Protein C News and Research

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Researchers unmask functioning of protein involved in DNA repair during spermatogenesis

Researchers from the Department of Cell Biology, Physiology and Immunology and the Institute for Biotechnology and Biomedicine of the Universitat Autònoma de Barcelona have unmasked the functioning of a protein involved in DNA repair, ATR, in the meiotic recombination process which takes place during the development of spermatocytes - sperm precursor cells- and how inhibiting this protein causes anomalies which block spermatogenesis.

9 Jul 2018

Researchers focus on mechanisms involved in development of non-alcoholic fatty liver disease

One of the lines of research of the UPV/EHU's Lipids & Liver group, which focusses on the mechanisms involved in the development and progression of non-alcoholic fatty liver disease, is achieving significant advances in a range of aspects; these include the identification of proteins that alter the metabolic pathways in the development and progression of liver disease, and even cancer, and the seeking of targets to enable the disease to be reversed.

9 Jul 2018

Protein complex that helps shape destiny of developing T cells identified

Like a mentor helping medical students choose between specialties, a protein complex helps shape the destiny of developing T cells, St. Jude Children's Research Hospital scientists have reported.

9 Jul 2018

Savory foods can cause changes in the brain that promote healthy eating behaviors

Researchers have found that consuming a broth rich in umami--or savory taste--can cause subtle changes in the brain that promote healthy eating behaviors and food choices, especially in women at risk of obesity.

9 Jul 2018

Study uncovers how a sticky protein promotes activity of estrogen in breast cancer cells

New research uncovers how a sticky protein called fibronectin promotes the activity of estrogen in breast cancer cells.

9 Jul 2018

Scientists discover new target to treat blood vessel damage in diabetes

In diabetes, both the tightly woven endothelial cells that line our blood vessels and the powerhouses that drive those cells start to come apart as early steps in the destruction of our vasculature.

9 Jul 2018

Study finds common risk gene for both job-related exhaustion in shift workers and Alzheimer's

A Finnish study published in the respected SLEEP journal shows that a variation in the melatonin receptor 1A (MTNR1A) gene is linked to the risk of Alzheimer's disease in the elderly.

6 Jul 2018

Survival mechanisms of polar fish inspire revolutionary method to 'freeze' bacteria

The survival mechanisms of polar fish have led scientists at the University of Warwick to develop of a revolutionary approach to 'freeze' bacteria.

6 Jul 2018

Researchers use precision genomics to search genetic mutations causing accelerated aging

Mayo Clinic researchers are using precision genomics to search for undiscovered, inheritable genetic mutations that cause accelerated aging. In a study recently published in Mayo Clinic Proceedings, researchers conducted a study assessing 17 patients with short telomere syndromes - rare conditions that result in premature DNA and cellular deterioration.

6 Jul 2018

Researchers question previous understanding of Parkinson's disease

Parkinson's disease was first described by a British doctor more than 200 years ago. The exact causes of this neurodegenerative disease are still unknown.

6 Jul 2018

Study finds mechanism by which amyloid beta protects the brain from herpes infection

A Massachusetts General Hospital study has found the mechanism by which amyloid beta - the protein deposited into plaques in the brains of patients with Alzheimer's disease - protects from the effects of herpes viruses commonly found in the brain.

6 Jul 2018

Irregular metabolism of branched-chain amino acids may cause progression of type 2 diabetes

In the U.S., about five out of 100 expectant mothers develop gestational diabetes mellitus, a temporary form of diabetes in which hormonal changes disrupt insulin function.

6 Jul 2018

Targeting multiple proteins may be key to treat neurodegenerative disorders

Nearly all major neurodegenerative diseases - from Alzheimer's to Parkinson's - are defined and diagnosed by the presence of one of four proteins that have gone rogue: tau, amyloid-beta, alpha-synuclein, or TDP-43.

6 Jul 2018

Pneumococcal genes predict course of disease

Pneumococcus is an important cause of pneumonia, sepsis and meningitis. This bacterium commonly resides in the nasal cavity.

6 Jul 2018

Stabilizing dysfunctional endothelial cells reverses cellular dysfunction in rat model of SVD

Researchers have discovered that stabilizing dysfunctional endothelial cells with approved drugs reverses cellular dysfunction in a rat model of cerebral small vessel disease, hinting towards a new therapeutic approach for the treatment of vascular dementia.

5 Jul 2018

New small molecules offer promising new way to treat autoinflammatory diseases

EPFL scientists have discovered two small-molecule compound series that can effectively block a central pathway of the innate immune system, offering a promising new way for treating autoinflammatory diseases.

4 Jul 2018

Scientists develop new method to view proteins inside human cells

Scientists at the University of Warwick have created a new way to view proteins that are inside human cells.

4 Jul 2018

Research elucidates maturation of cancer-causing miRNAs

An international research team led by Helmholtz Zentrum München, Technical University of Munich and the University of Edinburgh has used an integrated structural biological approach to elucidate the maturation of a cancer-causing microRNA in gene regulation.

4 Jul 2018

Study explains why men are more at risk for neurodevelopmental disorders

A new study has shed light on the reason why males are more at risk than females for neurodevelopmental disorders such as autism, schizophrenia and ADHD.

4 Jul 2018

SATB1 protein important for maintaining pluripotency of hematopoietic stem cells

Osaka University scientists demonstrate that SATB1 is important for maintaining pluripotency of hematopoietic stem cells

4 Jul 2018

Protein C News and Research

Researchers unmask functioning of protein involved in DNA repair during spermatogenesis

Researchers focus on mechanisms involved in development of non-alcoholic fatty liver disease

Protein complex that helps shape destiny of developing T cells identified

Savory foods can cause changes in the brain that promote healthy eating behaviors

Study uncovers how a sticky protein promotes activity of estrogen in breast cancer cells

Scientists discover new target to treat blood vessel damage in diabetes

Study finds common risk gene for both job-related exhaustion in shift workers and Alzheimer's

Survival mechanisms of polar fish inspire revolutionary method to 'freeze' bacteria

Researchers use precision genomics to search genetic mutations causing accelerated aging

Researchers question previous understanding of Parkinson's disease

Study finds mechanism by which amyloid beta protects the brain from herpes infection

Irregular metabolism of branched-chain amino acids may cause progression of type 2 diabetes

Targeting multiple proteins may be key to treat neurodegenerative disorders

Pneumococcal genes predict course of disease

Stabilizing dysfunctional endothelial cells reverses cellular dysfunction in rat model of SVD

New small molecules offer promising new way to treat autoinflammatory diseases

Scientists develop new method to view proteins inside human cells

Research elucidates maturation of cancer-causing miRNAs

Study explains why men are more at risk for neurodevelopmental disorders

SATB1 protein important for maintaining pluripotency of hematopoietic stem cells

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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