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Research establishes use of chimeric cells as potential therapy for Duchenne muscular dystrophy

Cells made by fusing a normal human muscle cell with a muscle cell from a person with Duchenne muscular dystrophy --a rare but fatal form of muscular dystrophy -- were able to significantly improve muscle function when implanted into the muscles of a mouse model of the disease.

16 Mar 2018

Research identifies barriers that may prevent Black Americans from screening for CKD

The incidence of kidney failure is 3 times higher in Black Americans than in whites, and the prevalence of chronic kidney disease continues to rise among Black Americans while it has stabilized in other racial groups.

16 Mar 2018

UCLA-developed nanospears could make gene therapies safer, faster and more cost-effective

UCLA scientists have developed a new method that utilizes microscopic splinter-like structures called "nanospears" for the targeted delivery of biomolecules such as genes straight to patient cells. These magnetically guided nanostructures could enable gene therapies that are safer, faster and more cost-effective.

15 Mar 2018

TSRI scientists discover new pathway to promote mitochondrial function during stress

Scientists at The Scripps Research Institute have discovered a new pathway in cells that promotes mitochondrial function during times of stress, a response that can guard against disease as we age.

15 Mar 2018

Transplanting enhanced interneurons restores brain rhythms in mouse model of Alzheimer’s

Like a great orchestra, your brain relies on the perfect coordination of many elements to function properly. And if one of those elements is out of sync, it affects the entire ensemble. In Alzheimer's disease, for instance, damage to specific neurons can alter brainwave rhythms and cause a loss of cognitive functions.

15 Mar 2018

New blood test promises to eliminate guesswork in heart attack diagnosis

A new blood test developed by a University of Alberta physician promises to eliminate the guesswork clinicians face with an apparent heart attack.

15 Mar 2018

Researchers uncover link between Parkinson’s disease mutations and plaque formation in the brain

Working with lab-grown human brain cells, Johns Hopkins researchers report they have uncovered a much sought-after connection between one of the most common genetic mutations in Parkinson's disease and the formation of fatty plaques in the brain thought to contribute to the destruction of motor neurons that characterize the disease.

15 Mar 2018

Researchers unravel how gingival mesenchymal stem cells accelerate wound healing

Ever notice how a cut inside the mouth heals much faster than a cut to the skin? Gum tissue repairs itself roughly twice as fast as skin and with reduced scar formation. One reason might be because of the characteristics of gingival mesenchymal stem cells, or GMSCs, which can give rise to a variety of cell types.

15 Mar 2018

University of Akron professor receives NSF grant for research that supports anti-cancer therapeutics

Dr. Adam W. Smith, assistant professor in the Department of Chemistry, has won a CAREER award from the National Science Foundation. The title of the award is "Lipid Regulation of Receptor Tyrosine Kinases" and provides $650,000 of funding for research.

15 Mar 2018

Researcher working to develop improved endoscopic probe for colonoscopies

Tim Muldoon, assistant professor of biomedical engineering, has received a $500,000 Faculty Early Career Development Program award from the National Science Foundation to continue his work on an endoscopic probe that can be used in colonoscopies.

14 Mar 2018

Scientists explore how to protect obese, premenopausal women from cardiovascular risk

Obese, premenopausal women can lose the innate protection from cardiovascular disease that their youth and estrogen are believed to afford, and scientists want to know how.

14 Mar 2018

Researchers achieve 80% reduction in liver metastasis by restricting growth of blood vessels

The International Journal of Cancer has just published the results of an experimental therapy tested on mice. The research, led by the Signaling Lab research group of the UPV/EHU's Faculty of Medicine and Pharmacy and the Department of Pharmacology, Pharmacy and Pharmaceutical Technology of the University of Santiago de Compostela, achieved an 80% reduction in liver metastasis brought about by colon cancer.

