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Genzyme begins gene transfer trial for peripheral arterial disease

Genzyme Corporation announced today that the first patient has been treated in a new phase 2 clinical trial examining the safety and effectiveness of locally delivered gene transfer for patients with peripheral arterial disease.

24 Feb 2005

Should screening for sleep apnea be required for all men?

According to a new study, men in their 20s need to be screened the most. That's because men aged 20 to 29 with severe sleep apnea have 10 times the risk of dying from heart related ailments than their non sleep apnea peers in the general population, and a much higher risk than older men with sleep apnea.

24 Feb 2005

Trial results on the use of recombinant activated factor VII in acute intracerebral haemorrhage

The New England Journal of Medicine (NEJM) today reports positive results from the recently completed clinical trial of recombinant activated factor VII (NovoSeven/rFVIIa) in intracerebral haemorrhage (ICH).

24 Feb 2005

Counseling smokers to quit reduced their chances of dying

Giving up smoking after a heart attack has been clearly associated with improvements in long-term patient survival, but how soon after myocardial infarction does smoking cessation begin to have positive effects?

24 Feb 2005

FDA approves Atacand (candesartan cilexetil) for the treatment of heart failure

AstraZeneca today announced that the US Food and Drug Administration (FDA) has approved its angiotensin receptor blocker (ARB) Atacand (candesartan cilexetil) Tablets for the treatment of heart failure (NYHA class II-IV and ejection fraction less than or equal to 40%) to reduce the risk of death from cardiovascular causes and reduce hospitalizations for heart failure.

23 Feb 2005

Antimicrobials improperly used about 50% of the time

Antimicrobial medications intended to prevent surgical site infections are appropriately administered to patients (within one hour before incision) only 55.7 percent of the time, according to a study published in the February issue of Archives of Surgery.

21 Feb 2005

New clues to amyloidoses

Familial amyloid polyneuropathy (FAP), a hereditary disease characterised by abnormal deposits of insoluble protein in the organs, results from a mutation in a single gene (the transthyretin or TTR gene). Nevertheless, disease incidence and age of onset can vary significantly between patients what have always puzzled scientists.

21 Feb 2005

Mathematical model helps women determine frequency of mammograms

Researchers at Dana-Farber Cancer Institute in Boston have devised a mathematical tool that predicts how the frequency of mammograms affects the number of lives saved by detecting breast cancers at an earlier stage.

20 Feb 2005

Biochemical marker aids prognosis in liver transplant patients

A new study on whether the model used to identify patients most in need of a liver transplant can be improved upon found that measuring serum sodium in potential transplant patients helps to better predict those with a poor prognosis.

20 Feb 2005

Massachusetts support of stem cell research

The Massachusetts Medical Society, the statewide association of physicians with some 18,000 members, has offered testimony before the Joint Committee on Economic Development and Emerging Technologies in support of Senate Bill 25, An Act Promoting Stem Cell Research.

17 Feb 2005

Deaths from mesothelioma will peak within ten years in the UK

Deaths from mesothelioma, an asbestos-related lung cancer, will peak within ten years in the UK and then fall to a much lower level, according to new figures published in this week's British Journal of Cancer.

17 Feb 2005

Nonsurgical microspheres an option for liver cancer patients

A study in February’s Journal of Vascular and Interventional Radiology found that patients undergoing liver cancer treatment with Theraspheres?, radioactive microspheres containing Yittrium-90, can tolerate a 150 Gy single dose or 268 Gy repeated dose without risk of radiation-induced liver disease.

17 Feb 2005

Ebola virus outbreaks linked to infected wild animal carcasses

All recent Ebola virus outbreaks in humans in forests between Gabon and the Republic of Congo were the result of handling infected wild animal carcasses, according to a study by the Wildlife Conservation Society (WCS) and its regional partners

14 Feb 2005

Older heart transplant recipients fare just as well as their younger counterparts

Policy makers who use age as a discriminating factor in determining eligibility for heart transplant surgery may want to reconsider their rules in the light of new research at the University of Alberta.

14 Feb 2005

Alcohol drinkers three times as lkely to die from injury

People who regularly drink alcohol are three times as likely to die from injury as are non-drinkers and former drinkers of alcohol, according to new research from the Center for Injury Research and Policy at the Johns Hopkins Bloomberg School of Public Health.

10 Feb 2005

Expanded HIV screening can increase patient life span

Expanded HIV screening can increase patient life span, prevent the spread of the disease, and is cost effective, researchers at Yale, Harvard and the Massachusetts General Hospital report in the February 10 issue of the New England Journal of Medicine (NEJM).

10 Feb 2005

Bush Administration opens the door to the elimination of critical health services for the most vulnerable women, infants and children

"The budget proposal released by the Administration this morning opens the door to the elimination of critical health services for the most vulnerable women, infants and children. The March of Dimes strongly opposes any attempt to narrow Medicaid benefits for these at risk groups.

7 Feb 2005

Racial differences may play a significant role in determining a patient's response to asthma medications

A new study in the February issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians (ACCP), shows that asthmatic and nonasthmatic African-Americans required higher doses of glucocorticoids to suppress lymphocytes, which play an important role in airway inflammation.

7 Feb 2005

Risks of obesity in children with kidney transplants

Obese children who get kidney transplants tend to be younger, shorter and on dialysis longer than their leaner peers, according to a study in the February issue of the journal Pediatrics.

7 Feb 2005

Varicella vaccine is almost 90 percent effective against chickenpox

The varicella vaccine is almost 90 percent effective against chickenpox, but its impact on herpes zoster (shingles) is unknown and needs wider surveillance, Yale School of Medicine researchers write in today's New England Journal of Medicine (NEJM) perspective section.

7 Feb 2005