Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Scientists discover weakness in common cold virus

Scientists have discovered a weakness on the surface of the viruses that cause a multitude of illnesses.

12 Jun 2019

Boehringer Ingelheim and University of Dundee extend collaboration to develop new cancer medicines

Following the success of their ongoing alliance, Boehringer Ingelheim and the University of Dundee extend their collaboration to develop new medicines that target and destroy key cancer causing proteins.

12 Jun 2019

Biomarker correlates with prostate cancer aggressiveness and predicts metastasis to bone

Mortality due to prostate cancer is usually related to its likelihood to metastasize, especially to bone. Prognostic biomarkers are urgently needed to predict disease aggression so that appropriate treatment can be selected.

12 Jun 2019

Chemists build rich collection of natural product-like macrocycles for drug discovery

Natural products, or their close derivatives, make some of our most potent medicines, among which macrocycles with their large carbon-rich ring systems are one class.

12 Jun 2019

Researchers develop new gene-targeted approach to study chronic wasting disease in mice

Infectious proteins called prions cause a group of related, fatal and incurable neurodegenerative disorders, including bovine spongiform encephalopathy or Mad Cow disease and Creutzfeldt-Jakob disease, both of which affect humans.

12 Jun 2019

New research identifies cellular adaptive mechanisms during hypoxic conditions

Circadian rhythms are 24 hour cycles that are guided by exposure to alternating periods of day and night. These cycles affect biological activities in a variety of living organisms which are attuned to the circadian clock.

12 Jun 2019

Fibrinogen a key player in health and disease, says new study

A new study from the University of Alberta demonstrated that the blood clotting protein called fibrinogen also regulates MMP-2, an enzyme involved in immunity and in clot formation inside blood vessels. Prolonged MMP-2 inhibition could potentially produce a deficiency state with severe consequences.

12 Jun 2019

Malaria drug may help those with hereditary hearing loss finds study

Researchers have found that anti-malarial drug artemisinin could help patients with genetic or hereditary hearing loss. The study results were published in the latest issue of the journal Proceedings of the National Academy of Sciences (PNAS). The study was titled, “Unconventional secretory pathway activation restores hair cell mechanotransduction in an USH3A model.”

12 Jun 2019

Researchers provide insight into unintended consequence of immune checkpoint inhibitors

Immune checkpoint inhibitors are an emerging type of cancer immunotherapy that uses the immune system to attack cancer cells.

12 Jun 2019

New therapeutic approach utilizes endogenous processes to enhance cardiac repair

Myocardial infarction results in the localized death of the muscle cells that are essential for the heart's pumping function.

12 Jun 2019

UIC researchers describe role of unique pressure-sensing protein in lung edema

Researchers at the University of Illinois at Chicago describe for the first time the role of a unique, pressure-sensing protein in the development of lung edema -- a condition in which chronic high vascular pressure in the lungs causes fluid from the bloodstream to enter the air spaces of the lungs.

11 Jun 2019

Early life adversity and high levels of FKBP5 protein amplify anxiety-like behavior

Researchers continue to dig for molecular clues to better understand how gene-environment interactions influence neuropsychiatric disease risk and resilience.

11 Jun 2019

Smarter, more educated people get a cognitive 'head start', but aren't protected from Alzheimer's

In a search for clues to what may delay or prevent Alzheimer's disease, Johns Hopkins Medicine scientists report that smarter, more educated people aren't protected from the disease, but do get a cognitive "head start" that may keep their minds functioning better temporarily.

From Johns Hopkins Medicine 11 Jun 2019

Smart phone plus nanoscale porous silicon equals simple home medical tests

The simplest home medical tests might look like a deck of various silicon chips coated in special film, one that could detect drugs in the blood, another for proteins in the urine indicating infection, another for bacteria in water and the like

11 Jun 2019

Novel agent shown to have dual mechanism of action to eliminate cancer

Results from a study spearhead by researchers at the Vall d´Hebron Institute of Oncology (VHIO), show that the blockade of the multi-functional cytokine LIF induces tumor-infiltrating T Cells to hone in on and eliminate cancer.

11 Jun 2019

Plant-derived siRNAs could bring a 'green revolution' in RNAi tools and therapeutics

"Green revolution" in the early 1950s, the extensive cultivation of Dwarf Rice solves the food problem in developing countries. At present, chronic infection with hepatitis B virus (HBV) has been a major public health problem.

11 Jun 2019

Complex molecular conversation is key to the establishment of 'hot tumor'

A Ludwig Cancer Research study has deciphered a complex molecular conversation between cancer and immune cells that is key to orchestrating the successful invasion of tumors by T cells that kill cancer cells.

11 Jun 2019

Doctors urge hospitals to reconsider the type of fluids used to treat children with sepsis

Doctors have urged hospitals around the world to reconsider the type of fluids used to treat children gravely ill with sepsis.

11 Jun 2019

Study shows how SIRT1 plays key role in maintaining the regenerative potential of leukemic stem cells

Patients with chronic myeloid leukemia can be treated with tyrosine kinase inhibitors. While these effective drugs lead to deep remission and prolonged survival, primitive leukemia stem cells resist elimination during the remission and persist as a major barrier to cure.

11 Jun 2019

Study suggests therapeutic solutions for pantothenate kinase-associated neurodegeneration

The scientific research team from the Universidad Pablo de Olavide led by doctor José Antonio Sánchez Alcázar has published a new study in the international magazines Molecular Neorubiology and Neural Regeneration Research.

11 Jun 2019

Protein News and Research

Further Reading

Scientists discover weakness in common cold virus

Boehringer Ingelheim and University of Dundee extend collaboration to develop new cancer medicines

Biomarker correlates with prostate cancer aggressiveness and predicts metastasis to bone

Chemists build rich collection of natural product-like macrocycles for drug discovery

Researchers develop new gene-targeted approach to study chronic wasting disease in mice

New research identifies cellular adaptive mechanisms during hypoxic conditions

Fibrinogen a key player in health and disease, says new study

Malaria drug may help those with hereditary hearing loss finds study

Researchers provide insight into unintended consequence of immune checkpoint inhibitors

New therapeutic approach utilizes endogenous processes to enhance cardiac repair

UIC researchers describe role of unique pressure-sensing protein in lung edema

Early life adversity and high levels of FKBP5 protein amplify anxiety-like behavior

Smarter, more educated people get a cognitive 'head start', but aren't protected from Alzheimer's

Smart phone plus nanoscale porous silicon equals simple home medical tests

Novel agent shown to have dual mechanism of action to eliminate cancer

Plant-derived siRNAs could bring a 'green revolution' in RNAi tools and therapeutics

Complex molecular conversation is key to the establishment of 'hot tumor'

Doctors urge hospitals to reconsider the type of fluids used to treat children with sepsis

Study shows how SIRT1 plays key role in maintaining the regenerative potential of leukemic stem cells

Study suggests therapeutic solutions for pantothenate kinase-associated neurodegeneration

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