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Diabetes and elevated levels of cholesterol linked to cognitive decline in Alzheimer's

A history of diabetes and elevated levels of cholesterol, especially LDL cholesterol, are associated with faster cognitive decline in patients with Alzheimer's disease, according to a new study from Columbia University Medical Center researchers.

10 Mar 2009

Advances in stem cell research

Scientists at The University of Texas Health Science Center at Houston are on the forefront of stem cell research, developing novel therapies designed to generate heart cells, repair traumatic lung injuries, grow new bone and stanch the spread of cancer cells.

8 Mar 2009

Molecule tracking reveals mechanism of chromosome separation in dividing cells

University of Washington (UW) researchers are helping to write the operating manual for the nano-scale machine that separates chromosomes before cell division.

8 Mar 2009

Abdominal obesity puts the squeeze on lungs

There's more bad news for people who carry excess weight around their waists: Not only is abdominal obesity associated with diabetes, hypertension, cardiovascular disease and a host of other health problems collectively known as "metabolic syndrome," a new study has found that a high waist circumference is strongly associated with decreased lung function-independent of smoking history, sex, body mass index (BMI) and other complicating factors.

8 Mar 2009

European Commission and US FDA approve intravenous formulation of temozolomide

Schering-Plough Corporation (NYSE:SGP) today announced that the European Commission and the US FDA both approved the intravenous (IV) formulation of temozolomide as an alternative to the already approved oral form of the drug.

5 Mar 2009

Experimental microbicide containing natural compound provides protection in monkeys against simian version of HIV

An experimental microbicide containing a naturally occurring compound provides protection in monkeys against the simian version of HIV by diminishing immune responses to the virus, according to a study published Wednesday in the journal Nature, the Los Angeles Times reports.

5 Mar 2009

Birth control shot causes significant weight gain

Women using depot medroxyprogesterone acetate (DMPA), commonly known as the birth control shot, gained an average of 11 pounds and increased their body fat by 3.4 percent over three years, according to researchers at the University of Texas Medical Branch (UTMB).

4 Mar 2009

Genetic link between cats and humans for retinitis pigmentosa

About one in 3,500 people are affected with retinitis pigmentosa (RP), a disease of the retina's visual cells that eventually leads to blindness.

4 Mar 2009

Being fat increases the risk of primary joint replacement in osteoarthritis

A study published in BioMed Central's open access journal, Arthritis Research & Therapy , found that increased waist circumference and body mass index (BMI) were associated with the risk of both knee and hip joint replacement.

4 Mar 2009

Study offers clues to beating hearing loss

Researchers at the University of Leeds have made a significant step forward in understanding the causes of some forms of deafness.

4 Mar 2009

Opioid antagonists help pain management

Achieving effective, durable, and safe pain relief, especially in patients with chronic and/or severe pain conditions, can be difficult.

3 Mar 2009

Missing link between fructose, insulin resistance found

A new study in mice sheds light on the insulin resistance that can come from diets loaded with high-fructose corn syrup, a sweetener found in most sodas and many other processed foods.

3 Mar 2009

Trial looks at telmisartan in treating non-alcoholic steatohepatitis

Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are well-recognized causes of progressive liver disease leading to cirrhosis and hepatocellular carcinoma.

3 Mar 2009

Certain combined medications after heart attack may increase risk of death

Following an acute coronary syndrome such as a heart attack or unstable angina, patients who receive a medication to reduce the risk of gastrointestinal bleeding that may be associated with the use of the antiplatelet drug clopidogrel and aspirin have an increased risk of subsequent hospitalization for acute coronary syndrome or death, according to a study in the March 4 issue of JAMA, the Journal of the American Medical Association.

3 Mar 2009

Study looks at effect of vitamin B6, folate, and vitamin B12 supplements in coeliac disease

Coeliac disease is a typical example of a malabsorption syndrome conferring increased risk for various deficiency states, including folate and vitamin B12.

3 Mar 2009

Discovery of genetic variation linked to both autism and gastrointestinal dysfunction

A study led by researchers at the University of Southern California (USC) and Vanderbilt University have identified a specific gene variant that links increased genetic risk for autism with gastrointestinal (GI) conditions.

2 Mar 2009

New treatment target for chronic abdominal pain

High levels of a protein linked to the way pain signals are sent to the brain led to a decrease in abdominal pain in a recent study in mice.

2 Mar 2009

Newly discovered protein points to new treatment for serious lung disease

The discovery by Uppsala University researchers of a previously unknown protein in the cells of the lower air ways brings new potential for early diagnosis of a serious lung disease.

2 Mar 2009

Discovery of new potential therapeutic target for Barth Syndrome

Researchers at NYU Langone Medical Center may have discovered a new targeted intervention for Barth Syndrome (BTHS).

2 Mar 2009

Educational materials for new mothers may prevent shaken baby syndrome

Educational materials on how to deal with crying newborns lead to increased knowledge about infant crying and behaviours that are important to preventing shaken baby syndrome, found two new studies being published online March 2 in CMAJ (Canadian Medical Association Journal) and Pediatrics.

2 Mar 2009