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UK’s pace of decline in mortality among children and young adults falls behind EU15+ average

The UK has failed to match the gains made in reducing deaths among children and young adults by 17 other high-income countries in the European Union, Australia, Canada, and Norway (EU15+) in the 38 years since 1970.

13 Jun 2014

Use of opioid linked to higher levels of dissatisfaction following spine surgery

A new study appearing in the Journal of Bone and Joint Surgery (JBJS) links the use of opioid pain relievers (prescription medications, such as Percocet) to less improvement and higher levels of dissatisfaction following spine surgery.

13 Jun 2014

Excessive abuse of alcohol causes structural damage at molecular level to the brain

Joint research between the University of the Basque Country (UPV/EHU) and the University of Nottingham has identified, for the first time, the structural damage caused at a molecular level to the brain by the chronic excessive abuse of alcohol.

13 Jun 2014

NSF awards nearly $200,000 to make environmentally friendly field analyzer

The National Science Foundation has awarded nearly $200,000 to two University of Texas at Arlington researchers teaming with a private company to make an affordable, environmentally friendly field analyzer for arsenic levels in water.

13 Jun 2014

U.S. cancer survivors face economic burdens due to growing medical costs, productivity losses

U.S. cancer survivors face significant economic burdens due to growing medical costs, missed work, and reduced productivity, according to a study by the Centers for Disease Control and Prevention in today's Morbidity and Mortality Weekly Report.

12 Jun 2014

BRI researchers use tetramer technology to find T cells that drive rheumatoid arthritis

Researchers at Benaroya Research Institute at Virginia Mason used cutting-edge tetramer technology developed at BRI to find the T cells that drive rheumatoid arthritis (RA). "By using tetramer technology, we were able to examine whether T cells in people with rheumatoid arthritis were increased in number or were unique in other ways," says BRI Associate Director Jane Buckner, MD, who led the study with BRI Tetramer Core Laboratory Manager Eddie James, PhD.

12 Jun 2014

Osteoarthritis patients treated with SoluMatrix meloxicam report greater pain relief

Iroko Pharmaceuticals, LLC, a global specialty pharmaceutical company dedicated to advancing the science of analgesia, today will present Phase 3 results that showed osteoarthritis (OA) patients treated with investigational SoluMatrix meloxicam 5 mg and 10 mg, a low dose nonsteroidal anti-inflammatory drug (NSAID), reported significantly greater pain relief compared with placebo.

12 Jun 2014

One-third of PsA patients not receiving adalimumab doses to achieve optimal clinical benefit

Data presented today at the European League Against Rheumatism Annual Congress showed that a significant number of patients with psoriatic arthritis (PsA) were not receiving doses of the tumour necrosis factor-alpha (TNFα) inhibitor adalimumab necessary to achieve optimal clinical benefit.

12 Jun 2014

Aston University plans for new Medical School to train new generation of doctors

Aston University (UK) has announced plans for a new Medical School which will train a new generation of doctors in Birmingham and the West Midlands.

12 Jun 2014

Targeted brain training can help improve cognitive performance in teens with traumatic brain injuries

Traumatic brain injuries from sports, recreational activities, falls or car accidents are the leading cause of death and disability in children and adolescents. While previously it was believed that the window for brain recovery was at most one year after injury, new research from the Center for BrainHealth at The University of Texas at Dallas published online today in the open-access journal Frontiers in Neurology shows cognitive performance can be improved to significant degrees months, and even years, after injury, given targeted brain training.

12 Jun 2014

DNA methylation identified as potential anti-TNF response biomarker for RA

DNA methylation has been identified as a potential biomarker of response to etanercept and adalimumab in patients with rheumatoid arthritis (RA) according to preliminary results from one of the largest methylome-wide investigations of treatment response to anti-TNF therapies.

