Syndrome News and Research

RSS

Chronic dry eye syndrome after LASIK

Scientists at Schepens Eye Research Institute have found that people with a certain low level of tear production are more likely to develop chronic dry eye syndrome after LASIK (laser-assisted in situ keratomileusis), laser refractive surgery to correct near- and far-sightedness than those with more plentiful tears.

4 Mar 2008

Bardet-Biedl syndrome provides clues on obesity, blood pressure

University of Iowa researchers have found a clue about how resistance to the hormone leptin might disrupt the brain signals that tell the body when to stop eating.

4 Mar 2008

Mouse model tightly matches pediatric tumor syndrome, will speed drug hunt

Frustrated by the slow pace of new drug development for a condition that causes pediatric brain tumors, a neurologist at Washington University School of Medicine in St. Louis decided to try to fine-tune the animal models used to test new drugs.

3 Mar 2008

Snoring linked to cardiovascular disease, increased health-care utilization

Loud snoring with breathing pauses is associated with an increased risk of cardiovascular disease and increased health care utilization, according to a study published in the March 1 issue of the journal SLEEP.

3 Mar 2008

Treatment with methylphenidate helps adults with ADHD sleep

Treatment with methylphenidate (MPH) appears to have beneficial effects on sleep parameters in adults with ADHD, including increased sleep efficiency and a feeling of improved restorative value of sleep, according to a study published in the March 1 issue of the journal SLEEP.

3 Mar 2008

Adult stem cell changes underlie Hutchinson-Gilford Progeria syndrome associated with accelerated aging

Adult stem cells may provide an explanation for the cause of a Hutchinson-Gilford Progeria Syndrome (HGPS), a rare disease that causes premature aging in children, according to researchers at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH).

3 Mar 2008

Researchers investigate predictors for sickle-cell-anemia complications

Researchers at UT Southwestern Medical Center have determined that the level, or saturation, of oxygen in blood could be used to identify children with sickle cell anemia who are at an increased risk of stroke.

1 Mar 2008

New discovery on programmed cell death

Investigators at St. Jude Children's Research Hospital have discovered a dance of proteins that protects certain cells from undergoing apoptosis, also known as programmed cell death. Understanding the fine points of apoptosis is important to researchers seeking ways to control this process.

1 Mar 2008

NIDDK releases new awareness series on diabetes, digestive diseases and kidney and urologic diseases

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) has announced the release of new health information to raise awareness about diabetes, digestive diseases, and kidney and urologic diseases among people not yet diagnosed with these illnesses.

1 Mar 2008

AstraZeneca submits sNDA for SEROQUEL XR for treatment of major depressive disorder

AstraZeneca has announced the submission of a supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration (FDA) for once- daily SEROQUEL XR (quetiapine fumarate) Extended-Release Tablets to seek approval for the treatment of major depressive disorder (MDD) as monotherapy, adjunct therapy, and maintenance therapy in adult patients.

1 Mar 2008

Potential target to treat deadly bloodstream infections

Researchers at the University of Illinois at Chicago have discovered a possible target to treat bloodstream bacterial infections.

28 Feb 2008

Low-intensity exercise reduces fatigue symptoms by 65 percent

Sedentary people who regularly complain of fatigue can increase their energy levels by 20 percent and decrease their fatigue by 65 percent by engaging in regular, low intensity exercise, according to a new University of Georgia study.

28 Feb 2008

Lilly knocked back by FDA on Zyprexa for schizophrenia treatment

Eli Lilly and Company has received a not approvable letter from the U.S. Food and Drug Administration for Zyprexa long-acting injection (olanzapine LAI) for the treatment and maintenance treatment of schizophrenia in adults, the company announced.

28 Feb 2008

Discovery of potential drug targets for sepsis

"We have identified a key connection of signaling pathways in the cascade of events leading to sepsis. This defines a crucial point where the immune system spirals out of control to cause severe sepsis and where there is an opportunity for therapeutic intervention," says Scripps Research Professor Wolfram Ruf, who led the research with his postdoctoral fellow Frank Niessen.

28 Feb 2008

FDA approves Arcalyst for treatment of rare inflammatory syndromes

The U.S. Food and Drug Administration has approved a drug to help ease the suffering faced by those with certain chronic inflammatory diseases.

28 Feb 2008

Exercise and caloric restriction may be treatment method for metabolic syndrome

Published in the March/April issue of AJLM, the article, written by Peter M. Janiszewski, MSc, Travis J. Saunders BSc, and Robert Ross, PhD, at Queen's University, reviews existing evidence that exercise and caloric restriction can be a valid treatment strategy for metabolic syndrome.

28 Feb 2008

Are cataract rates on the decline?

Should glaucoma patients seeking alternative therapies trust what they find online? Are seatbelts still important to protect eyes in auto accidents, now that most cars have airbags? What's the connection between hearing loss and one form of glaucoma? These are among the topics explored in the March 2008 issue of Ophthalmology, the journal of the American Academy of Ophthalmology.

28 Feb 2008

Children's Hospital 1 of 10 pediatric hospitals in US selected to study liver disease in kids

Children's Hospital of Pittsburgh of UPMC has been selected to join an effort among select centers in the United States and Canada to collect and study information necessary to understand the possible causes and treatment of a destructive liver disease called primary sclerosing cholangitis (PSC).

27 Feb 2008

Abbott receives approval for HUMIRA (Adalimumab) for polyarticular juvenile idiopathic arthritis

Abbott has announced that it has received U.S. Food and Drug Administration (FDA) approval to market HUMIRA (adalimumab) as a treatment to reduce signs and symptoms of moderately to severely active polyarticular juvenile idiopathic arthritis (JIA) in patients four years of age and older.

26 Feb 2008

Unusual case of upper obstructive syndrome

Aorto-duodenal fistulae (ADF) are the most frequent aorto-enteric fistulae (80%) and the most frequent presenting sign of ADF is upper gastrointestinal bleeding (UGI).

25 Feb 2008