutic drugs tailored to address specific diseases.

24 Feb 2026

Combined GLP-1 and GLP-2 treatment appears safe but does not beat placebo for obesity

In a 12-week randomized phase IIa trial in adults with obesity, the dual GLP-1/GLP-2 receptor agonist dapiglutide was well tolerated but did not achieve statistically significant weight loss compared with placebo at 4 mg or 6 mg doses. Although the higher dose showed modest within-group weight reduction and improved HbA1c, unexpectedly substantial placebo-associated weight loss limited the observed treatment effect.

24 Feb 2026

Viral RNA modifications trigger celiac inflammation

An EHU study indicates that a drug already approved for use in humans could help to reduce the inflammation associated with celiac disease.

24 Feb 2026

ATG14 found to be a critical defender against hepatic injury and fibrosis

Autophagy is indispensable for maintaining hepatocyte integrity, metabolic homeostasis, and survival. While several autophagy-related proteins have been studied in hepatic physiology, the specific role of Autophagy Related 14 (ATG14) in liver health has remained unclear.

24 Feb 2026

Throwing cancer-driving proteins in the cellular trash

When cancer-driving proteins resist various treatments, Northwestern University scientists have uncovered a new solution. Don't fight them - throw them in the cellular trash.

24 Feb 2026

Swiss centenarians show youthful blood protein profiles in aging study

In Switzerland, 0.02% of the population lives beyond the age of 100. Could there be biological characteristics associated with this exceptional longevity? As part of the "SWISS100" study, the first large-scale Swiss research project dedicated to centenarians, a team from the University of Geneva (UNIGE) and the University of Lausanne (UNIL) compared the blood profiles of centenarians with those of octogenarians, and then with those of individuals aged 30 to 60.

24 Feb 2026

Assessing long-term cognitive risks in ependymoma survivors

A study led by St. Jude Children's Research Hospital assessed cognitive and communication abilities in children treated for the brain tumor ependymoma to understand the impact of treatment better. They found that radiation was a significant contributor to hearing loss, a risk directly linked to cognitive health.

23 Feb 2026

Transforming obese fat cells into energy burners

Ordinary fat cells in obese animals can be induced to burn energy stores, generating substantial heat, according to a preclinical study by Weill Cornell Medicine investigators.

23 Feb 2026

Ochsner MD Anderson Cancer Center delivers Louisiana’s first TIL therapy for melanoma

Ochsner MD Anderson Cancer Center at The Gayle and Tom Benson Cancer Center in New Orleans announces a milestone in advanced cancer treatment, as the first institution in Louisiana to provide an adult patient with tumor-infiltrating lymphocytes (TIL) therapy for advanced melanoma.

23 Feb 2026

Unmasking the impact of C. neoformans as a Global Menace

Cryptococcus neoformans is one of four fungi classified as 'critical priority' on the WHO's Fungal Pathogens Priority List, which was published in October 2022 following decades of research and calls for fungal pathogens to be classified alongside their bacterial and viral counterparts.

23 Feb 2026

Osteoporosis drugs show promise against toxic iron accumulation

Researchers at the University of São Paulo (USP) in Brazil have discovered that two osteoporosis drugs (etidronate and tiludronate) may combat diseases caused by iron accumulation in the body.

23 Feb 2026