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USC researchers launch global project that aims to curb worldwide rise of diabetes

USC researchers have launched a massive scientific effort to construct a detailed, virtual 3-D model of the pancreatic beta cell and its components -- a global project that aims to one day curb the worldwide rise of diabetes.

26 Mar 2018

Scientists discover new family of promising silver-based anti-cancer drugs

A new family of very promising silver-based anti-cancer drugs has been discovered by researchers in South Africa. The most promising silver thiocyanate phosphine complex among these, called UJ3 for short, has been successfully tested in rats and in human cancer cells in the laboratory.

26 Mar 2018

Daily regimen of ibuprofen can ward off Alzheimer's disease, say neuroscientists

A Vancouver-based research team led by Canada's most cited neuroscientist, Dr. Patrick McGeer, has successfully carried out studies suggesting that, if started early enough, a daily regimen of the non-prescription NSAID (nonsteroidal anti-inflammatory drug) ibuprofen can prevent the onset of Alzheimer's disease.

26 Mar 2018

Researchers probe RNA epigenetics and chromatin structures to predict drug resistance in leukemia

Drug resistance is a major obstacle to effective treatment for patients with cancer and leukemia. Epigenetic modifying drugs have been proven effective for some patients with hematologic malignancies, such as myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML).

23 Mar 2018

Researchers characterize S. aureus gene involved in virulence and antibiotic resistance

An Institut Pasteur-CNRS research team has characterized a Staphylococcus aureus gene involved in virulence, biofilm formation and resistance to certain antibiotics.

23 Mar 2018

Genetic mutation that may protect people from malaria found to be more common

A genetic mutation that may protect people from malaria, but was thought to be rare, is surprisingly common, suggest the findings of a new study led by scientists at The Scripps Research Institute.

23 Mar 2018

Mutations found in bassoon gene may help explain cause of rare brain disorder

Newly discovered gene mutations may help explain the cause of a disease that drastically impairs walking and thinking.

23 Mar 2018

Researchers uncover cause of rare childhood neurodegenerative disease

Neurology researchers investigating a rare but devastating neurological regression in infants have discovered the cause: gene mutations that severely disrupt crucial functions in mitochondria, the energy-producing structures within cells.

23 Mar 2018

What gives the curl to curly hair? Sheep wool provides clues

There has been no research that explains what gives the curl to curly hair. To understand this, the researchers looked at the microscopic structure of the hair and measure the individual hair cells in the curly hair that could explain the curls. However human hair was found to be too thick for these experiments. So as a next step they looked at naturally curly hair or wool from six Merino sheep from New Zealand. This provided them with the answers they were looking for. The study results were published this week in the latest issue of the Journal of Experimental Biology.

23 Mar 2018

New study identifies key cellular mechanisms behind vascular aging in mice

We are as old as our arteries, the adage goes, so could reversing the aging of blood vessels hold the key to restoring youthful vitality? The answer appears to be yes, at least in mice, according to a new study led by investigators at Harvard Medical School.

22 Mar 2018

New findings could have revolutionary impact on quality of life of older people

Researchers from UNSW and Harvard Medical School have discovered that replacing two naturally occurring molecules in the body could reverse symptoms of aging, potentially influencing how the body responds to and performs exercise.

22 Mar 2018

Researchers make key discovery about cellular pathway linked to myriad of diseases

Researchers from the University of Dundee and the Francis Crick Institute have made a significant discovery about a cellular pathway associated with developmental defects and a myriad of diseases ranging from alopecia to colorectal cancer.

22 Mar 2018

Gut microbiome may promote pancreatic cancer by inducing immune suppression

Bacterial load was significantly higher in pancreatic tumor samples from patients with pancreatic ductal adenocarcinoma compared with pancreatic tissue from normal individuals, and in studies using mice, eliminating certain "bad" bacteria slowed the growth of pancreatic cancer, reversed immune suppression, and upregulated the immune checkpoint protein PD1.

22 Mar 2018

Weight-loss surgery reduces risk for severe chronic kidney disease and kidney failure

Patients that underwent weight-loss surgery ran a significantly lower risk of developing severe chronic kidney disease and kidney failure, when compared to conventionally treated patients, according to a study published in International Journal of Obesity.

22 Mar 2018

Researchers explain link between 2 key Alzheimer's proteins

It's a paradox of Alzheimer's disease: Plaques of the sticky protein amyloid beta are the most characteristic sign in the brain of the deadly neurodegenerative disease. However, many older people have such plaques in their brains but do not have dementia.

21 Mar 2018

Neuroscientists move closer to developing tools for deciphering brain function

A team of University of Missouri neuroscientists are inching closer to developing the tools needed to decipher the brain.

21 Mar 2018

Targeting aberrantly active telomerase to treat therapy-resistant melanoma

A study conducted at The Wistar Institute in collaboration with The University of Texas Southwestern Medical Center has demonstrated the efficacy of targeting aberrantly active telomerase to treat therapy-resistant melanoma.

21 Mar 2018

Discovery of new ALS gene points to cytoskeleton as potential target for drug development

An international team of researchers led by John Landers, PhD, at UMass Medical School, and Bryan Traynor, MD, PhD, at the National Institute on Aging at the National Institutes of Health, has identified KIF5A as a new gene associated with the development of amyotrophic lateral sclerosis.

21 Mar 2018

Protein profiling reveals new prostate cancer mechanisms

A study by the University of Tampere in Finland used protein profiling to find new prostate cancer mechanisms that are not shown by aberrations at the genomic level. Several new potential biomarkers of prostate cancer were also found.

21 Mar 2018

New DOD grant to support testing of promising therapy for triple-negative breast cancer

A unique cell surface protein found on triple-negative type breast cancer cells called JAG1 is a promising new therapeutic target for this hard-to-treat and highly metastatic type of breast cancer, according to researchers at the University of Illinois at Chicago.

21 Mar 2018

Protein C News and Research

USC researchers launch global project that aims to curb worldwide rise of diabetes

Scientists discover new family of promising silver-based anti-cancer drugs

Daily regimen of ibuprofen can ward off Alzheimer's disease, say neuroscientists

Researchers probe RNA epigenetics and chromatin structures to predict drug resistance in leukemia

Researchers characterize S. aureus gene involved in virulence and antibiotic resistance

Genetic mutation that may protect people from malaria found to be more common

Mutations found in bassoon gene may help explain cause of rare brain disorder

Researchers uncover cause of rare childhood neurodegenerative disease

What gives the curl to curly hair? Sheep wool provides clues

New study identifies key cellular mechanisms behind vascular aging in mice

New findings could have revolutionary impact on quality of life of older people

Researchers make key discovery about cellular pathway linked to myriad of diseases

Gut microbiome may promote pancreatic cancer by inducing immune suppression

Weight-loss surgery reduces risk for severe chronic kidney disease and kidney failure

Researchers explain link between 2 key Alzheimer's proteins

Neuroscientists move closer to developing tools for deciphering brain function

Targeting aberrantly active telomerase to treat therapy-resistant melanoma

Discovery of new ALS gene points to cytoskeleton as potential target for drug development

Protein profiling reveals new prostate cancer mechanisms

New DOD grant to support testing of promising therapy for triple-negative breast cancer

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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