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UTSW study reveals mechanisms underlying development of Sonic Hedgehog medulloblastoma

A delicate balance during brain development could have profound implications for understanding and treating medulloblastoma, the most common malignant brain tumor affecting children.

29 Mar 2018

Study identifies potential genetic link in sudden infant death syndrome

Rare genetic mutations associated with impairment of the breathing muscles are more common in children who have died from sudden infant death syndrome (also known as ‘cot death’) than in healthy controls, suggesting a possible genetic element of the disorder, according to a case-control study in the UK and USA published in The Lancet.

29 Mar 2018

Seven ways to eat foods that have positive impact on budget and health

Think eating healthy foods is too expensive to try? Think again: A recent study showed that a healthy diet costs only about $1.50 more per day per person than its less healthy counterpart.

28 Mar 2018

High levels of humanin protein found in placenta of women who delivered low-birthweight babies

For the first time, UCLA scientists have discovered higher levels of a protein called humanin in the placenta tissue of women who give birth to severely underweight infants.

28 Mar 2018

Research pinpoints potential weak link in bacterial wall-building protein

The wall that surrounds bacteria to shield them from external assaults has long been a tantalizing target for drug therapies. Indeed, some of modern medicine's most reliable antibiotics disarm harmful bacteria by disrupting the proteins that build their protective armor.

28 Mar 2018

Phase I clinical trial of HIV vaccines to begin in the U.S.

A Phase I clinical trial testing the safety of vaccines that might have the potential to prevent HIV infection will begin this month at four sites in the United States, marking the latest step in a three-decade quest at UMass Medical School to harness the power of DNA vaccines in addressing a major global health threat.

28 Mar 2018

Study uncovers more complex, elaborate role for the body’s macromolecular complexes

Scientists at the National Institute on Drug Abuse Intramural Research Program have uncovered evidence that shows a more complex and elaborate role for the body's hard-working G protein-coupled receptors than previously thought, suggesting a conceptual advance in the fields of biochemistry and pharmacology.

28 Mar 2018

New test detects Zika antibodies with high specificity

A test that detects antibodies against Zika virus in samples of blood serum with high specificity - and hence a low risk of cross-reaction with related microorganisms such as dengue virus - is set to come on to the Brazilian market before 2018 is out.

28 Mar 2018

Biophysical mechanism involving spaghetti-like proteins helps cells avoid 'data breaches'

Cells can avoid "data breaches" when letting signaling proteins into their nuclei thanks to a quirky biophysical mechanism involving a blur of spaghetti-like proteins, researchers from the Rockefeller University and the Albert Einstein College of Medicine have shown.

28 Mar 2018

Simple bedside test may help doctors diagnose certain degenerative brain diseases

A simple bedside test that matches a change in heart rate with a drop in blood pressure after a patient stands may help doctors diagnose certain degenerative brain diseases.

28 Mar 2018

Study provides insights into how male germ cells avoid genome instability

A group of researchers at Osaka University reported the function of GTSF1 in male germ cells. The study, which can be read in EMBO Reports, shows that GTSF1 is an essential factor for secondary piRNA biogenesis by regulating piRNA-mediated cleavage of target RNA.

28 Mar 2018

Researchers reveal role of extracellular protein in tumor growth and sustenance

Researchers at Okayama University describe in the journal Scientific Reports the role of an extracellular protein, versican, in regulating tumor growth and providing a newly formed network of blood vessels to further nourish the tumor.

28 Mar 2018

EPFL researchers uncover how the circadian clock regulates 3D chromatin structure

EPFL biologists and geneticists have uncovered how the circadian clock orchestrates the 24-hour cycle of gene expression by regulating the structure of chromatin, the tightly wound DNA-protein complex of the cell. The work is published in Genes & Development.

28 Mar 2018

FDA-approved inhibitors could be repurposed to target ARID1A-mutant ovarian cancers

Wistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for the treatment of diseases such as leukemia, as a new therapeutic option for ovarian cancer with mutations in the ARID1A gene.

27 Mar 2018

Previously unknown feature of human anatomy identified

Researchers have identified a previously unknown feature of human anatomy with implications for the function of all organs, most tissues and the mechanisms of most major diseases.

27 Mar 2018

Screening strategies could reduce multiple myeloma prevalence, mortality

Multiple myeloma is a rare incurable disease that is diagnosed in more than 30,000 people each year in the United States.

27 Mar 2018

Johns Hopkins researchers make great strides in understanding biology behind pulmonary hypertension

Working with cells that line the innermost layer of the blood vessels, Johns Hopkins investigators say they have made a leap forward in understanding the underlying biology behind pulmonary hypertension, a dangerous type of high blood pressure in lungs that ultimately leads to right heart failure and death.

27 Mar 2018

Combination therapy effectively induces tumor cell death and reduces spread of breast cancer

Each day, normal human cell tissues express a protein known as p53 that wages war against potential malignancies. However, between 30 and 40 percent of human breast cancers express a defective (mutant) form of p53 that helps cancer cells proliferate and grow.

27 Mar 2018

MSU scientists test promising drug to prevent cancer in high-risk patients

Michigan State University scientists are testing a promising drug that may stop a gene associated with obesity from triggering breast and lung cancer, as well as prevent these cancers from growing.

27 Mar 2018

Antibody sweeps away Alzheimer's plaques in mice

Years before people start showing characteristic symptoms of Alzheimer's disease, sticky plaques begin forming in their brains, damaging nearby cells. For decades, doctors have sought ways to clear out these plaques as a way to prevent or treat the disease.

27 Mar 2018

Protein C News and Research

UTSW study reveals mechanisms underlying development of Sonic Hedgehog medulloblastoma

Study identifies potential genetic link in sudden infant death syndrome

Seven ways to eat foods that have positive impact on budget and health

High levels of humanin protein found in placenta of women who delivered low-birthweight babies

Research pinpoints potential weak link in bacterial wall-building protein

Phase I clinical trial of HIV vaccines to begin in the U.S.

Study uncovers more complex, elaborate role for the body’s macromolecular complexes

New test detects Zika antibodies with high specificity

Biophysical mechanism involving spaghetti-like proteins helps cells avoid 'data breaches'

Simple bedside test may help doctors diagnose certain degenerative brain diseases

Study provides insights into how male germ cells avoid genome instability

Researchers reveal role of extracellular protein in tumor growth and sustenance

EPFL researchers uncover how the circadian clock regulates 3D chromatin structure

FDA-approved inhibitors could be repurposed to target ARID1A-mutant ovarian cancers

Previously unknown feature of human anatomy identified

Screening strategies could reduce multiple myeloma prevalence, mortality

Johns Hopkins researchers make great strides in understanding biology behind pulmonary hypertension

Combination therapy effectively induces tumor cell death and reduces spread of breast cancer

MSU scientists test promising drug to prevent cancer in high-risk patients

Antibody sweeps away Alzheimer's plaques in mice

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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