12 Jun 2014

Exercise transiently suppresses inflammation in rheumatic disease

Research findings presented today at the European League Against Rheumatism Annual Congress suggest that exercise transiently suppresses local and systemic inflammation, reinforcing the beneficial effects of exercise and the need for this to be regular in order to achieve clinical efficacy in rheumatic disease.

12 Jun 2014

Back App: A training apparatus for Sitting Disease

Scientific research is increasingly showing strong links between spending too much time sitting and the development of severe long and short term health problems.

12 Jun 2014

TxCell receives Certificate of GMP compliance for cell therapy manufacturing facility in France

TxCell SA, a biotechnology company developing innovative, personalized cell-based immunotherapies using antigen specific regulatory T-cells (Ag-Tregs) for severe chronic inflammatory and autoimmune diseases, announces today that it has been granted Certificate of Good Manufacturing Practice (GMP) compliance for its cell therapy manufacturing facility in Besançon, France.

12 Jun 2014

Obese patients with rheumatoid arthritis have higher disease activity scores

A new study presented today at the European League Against Rheumatism Annual Congress showed that obese patients with rheumatoid arthritis (RA) have higher DAS (disease activity) scores than non-obese patients, irrespective of their disease stage.

12 Jun 2014

Otsuka Pharmaceutical begins tolvaptan Phase 3b study in patients with ADPKD

Otsuka Pharmaceutical Development & Commercialization, Inc., announced today that patient enrollment has begun for a new Phase 3b study of tolvaptan for adult patients with autosomal dominant polycystic kidney disease (ADPKD), the most common, life-threatening, inherited genetic kidney disorder.

11 Jun 2014

Brain structure linked to psychosis symptoms

A study of patients across the psychosis spectrum supports an association between brain structure and psychosis symptoms.

11 Jun 2014

‘Real-world’ ambrisentan data unveiled

The use of and outcomes with ambrisentan in clinical practice are different to those in clinical trials, reflecting different patient characteristics in the “real world”, say researchers.

11 Jun 2014

Celgene: OTEZLA phase III study for psoriatic arthritis meets primary endpoint

Celgene International Sàrl, a wholly-owned subsidiary of Celgene Corporation (NASDAQ:CELG), today announced results of additional analyses from the phase III clinical trials of OTEZLA, the Company's oral, selective inhibitor of phosphodiesterase 4 (PDE4).

11 Jun 2014

First Edition: June 11, 2014

Today's headlines include a range of stories about the upset of House Majority Leader Eric Cantor -- a Virginia primary election shocker -- as well as continuing coverage of health law implementation issues and congressional responses to the VA's health care troubles.

11 Jun 2014

Chronic News and Research

UK’s pace of decline in mortality among children and young adults falls behind EU15+ average

Use of opioid linked to higher levels of dissatisfaction following spine surgery

Excessive abuse of alcohol causes structural damage at molecular level to the brain

NSF awards nearly $200,000 to make environmentally friendly field analyzer

U.S. cancer survivors face economic burdens due to growing medical costs, productivity losses

BRI researchers use tetramer technology to find T cells that drive rheumatoid arthritis

Osteoarthritis patients treated with SoluMatrix meloxicam report greater pain relief

One-third of PsA patients not receiving adalimumab doses to achieve optimal clinical benefit

Aston University plans for new Medical School to train new generation of doctors

Targeted brain training can help improve cognitive performance in teens with traumatic brain injuries

DNA methylation identified as potential anti-TNF response biomarker for RA

Exercise transiently suppresses inflammation in rheumatic disease

Back App: A training apparatus for Sitting Disease

TxCell receives Certificate of GMP compliance for cell therapy manufacturing facility in France

Obese patients with rheumatoid arthritis have higher disease activity scores

Otsuka Pharmaceutical begins tolvaptan Phase 3b study in patients with ADPKD

Brain structure linked to psychosis symptoms

‘Real-world’ ambrisentan data unveiled

Celgene: OTEZLA phase III study for psoriatic arthritis meets primary endpoint

First Edition: June 11, 2014

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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