Microbiology News and Research

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COVID-19 vaccine candidate shows potent immune response

A COVID-19 vaccine candidate that underwent extensive preclinical testing at the University of Alabama at Birmingham this spring and summer shows potent preclinical immune responses - including several that distinguish it from other COVID-19 vaccine approaches - according to a preprint deposited in the BioRxiv repository this week.

13 Oct 2020

Powerful antimicrobial molecules engineered from toxic proteins in wasp venom

A team led by scientists in the Perelman School of Medicine at the University of Pennsylvania has engineered powerful new antimicrobial molecules from toxic proteins found in wasp venom.

12 Oct 2020

Virginia Tech to build a cyberinfrastructure for wastewater antibiotic-resistant gene monitoring

Antibiotic resistance is a grand challenge of the 21st century. According to the U.S. Centers for Disease Control and Prevention, antibiotic resistance rates are increasing globally, with an estimated 35,000 related deaths per year in the United States in 2019, compared to 23,000 in 2013.

8 Oct 2020

Detection of SARS-CoV-2 viral persistence in built environments

In a recent paper in an open-access journal, mSystems, published by The American Society for Microbiology, Ceth W. Parker et al. show challenges in recovering the virus, change in infectivity, and the case of viral persistence in built environments.

8 Oct 2020

Simple sugar in human breast milk can promote myelin repair in multiple sclerosis patients

N-acetylglucosamine, a simple sugar found in human breast milk and sold as an over-the-counter dietary supplement in the United States, promotes myelin repair in mouse models and correlates with myelination levels in multiple sclerosis patients according to a new University of California, Irvine-led study.

8 Oct 2020

New biomarker may help identify patients at risk for graft-versus-host disease after stem cell transplants

A recent report published in Science Translational Medicine by MUSC Hollings Cancer Center investigator Sophie Paczesny, M.D., Ph.D., sheds light on immune cell biomarkers that may reveal which patients are most at risk for graft-versus-host disease (GVHD), a life-threatening condition that can arise after hematopoietic stem cell transplantation (HSCT) for treatment of liquid cancers such as leukemia.

7 Oct 2020

Endocannabinoids in the body can help fight intestinal infections

Endocannabinoids, signaling molecules produced in the body that share features with chemicals found in marijuana, can shut down genes needed for some pathogenic intestinal bacteria to colonize, multiply, and cause disease, new research led by UT Southwestern scientists shows.

7 Oct 2020

Multi-center Phase I study of anti-VISTA opens for patient enrollment

Dartmouth and Dartmouth-Hitchcock Norris Cotton Cancer Center will serve as one of the lead institutions for a new multi-center clinical trial of anti-VISTA, now open and recruiting for patient enrollment.

7 Oct 2020

Native freshwater bacteria can destroy toxins produced during harmful algal blooms

Searching for new ways to address the growing threat to drinking water in northwest Ohio and across the globe, Dr. Jason Huntley discovered that native freshwater bacteria can destroy toxins produced during harmful algal blooms.

7 Oct 2020

People infected with other types of coronaviruses may have less severe COVID-19 infection

Being previously infected with a coronaviruses that cause the "common cold" may decrease the severity of severe acute respiratory syndrome coronavirus (SARS-CoV-2) infections, according to results of a new study

7 Oct 2020

Study determines frequency and patterns of T-cell escape mutations in HIV patients undergoing antiretroviral therapy

Immune cells that can recognize residual HIV-infected cells in people living with HIV (PLWH) who take antiretroviral therapy (ART) remain active for years, says a new study published today in eLife.

7 Oct 2020

Study may explain why cannabis plant can reduce symptoms of various bowel conditions

7 Oct 2020

IL-21 protein is a major part of immune response to chronic infections in the central nervous system

Researchers at Penn State College of Medicine now better understand the role of a protein, interleukin-21 (IL-21), in the immune system response to infections in the nervous system.

6 Oct 2020

Researchers discover a new, rapid method to fabricate nanoparticles

Northwestern University researchers are casting a net for nanoparticles.The team has discovered a new, rapid method for fabricating nanoparticles from a simple, self-assembling polymer.

6 Oct 2020

Thiopurines could help stop viral replication in human coronaviruses

Researchers from the Department of Microbiology & Immunology, Dalhousie University, University of Calgary, and Department of Biochemistry and Molecular Biology, University of British Columbia, Canada, worked with human coronaviruses in cell cultures to look for drugs that might prevent accumulation and replication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

6 Oct 2020

Understanding how the malaria parasite can withstand fever's heat

Even when a person suffering from malaria is burning up with fever and too sick to function, the tiny blood-eating parasites lurking inside them continue to flourish, relentlessly growing and multiplying as they gobble up the host's red blood cells.

5 Oct 2020

Study reveals how immune cells sacrifice themselves to help fight off infections

Whether flu or coronavirus, it can take several days for the body to ramp up an effective response to a viral infection.

1 Oct 2020

Scientists map genetic networks that control the biology of regulatory T cells

Unlike most T cells, which launch immune responses against foreign molecules, regulatory T cells are the peacekeepers of the human immune system, damping down inflammatory reactions when they're not needed.

1 Oct 2020

In-depth analysis of coronavirus genome sequence in Norfolk identifies hidden outbreaks

An in-depth analysis of the genome sequence of coronavirus circulating in Norfolk, UK by researchers at the Quadram Institute and University of East Anglia has mapped the spread of the virus, identified hidden outbreaks and provided insights into the effectiveness of interventions to stop its spread.

1 Oct 2020

Investigational mRNA vaccine to prevent SARS-CoV-2 shows promise in older adults

A Phase 1 trial of an investigational mRNA vaccine to prevent SARS-CoV-2 infection has shown that the vaccine is well-tolerated and generates a strong immune response in older adults.

30 Sep 2020

Microbiology News and Research

COVID-19 vaccine candidate shows potent immune response

Powerful antimicrobial molecules engineered from toxic proteins in wasp venom

Virginia Tech to build a cyberinfrastructure for wastewater antibiotic-resistant gene monitoring

Detection of SARS-CoV-2 viral persistence in built environments

Simple sugar in human breast milk can promote myelin repair in multiple sclerosis patients

New biomarker may help identify patients at risk for graft-versus-host disease after stem cell transplants

Endocannabinoids in the body can help fight intestinal infections

Multi-center Phase I study of anti-VISTA opens for patient enrollment

Native freshwater bacteria can destroy toxins produced during harmful algal blooms

People infected with other types of coronaviruses may have less severe COVID-19 infection

Study determines frequency and patterns of T-cell escape mutations in HIV patients undergoing antiretroviral therapy

Study may explain why cannabis plant can reduce symptoms of various bowel conditions

IL-21 protein is a major part of immune response to chronic infections in the central nervous system

Researchers discover a new, rapid method to fabricate nanoparticles

Thiopurines could help stop viral replication in human coronaviruses

Understanding how the malaria parasite can withstand fever's heat

Study reveals how immune cells sacrifice themselves to help fight off infections

Scientists map genetic networks that control the biology of regulatory T cells

In-depth analysis of coronavirus genome sequence in Norfolk identifies hidden outbreaks

Investigational mRNA vaccine to prevent SARS-CoV-2 shows promise in older adults

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