Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Cornell scientists discover new 'jumping' superbug gene

While sifting through the bacterial genome of salmonella, Cornell University food scientists discovered mcr-9, a new stealthy, jumping gene so diabolical and robust that it resists one of the world's few last-resort antibiotics.

7 May 2019

Scientific research articles show that imipridones target mitochondrial function in cancer cells

Oncoceutics, Inc. announced the publication of two scientific research articles demonstrating that members of the imipridone family ONC201 and ONC212 directly activate a mitochondrial protease called caseinolytic protease P.

7 May 2019

Long-standing immunosuppressive drug reduces Zika birth defects in mice

In experiments with pregnant mice infected with the Zika virus, Johns Hopkins Medicine researchers report they have successfully used a long-standing immunosuppressive drug to diminish the rate of fetal deaths and birth defects in the mice's offspring.

From Johns Hopkins Medicine 7 May 2019

Researchers develop new molecule that binds to the cerebrovascular system

Brazilian and US researchers have developed a molecule called FRW that, in tests with mice, proved capable of binding to blood vessels in the brain but not in other organs when injected into the bloodstream.

7 May 2019

Research in preclinical models suggests promising anti-HIV-1 vaginal microbicide

A vaginal microbicide that could prevent sexual transmission of HIV-1 in women has tremendous potential for saving lives and helping staunch an epidemic.

7 May 2019

Skin-related stem cells could be used to regenerate vital part of the nervous system

Neurodegenerative diseases like multiple sclerosis affect millions of people worldwide and occur when parts of the nervous system lose function over time.

7 May 2019

Researchers develop a new approach to targeting tumors and metastases

The spread of malignant cells from an original tumor to other parts of the body, known as metastasis, is the main cause of cancer deaths worldwide.

7 May 2019

Finding potential treatments for autoimmune diseases

More than 50 million Americans are affected by an autoimmune disease, with women at an increased risk for developing one.

7 May 2019

Researchers discover new role for LRS protein in muscle repair

Researchers report that a protein known to be important to protein synthesis also influences muscle regeneration and regrowth in an unexpected manner.

7 May 2019

New drug successfully lowers levels of toxic protein that causes Huntington disease

An international clinical trial has found that a new drug for Huntington disease is safe, and that treatment with the drug successfully lowers levels of the abnormal protein that causes the debilitating disease in patients.

7 May 2019

Form drives function in cancer proliferation, UTSW study finds

A new study finds that the protein responsible for the crawling movements of cells also drives the ability of cancer cells to grow when under stress.

6 May 2019

Low oxygen levels harm specific cells in the developing brain

Low oxygen levels are a well-known cause of brain injury in premature babies. But the mechanism by which low oxygen hurts the developing human brain has been unclear.

6 May 2019

Soy protein reduces LDL cholesterol, study finds

Soy protein has the ability to lower cholesterol by a small but significant amount, suggests a new study led by St. Michael's Hospital in Toronto.

6 May 2019

Messenger cells hold key to better bone healing

How do bones heal, and how could they heal better? The answer to these questions may lie in a newly discovered population of "messenger" cells, according to a recent USC Stem Cell study published in the journal eLife.

6 May 2019

Coffee, sugary drinks, or alcohol? It's in your genes.

Researchers have discovered that choosing to consume alcohol, coffee, and sugar-sweetened drinks may be due to hertitable genetic variants.

6 May 2019

Study finding promises new perspectives for treatment of Type 2 endometrial cancer

Brazilian scientists identify the predominant presence of a truncated variant of the p53 protein in amyloid aggregates in endometrial cancer cells. Such structures are related to the progression of this tumor.

3 May 2019

New two-tier method can enable early-stage detection of Alzheimer’s

Using current techniques, Alzheimer's disease, the most frequent cause of dementia, can only be detected once the typical plaques have formed in the brain.

3 May 2019

Discovery of small-molecule inhibitors could enable precise control over CRISPR-Cas9 genome editing

The discovery of the first small-molecule inhibitors of the Streptococcus pyogenes Cas9 (SpCas9) protein could enable more precise control over CRISPR-Cas9-based genome editing, researchers report May 2 in the journal Cell.

3 May 2019

Scientists describe how cells 'decide' between pluripotency and differentiation

Induced pluripotent stem cells can turn into any type of cell in the body or remain in their original form. In the current edition of Molecular Cell, scientists from the Helmholtz Zentrum München describe how cells “decide” which of these two directions to take.

3 May 2019

Novel chemical probe enables live imaging of brain immune cells

Researchers in South Korea and Singapore have, for the first time, developed a chemical probe that enables live-imaging of a type of immune cells in the brain, known as microglia, in a live animal brain.

3 May 2019