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PCORI approves up to $50 million in funding for new projects to address COVID-19

The Patient-Centered Outcomes Research Institute (PCORI) Board of Governors today, building on its rapid response to the COVID-19 health crisis, approved allocating up to $50 million in additional funding for new projects in PCORI's COVID-19 funding opportunities, as well as enhancements to existing PCORI-funded studies.

23 Jun 2020

Heart failure poses the greatest risk of death for people with type 2 diabetes

Heart failure posed the greatest 5-year risk of death for people newly diagnosed with Type 2 diabetes than any other heart or kidney disease, according to new research published today in Circulation: Cardiovascular Quality and Outcomes, an American Heart Association journal.

23 Jun 2020

Pandemic forced insurers to pay for in-home treatments. Will they disappear?

After seven days as an inpatient for complications related to heart problems, Glenn Shanoski was initially hesitant when doctors suggested in early April that he could cut his hospital stay short and recover at home — with high-tech 24-hour monitoring and daily visits from medical teams.

23 Jun 2020

Defective maintenance puts intestinal health in danger

In order to keep the intestinal mucosa and the entire organism healthy, intestinal epithelial cells have developed various protective functions involving a number of maintenance mechanisms that protect cells from stress.

23 Jun 2020

The hidden deaths of the COVID pandemic

Sara Wittner had seemingly gotten her life back under control. After a December relapse in her battle with drug addiction, the 32-year-old completed a 30-day detox program and started taking a monthly injection to block her cravings for opioids.

23 Jun 2020

COVID-19 opens new opportunities for CGM systems in the diabetic care market

Following reports that people with diabetes are among the most vulnerable to serious complications caused by COVID-19, the demand of continuous glucose monitors (CGM) is rising. According to GlobalData, the global CGM market was valued at $3.3bn in 2019 prior to the pandemic.

23 Jun 2020

Researchers discover key protein that can reduce damage caused by heart attack

In a heart attack, a series of biochemical processes leave the heart damaged, much like a car after an accident.

23 Jun 2020

Research shows females use anti-inflammatory T cells to maintain their blood pressure

In the face of a multipronged front to drive blood pressure up, including a high-salt diet, females are better able to keep their pressure down by increasing levels of a T cell that selectively dials back inflammation, scientists say.

23 Jun 2020

Colombian corona hounds: SAR-CoV-2 detection by dogs

A new Colombian study published on the preprint server bioRxiv in June 2020 describes the use of trained dogs to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected humans by scent alone. This would allow uninfected people to work together safely, rescuing the economy without driving up medical costs.

23 Jun 2020

Characterizing SARS-CoV-2 convalescent plasma

A new study published on the preprint server bioRxiv in June 2020 uses serologic correlates to assess the efficacy of convalescent plasma. This will also help to classify donor plasma as more or less potent at neutralizing the virus.

23 Jun 2020

Prior infection provides protection against SARS-CoV-2 virus in hamsters

In an animal model for COVID-19 that shares important features of human disease, scientists at the University of Wisconsin–Madison, the University of Tokyo and the Icahn School of Medicine at Mount Sinai show that prior infection with the SARS-CoV-2 virus provides protection against reinfection, and treatment with convalescent serum limits virus replication in their lungs.

22 Jun 2020

UTHealth tests arthritis drug's effect on COVID-19-induced cytokine storm

A drug is being studied for its effectiveness in treating a type of severe immune overreaction seen in patients with COVID-19-induced pneumonia by researchers at The University of Texas Health Science Center at Houston.

22 Jun 2020

HCV-positive organs can be safely used for transplantation, study shows

Patients who received a transplanted liver infected with hepatitis C and were later treated for the infection performed as well in recovery as transplant patients who received an organ free of infection, according to study from the University of Cincinnati College of Medicine and UC Health recently published in the journal Liver Transplantation.

22 Jun 2020

New method for producing tsetse fly attractants using biotechnology

The tsetse fly occurs in large regions of sub-Saharan Africa. The flies feed on human and animal blood, transmitting trypanosoma in the process - small, single-cell organisms that use the flies as intermediate host and cause a dangerous inflammation of the lymph and nervous system in both animals and humans.

22 Jun 2020

Researchers identify mouse model that mimics HFpEF syndrome in humans

A receptor that plays an essential role in safely clearing chronic unresolved cardiac inflammation may offer new targets for treating an increasing type of heart failure associated with age-related obesity, suggests a preclinical study led by researchers at the University of South Florida Health Heart Institute, Morsani College of Medicine.

22 Jun 2020

Novel vaccine platform against COVID-19 based on engineered human mesenchymal stem cells

In a recent groundbreaking bioRxiv paper, Chinese researchers describe a novel approach towards coronavirus disease (COVID-19) vaccine design based on engineered human mesenchymal stem cells, with favorable and promising antibody response.

22 Jun 2020

Reassuring news on the Oxford vaccine (AZD1222) against SARS-CoV-2

A new paper from the UK vaccine research group, currently available on the bioRxiv preprint server, reveals that a single dose of ChAdOx1 nCoV-19 (AZD1222) can induce antigen-specific antibody and T cells responses against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and a booster shot additionally enhances antibody production with an increase in neutralizing titers – particularly in pigs.

22 Jun 2020