14 Mar 2018

Researchers identify novel gene involved in familial breast cancer

An international research consortium led by Dr Jordi Surrallés, director of the Genetics Service at the Hospital de Sant Pau and professor of Genetics at the UAB, and by Dr Miquel Àngel Pujana, director of the ProCURE Research Programme of the Catalan Institute of Oncology, has identified a novel gene involved in this type of cancer, known as EDC4.

14 Mar 2018

Tumor's 'microenvironment' plays key role in altering therapeutic response of breast cancer

Cancer is typically thought of as a tumor that needs to be removed or an area that needs to be treated with radiation or chemotherapy. As a physicist and cancer researcher, Joe Gray, Ph.D., thinks differently.

14 Mar 2018

Study highlights divergent molecular mechanisms contributing to depression in men and women

Men and women with major depressive disorder have opposite changes in the expression of the same genes, according to a new postmortem brain study by researchers at the University of Pittsburgh and Centre for Addiction and Mental Health, Toronto, Canada.

14 Mar 2018

New guidelines intend to provide template for optimal, most up-to-date DMD care

Diagnostic and treatment advances are helping patients with Duchenne muscular dystrophy - one of nine major types of muscular dystrophy that affects males - live into their 30s and beyond, raising challenges in such areas as education, vocation, levels of independence, personal relationships, emotional health, and intimacy.

13 Mar 2018

Study: Soy-fed infants have differences in reproductive system tissues

Infants who consumed soy-based formula as newborns had differences in some reproductive-system cells and tissues, compared to those who used cow-milk formula or were breastfed, according to a new study.

13 Mar 2018

Extracellular vesicles may serve as drug delivery vehicles for cancer treatment

Creating enough nanovesicles to inexpensively serve as a drug delivery system may be as simple as putting the cells through a sieve, according to an international team of researchers who used mouse autologous -- their own -- immune cells to create large amounts of fillable nanovesicles to deliver drugs to tumors in mice.

13 Mar 2018

NIH-funded researchers use CRISPR to rapidly find new genetic suspects behind ALS, FTD

NIH-funded researchers at Stanford University used the gene editing tool CRISPR-Cas9 to rapidly identify genes in the human genome that might modify the severity of amyotrophic lateral sclerosis and frontotemporal dementia caused by mutations in a gene called C9orf72.

13 Mar 2018

Korean scientists track growth, migration of cells under hypoxic conditions using xCELLigence RTCA

Tracking the growth and migration of cells under hypoxic conditions in vitro can be challenging because measurements must be made in a manner that does not perturb the atmospheric composition of the closed system.

13 Mar 2018

Protein C News and Research

Research establishes use of chimeric cells as potential therapy for Duchenne muscular dystrophy

Research identifies barriers that may prevent Black Americans from screening for CKD

UCLA-developed nanospears could make gene therapies safer, faster and more cost-effective

TSRI scientists discover new pathway to promote mitochondrial function during stress

Transplanting enhanced interneurons restores brain rhythms in mouse model of Alzheimer’s

New blood test promises to eliminate guesswork in heart attack diagnosis

Researchers uncover link between Parkinson’s disease mutations and plaque formation in the brain

Researchers unravel how gingival mesenchymal stem cells accelerate wound healing

University of Akron professor receives NSF grant for research that supports anti-cancer therapeutics

Researcher working to develop improved endoscopic probe for colonoscopies

Scientists explore how to protect obese, premenopausal women from cardiovascular risk

Researchers achieve 80% reduction in liver metastasis by restricting growth of blood vessels

Researchers identify novel gene involved in familial breast cancer

Tumor's 'microenvironment' plays key role in altering therapeutic response of breast cancer

Study highlights divergent molecular mechanisms contributing to depression in men and women

New guidelines intend to provide template for optimal, most up-to-date DMD care

Study: Soy-fed infants have differences in reproductive system tissues

Extracellular vesicles may serve as drug delivery vehicles for cancer treatment

NIH-funded researchers use CRISPR to rapidly find new genetic suspects behind ALS, FTD

Korean scientists track growth, migration of cells under hypoxic conditions using xCELLigence RTCA

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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