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Researchers identify new factors that can predict breast cancer recurrence

Genetics and other factors that can determine if a woman is at risk for a recurrence of breast cancer have been identified by investigators at Georgetown Lombardi Comprehensive Cancer Center, providing new research avenues for preventing a new tumor from developing.

22 Apr 2022

Discovering Genetic Variants that Significantly Predispose People to Critical COVID-19

We speak with postdoctoral researcher Erola Pairo-Castineira about her recent work which aimed to find the genetic factors that may predispose individuals to critical COVID-19 and learn how COVID-19 affects cells in the body.

22 Apr 2022

Hybrid alphavirus-SARS-CoV-2 pseudovirus system rapidly measures neutralizing antibodies

Do a person's antibodies work to block the COVID-19 virus from infecting one's system? Are these antibodies also capable of blocking emerging variants such as the omicrons?

21 Apr 2022

UNIGE biologists discover a factor that explains breast cancer metastases to the bones

A team of biologists led by UNIGE has discovered, for breast cancer, a factor that explains the spread of metastases to the bones.

21 Apr 2022

Scientists identify innovative treatment approach for arterial thromboses

Scientists have shown in an animal model that the CXCL12 messenger could be suitable as a target structure for the treatment of blood-clotting disorders.

21 Apr 2022

Investigating the impact of SARS-CoV-2 Omicron spike mutations

Researchers investigated the impact of amino acid substitutions of SARS-CoV-2 Omicron on spike protein function, processing, and neutralization susceptibility.

20 Apr 2022

Study evaluates the ocular tropism and the possible ocular transmission of SARS-CoV-2 in animal models

Researchers demonstrated ocular tropism of SARS-CoV-2 through neuronal invasion in transgenic mice with hACE2 expression.

20 Apr 2022

Novel targets for treating sorafenib-resistant hepatocellular carcinoma found using CRISPR-Cas9 screening

This study is led by Xiujun Cai (Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine). Professor Xiujun Cai's research team screened the whole genome of hepatocellular carcinoma cells (HepG2) through CRISPR / cas9 system under sorafenib treatment, and screened the dominant gene in sorafenib resistance.

20 Apr 2022

Novel approach to identify targets for Wolbachia-based dengue control

Dengue is the most widespread mosquito-borne disease in the world, and to date, there are no medical treatments for people suffering from this disease.

19 Apr 2022

Researchers discover a novel signaling pathway that defines interferon responses in blood cancers

Northwestern Medicine investigators have discovered a novel signaling pathway activated by interferons, a group of immune system proteins, that suppresses the anti-tumor response of interferons in patients with a particular type of blood cancer, according to findings published in Nature Communications.

19 Apr 2022

Scientists precisely define the ‘identity card’ of pancreatic endocrine cells

The pancreas is a key metabolic regulator. When pancreatic beta cells cease producing enough insulin, blood sugar levels rise dangerously — a phenomenon known as hyperglycemia — thus triggering diabetes.

19 Apr 2022

New, longest documented case of persistent acute SARS-CoV-2 infection

Researchers describe a 16-month-old case of SARS-CoV-2 infection in an immunocompromised individual.

18 Apr 2022

Solid bone marrow aspirates may be a promising therapeutic approach for promoting wound healing

A new study compares the regenerative potential of blood/bone marrow aspirate concentrates obtained from arterial blood, venous blood, and bone marrow aspirate. The study, conducted in rabbits, is reported in the peer-reviewed journal Tissue Engineering Part A.

18 Apr 2022

Addition of left-handed chiral gold nanoparticles can enhance vaccine efficacy by more than 25%

Vaccines can be made over 25% more effective by adding left-handed chiral gold nanoparticles as adjuvants, according to a study by an international collaboration in which Brazilian researchers took part. An article reporting the results is published in Nature.

18 Apr 2022

in vitro News and Research

Researchers identify new factors that can predict breast cancer recurrence

Discovering Genetic Variants that Significantly Predispose People to Critical COVID-19

Hybrid alphavirus-SARS-CoV-2 pseudovirus system rapidly measures neutralizing antibodies

UNIGE biologists discover a factor that explains breast cancer metastases to the bones

Scientists identify innovative treatment approach for arterial thromboses

Investigating the impact of SARS-CoV-2 Omicron spike mutations

Study evaluates the ocular tropism and the possible ocular transmission of SARS-CoV-2 in animal models

Novel targets for treating sorafenib-resistant hepatocellular carcinoma found using CRISPR-Cas9 screening

Novel approach to identify targets for Wolbachia-based dengue control

Researchers discover a novel signaling pathway that defines interferon responses in blood cancers

Scientists precisely define the ‘identity card’ of pancreatic endocrine cells

New, longest documented case of persistent acute SARS-CoV-2 infection

Solid bone marrow aspirates may be a promising therapeutic approach for promoting wound healing

Addition of left-handed chiral gold nanoparticles can enhance vaccine efficacy by more than 25%

Scientists unravel the complex workings of the circadian rhythm in cyanobacteria

Study predicts that different statins exhibit divergent effects on host response to SARS-CoV-2 infection

SARS-CoV-2 infection patterns in olfactory epithelium

Role of cGAS-STING in SARS-CoV-2 infection

Cell’s production of lipids can be a key factor in determining cell fate

Recent advances in non-viral nano-vector delivery of CRISPR/Cas9 genome editing payloads

Driving innovation in drug discovery with in vitro biology solutions eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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