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Cardiologists question FDA recommendations on genetic testing before taking Plavix

Which antiplatelet medication is best after a coronary stent? The costly and potential life-or-death question lingers after most of the 600,000 angioplasties performed every year in the United States. The answer may lie in your genes, but professional cardiovascular societies and many working cardiologists question the U.S. Food and Drug Administration's recent recommendation that patients undergo genetic testing before taking Plavix (clopidogrel bisulfate).

14 Nov 2013

Research findings call for a rethinking of cancer genetics

Johns Hopkins researchers report that the deletion of any single gene in yeast cells puts pressure on the organism’s genome to compensate, leading to a mutation in another gene. Their discovery, which is likely applicable to human genetics because of the way DNA is conserved across species, could have significant consequences for the way genetic analysis is done in cancer and other areas of research, they say.

14 Nov 2013

Will Healthcare.gov troubles slow Medicaid expansion too?

Medicaid sign-ups, part of the health law working the way many officials thought it should, could also be hurt by technological malfunctions. But one state is finding the opposite to be true. In the meantime, states consider new Medicaid expansions or report on how many new Medicaid enrollees are signing up.

14 Nov 2013

Mount Sinai researchers successfully test SUMO-1 gene therapy to reverse heart failure

Researchers at the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai have successfully tested a powerful gene therapy, delivered directly into the heart, to reverse heart failure in large animal models.

14 Nov 2013

New finding challenges current models about how the brain processes visual information

University of Arizona doctoral degree candidate Jay Sanguinetti has authored a new study, published online in the journal Psychological Science, that indicates that the brain processes and understands visusal input that we may never consciously perceive.

14 Nov 2013

Study shows that geranylgeraniol suppresses viability of human DU145 prostate carcinoma cells

Researchers at Texas Woman's University have shown that a diterpene geranylgeraniol found in linseed oil, Cedrela toona wood oil, sucupira branca fruit oil and more recently, annatto seed oil, suppressed the viability of human DU145 prostate carcinoma cells via cell cycle arrest at the G1 phase and the initiation of apoptosis.

14 Nov 2013

Study identifies patterns of brain activity associated with eating disorders

A growing body of evidence shows the impact of diet on brain function, and identifies patterns of brain activity associated with eating disorders such as binge eating and purging. The findings were presented at Neuroscience 2013, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health.

14 Nov 2013

Imbruvica gets FDA approval for treatment of mantle cell lymphoma

The U.S. Food and Drug Administration today approved Imbruvica (ibrutinib) to treat patients with mantle cell lymphoma, a rare and aggressive type of blood cancer.

13 Nov 2013

Analysis of carbendazim in orange juice and wine

Bruker has released an application note on the evaluation of matrix effects on the analysis of carbendazim in orange juice and wine using the EVOQ Elite liquid chromatography mass spectrometer (LC-MS/MS). Carbendazim is a fungicide and a known endocrine with potentially harmful effects on human health.

From Bruker 13 Nov 2013

Derma Sciences third quarter 2013 net sales increase 12% to $22.1 million

Derma Sciences, Inc., a medical device and pharmaceutical company focused on advanced wound care, today reported financial and operating results for the three and nine months ended September 30, 2013.

13 Nov 2013

Cinderella effect not an inevitable reflex of stepparents, says scientist

Contrary to common belief, parents do not generally treat their stepchildren less favourably than their own. Until now, many researchers believed in the so-called "Cinderella effect." It states that it is biologically inevitable that parents care less for stepchildren because they do not spread their genes.

13 Nov 2013

Medicaid enrollment is 'early success story,' but website's problems are still causing sign-up difficulties

The Associated Press reports on the larger enrollment in states that are expanding their Medicaid programs. However, The New York Times points out that the snags on the marketplace websites may be holding up thousands of others who will be eligible for the state-federal program for low-income people.

13 Nov 2013

Studies suggest novel therapies for nicotine, heroin and gambling addiction

Studies released today suggest promising new treatments for nicotine and heroin addiction, and further our understanding of pathological gambling and heroin abuse in those suffering chronic pain.

