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Discovery of two gene variants associated with increased risk for early heart attack

Scientists at University of California - San Francisco (UCSF), Celera Genomics and The Cleveland Clinic have discovered two gene variants associated with a significantly increased risk for early heart attack, or myocardial infarction (MI).

12 May 2006

Study holds promise for malarial susceptibility test

Cell and animal studies conducted jointly by scientists at Johns Hopkins, Yale and other institutions have uncovered at least one important contributor to the severe anemia that kills almost half of the 2 million people worldwide who die each year of malaria.

12 May 2006

Study sheds light on cancer susceptibility and disease involving bone-marrow failure

Defective protein production can occur in cells even when the genes controlling those proteins are normal, according to a new study to be published May 12 in Science.

12 May 2006

The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis

An imbalance in the lipid content of the liver appears to trigger the downward spiral that leads some with fatty liver disease to advance to full-blown liver failure, according to a new study in the May Cell Metabolism.

11 May 2006

Ghrelin involved in development of diabetes

Ghrelin, a hormone long considered a key player in obesity, may instead take a major role in maintaining the balance between insulin and glucose and the development of diabetes, said Baylor College of Medicine researchers in a report in the current issue of the journal Cell Metabolism.

11 May 2006

Researchers link novel mutated gene to mental retardation and imbalance syndrome

Researchers at the University of California, San Diego School of Medicine have identified a genetic cause for a form of pediatric brain malformation involving the cerebellum.

11 May 2006

Gene amplification could guide treatment for high-risk breast cancer

A new study shows that breast cancer patients with an "amplification," or greater number of copies, of the TOP2A gene are 45% more likely than women who do not have this amplification to benefit from a longer course of anthracycline-based adjuvant chemotherapy.

11 May 2006

Healthy habits and appropriate treatments help prevent stroke

Stroke is the third leading cause of death and a major source of disability in the United States. Every year about 700,000 people in the United States suffer a stroke, resulting in nearly 158,000 deaths.

10 May 2006

Neurons can produce Alzheimer's-linked apolipoprotein E

A question long debated among Alzheimer's disease researchers has been definitively answered by scientists at the Gladstone Institute of Neurological Disease in San Francisco.

10 May 2006

New phase-contrast microscopy developed at PSI enhances X-ray images

Imaging techniques are increasingly at the forefront of progress in science and technology.

10 May 2006

Unique protein expression could serve as a screening test for head and neck cancers

The blood of patients with head and neck cancer appears to have unique patterns of protein expression that one day could serve as a screening test for the highly aggressive cancer that is often diagnosed too late, researchers say.

10 May 2006

Promising chemo, therapeutic viruses, cutting-edge surgery debut at M. D. Anderson Cancer Center

Brain tumor specialists at The University of Texas M. D. Anderson Cancer Center are poised on the brink of a new era.

10 May 2006

Scientists unlock more secrets of HIV and SARS

UK scientists have cracked one of the key biological processes used by viruses such as HIV and SARS when they replicate according to a paper published in the journal Nature tomorrow (11 May). Viruses are able to interfere with the host cell processes that our bodies use to replicate cells, and protein synthesis is often one of their targets.

10 May 2006

Stem cell 'fusion' occurs in tumors

An Oregon Health & Science University study is adding credence to an increasingly popular theory that fusion is what bonds stem cells with bone marrow cells to regenerate organ tissue.

10 May 2006

Study reveals structure of E. coli multidrug transporter protein

This new study could potentially help researchers find new ways to avoid the problem of multidrug resistance and enhance the potency of existing drug compounds.

9 May 2006

"Junk" RNA regulates important cellular processes

It has been known for a long time that much of a cell’s RNA stems from DNA regions called intergenic spacers (IGS) that lie between two genes and do not code for proteins.

9 May 2006

New insight into the way an embryonic retina cell develops

The discovery provides a new vantage point for understanding how a healthy visual system develops. It also raises the possibility of re-directing the production of cell types as needed to stave off eye disease.

9 May 2006

Renewed interest in studying influenza A viruses

The emergence of the avian influenza virus H5N1 that is currently devastating chicken flocks in many countries and threatening to unleash a worldwide epidemic among humans has triggered a renewed interest among scientists in studying influenza A viruses, according to investigators at St. Jude Children's Research Hospital.

9 May 2006

Advancing nanoparticle-based imaging and therapy of brain cancer

Brain cancer is one of the most difficult malignancies to detect and treat, in large part because of the difficulty in getting imaging and therapeutic agents past the so-called blood-brain barrier and into the brain.

9 May 2006

Scientists assemble a complete viral coat around a gold nanoparticle

Using a short piece of DNA as a template, a team of investigators at North Carolina State University has assembled a complete viral coat around a gold nanoparticle.

9 May 2006