Antimicrobial Drug News and Research

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Antimicrobials are substance that kills microorganisms such as bacteria or mold, or stops them from growing and causing disease.

LL37 peptide provides a new potential target for autoimmune disease

A human peptide that acts as a natural antibiotic against invading microbes can also bind to the body's own DNA and trigger an immune response in the absence of an infection, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in an early online publication in Nature.

17 Sep 2007

Organisms found on contact lenses provide clues to corneal eye infections

Cultures of contact lenses may sometimes identify the organisms involved in cases of corneal eye infection, according to a report in the September issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

11 Sep 2007

Bad news for disease-causing bacteria!

Scientists have what could be some very bad news for disease-causing bacteria. All three major classes of antibiotics that kill infectious bacteria do so in part by ramping up the production of harmful free radicals, researchers report in the September 7, 2007, issue of Cell, a publication of Cell Press.

10 Sep 2007

Quick microchip test for dangerous and drug resistant bacteria in clinical samples

Researchers at the Veterinary Laboratories Agency in Surrey have developed microchips capable of quickly and cheaply identifying dangerous and drug resistant bacteria in clinical samples, scientists announced (Wednesday 5 September 2007) at the Society for General Microbiology's 161st Meeting at the University of Edinburgh, UK, which runs from 3-6 September 2007.

5 Sep 2007

Ardea Biosciences completes phase 1 trials of HIV drug RDEA806

Ardea Biosciences, Inc. has announced that it has successfully completed Phase 1 single-ascending-dose, multiple-ascending-dose, food-effect, and drug-interaction studies of RDEA806, a novel HIV non-nucleoside reverse transcriptase inhibitor (NNRTI), in healthy volunteers.

5 Sep 2007

Irish study to look at how bacteria, Yersinia enterocolitica, enters the food chain

Monitoring of pig carcasses and pig meat in slaughterhouses, butchers' premises and retail outlets will be undertaken in Ireland over the next two years in an attempt to determine how a human disease causing bacteria, Yersinia enterocolitica, enters the food chain, scientists announced today (Tuesday 4 September 2007) at the Society for General Microbiology's 161st Meeting at the University of Edinburgh, UK, which runs from 3-6 September 2007.

4 Sep 2007

Carbon nanotubes to fight E. coli

Single-walled carbon nanotubes (SWCNTs) can kill bacteria like the common pathogen E. coli by severely damaging their cell walls, according to a recent report from Yale researchers in the American Chemical Society (ACS) journal Langmuir.

30 Aug 2007

Researchers discover nature uses a recurring molecular strategy to defend against infection

With infections increasingly resistant to even the most modern antibiotics, researchers at the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed) report in the September issue of Nature Reviews Microbiology on new clues they have uncovered in immune system molecules that defend against infection.

30 Aug 2007

Gamma globulin effective treatment for pinkeye

Gamma globulin, a type of antibody isolated from blood samples that used to be routinely given to health care workers and international travelers to protect them from infectious diseases, is a highly effective treatment for pinkeye with little apparent toxicity, according to a study by researchers at the University of Pittsburgh School of Medicine.

29 Aug 2007

Global public health security in the 21st century

More than at any previous time in history, global public health security depends on international cooperation and the willingness of all countries to act effectively in tackling new and emerging threats.

23 Aug 2007

Natural antimicrobial agents for food safety

Two items high on the list of public concerns are the need for greater food safety and a growing demand for natural or organic food products.

22 Aug 2007

Pigs key to understanding antibiotic resistant bacteria

NSW Department of Primary Industries (NSW DPI) Immunology & Molecular Diagnostic Research Unit Team Leader, Dr James Chin, says it is commonly believed that each time an antibiotic is used only pathogens or disease-causing bacteria will be killed.

1 Aug 2007

New treatment to combat bowel infection among the elderly

Scientists at the Alimentary Pharmabiotic Centre (APC), based in University College Cork (UCC) and Teagasc’s Moorepark Food Research Centre, are researching a new treatment to combat the increasing incidences of hospital acquired diarrhoea which has become a major problem in hospitals, nursing homes and facilities for the elderly.

1 Aug 2007

Latest MRSA bloodstream infections and Clostridium difficile figures

Latest figures for MRSA show there was a 6.4% fall in the number of cases of blood stream infection reported to the Health Protection Agency from January - March 2007.

26 Jul 2007

GPs antibiotic prescribing practices are still contributing to resistance

GPs are still prescribing antibiotics for up to 80% of cases of sore throat, otitis media, upper respiratory tract infections, and sinusitis, despite the fact that official guidance warns against this practice, according to an analysis of the world's largest primary care database of consultations and prescriptions, published this week in a supplement to the Journal of Antimicrobial Chemotherapy.

26 Jul 2007

Scientists invent novel low-viscosity gel for regenerating human tissue

University of Delaware scientists have invented a novel biomaterial with surprising antibacterial properties that can be injected as a low-viscosity gel into a wound where it rigidifies nearly on contact--opening the door to the possibility of delivering a targeted payload of cells and antibiotics to repair the damaged tissue.

19 Jul 2007

Natural polymer Chitin shows great healing properties

Chitin is a polymer very common in nature as part of animals' and plants' physical structures.

16 Jul 2007

FDA stops Chinese seafood importation

The Food and Drug Administration (FDA) today announced a broader import control of all farm-raised catfish, basa, shrimp, dace (related to carp), and eel from China.

29 Jun 2007

Stanford researchers get scoop on baby poop!

Researchers at the Stanford University School of Medicine are as interested in a baby's poop as doting parents are, and for good reason.

26 Jun 2007

Anacor finds novel mechanism for lead anti-fungal drug, AN2690

Anacor Pharmaceuticals, a privately held pharmaceutical company, has announced that the journal Science will publish results of research that details how AN2690, the company's lead clinical candidate, kills fungal cells by interfering with synthesis of a specific protein required for fungal growth.

23 Jun 2007