12 Nov 2013

Obesity, bipolarity may have common mechanisms

The presence of obesity in patients with major depression could be a sign of underlying bipolarity, say researchers.

12 Nov 2013

Orexigen Therapeutics reports net loss of $18.6 million in Q3 2013

Orexigen Therapeutics, Inc., a biopharmaceutical company focused on the treatment of obesity, today announced business and financial results for the third quarter ended September 30, 2013.

12 Nov 2013

FDA Advisory Committee votes in favor of Cochlear Nucleus Hybrid L24 Implant System

Cochlear Limited, the global leader in implantable hearing solutions, announced today that an advisory committee to the US Food and Drug Administration voted favorably on the Cochlear Nucleus Hybrid L24 Implant System.

12 Nov 2013

ED visits associated with OTC pediatric cough cold medicines in children decline

A new study, "Cough and Cold Medication Adverse Events After Market Withdrawal and Labeling Revision," shows that emergency department visits associated with over-the-counter pediatric cough cold medicines in children age 3 and younger have declined following voluntary industry labeling initiatives specifically designed to improve safe use in this age.

12 Nov 2013

BioGaia plans to invest in first phase of project aimed at developing drug for NEC

The board of BioGaia has decided to invest in the first phase of a long-term project aimed at developing a drug with rigorous hygiene, analysis and documentation requirements, to treat the highly fatal disease Necrotising Enterocolitis, which affects premature infants.

12 Nov 2013

Shield Therapeutics files IND application with FDA to initiate ST10 Phase 3 study

Shield Therapeutics, an independent specialty pharmaceutical company focused on the development of mineral-derived hospital pharmaceuticals, today announces that it has filed an investigational new drug application with the US Food and Drug Administration to initiate a Phase 3 pivotal study of ST10, its novel oral iron-replacement therapy, for the treatment of iron deficiency anaemia in pre-dialysis patients with chronic kidney disease.

12 Nov 2013

Helsinn grants exclusive commercialization rights to Chugai Pharma Marketing for anamorelin drug

Swiss-based Helsinn group has granted Chugai Pharma Marketing Ltd., a wholly-owned subsidiary of Chugai Pharmaceutical Co., Ltd., exclusive commercialization rights to their innovative ghrelin receptor agonist, anamorelin, for the three major European pharma markets.

12 Nov 2013

Food News and Research

Cardiologists question FDA recommendations on genetic testing before taking Plavix

Research findings call for a rethinking of cancer genetics

Will Healthcare.gov troubles slow Medicaid expansion too?

Mount Sinai researchers successfully test SUMO-1 gene therapy to reverse heart failure

New finding challenges current models about how the brain processes visual information

Study shows that geranylgeraniol suppresses viability of human DU145 prostate carcinoma cells

Study identifies patterns of brain activity associated with eating disorders

Imbruvica gets FDA approval for treatment of mantle cell lymphoma

Analysis of carbendazim in orange juice and wine

Derma Sciences third quarter 2013 net sales increase 12% to $22.1 million

Cinderella effect not an inevitable reflex of stepparents, says scientist

Medicaid enrollment is 'early success story,' but website's problems are still causing sign-up difficulties

Studies suggest novel therapies for nicotine, heroin and gambling addiction

Obesity, bipolarity may have common mechanisms

Orexigen Therapeutics reports net loss of $18.6 million in Q3 2013

FDA Advisory Committee votes in favor of Cochlear Nucleus Hybrid L24 Implant System

ED visits associated with OTC pediatric cough cold medicines in children decline

BioGaia plans to invest in first phase of project aimed at developing drug for NEC

Shield Therapeutics files IND application with FDA to initiate ST10 Phase 3 study

Helsinn grants exclusive commercialization rights to Chugai Pharma Marketing for anamorelin drug

The future is bioengineered: Synthetic biology and global sustainability eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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