Immunohistochemistry News and Research

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Immunohistochemistry (IHC) is an imaging technique to visualize antigens in cells. Labeled antibodies bind to target antigens in the cell to image the distribution and localization of specific proteins of interest

Could COVID-19 infections trigger a relapse of mycosis fungoides or other cutaneous T-cell lymphomas?

Recently, authors highlighted the potential role of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in triggering the relapse of mycosis fungoides, a type of cutaneous T-cell lymphoma.

17 Oct 2022

New partnership creates an automated anatomic pathology slide-scanning solution

Sakura Finetek, a global leader in histopathology products and Evident Scientific, a wholly owned subsidiary of Olympus Corporation, and a global leader in microscopy and imaging solutions, today announced a collaboration to offer a full workflow solution for anatomic pathology slide preparation and high-resolution digital scanning in the Americas.

From Evident Corporation - Life Sciences 13 Oct 2022

Neonatal mice-based model established that allows for the transmission of clinical SARS-CoV-2 isolates

Researchers established a neonatal mice model that enabled SARS-CoV-2 transmission.

7 Oct 2022

Study links pancreatic cancer survival outcomes with arrangement of immune cells in tumors

Researchers from Johns Hopkins Medicine have discovered that the organization of different types of immune cells within pancreatic tumors is associated with how well patients with pancreatic cancer respond to treatment and how long they survive.

6 Oct 2022

Brazilian study reveals the effects of SARS-CoV-2 infection on the central nervous system

A Brazilian study published in the journal PNAS describes some of the effects infection by SARS-CoV-2 can have on the central nervous system.

30 Sep 2022

SARS-CoV-2 spike protein and messenger ribonucleic acid found to translocate into the nucleus

In a new study, researchers reported severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) spike (S) protein and S messenger ribonucleic acid (mRNA) nuclear co-translocation as a novel feature of SARS-CoV-2 pathogenesis.

30 Sep 2022

Virology of the human monkeypox virus

A new review to be posted in the Virus Research journal aims to provide an overview of the recent advances reported concerning hMPXV virology.

21 Sep 2022

Signal transduction via the EGFR pathway likely to be involved in lenvatinib resistance

The multitargeted tyrosine kinase inhibitor (MKI), lenvatinib, is widely used to treat advanced and metastatic thyroid cancer. However, the molecular mechanisms by which thyroid cancer cells become resistant to lenvatinib remain poorly understood. In this study, we demonstrated, for the first time, that activation of the epidermal growth factor receptor (EGFR)-mediated signaling pathway is involved in lenvatinib resistance in thyroid cancer cells.

14 Sep 2022

How does SARS-CoV-2 affect the male genitourinary system?

In a recent paper published in the American Journal of Clinical and Experimental Urology, researchers reviewed existing data on the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections on the male genitourinary (GU) tract.

7 Sep 2022

The possible association between SARS-CoV-2, ACE2, TMPRSS2, and skin manifestations

A new study analyzed the possibility of penetration of SARS-CoV-2 into the skin.

5 Sep 2022

Virtual screening and molecular dynamics explore potential repurposed drugs against monkeypox virus

A recent study investigated ‘targets’ in the poxvirus and identified the protein residues active in MPV, following which eight potential anti-viral drugs were proposed.

25 Aug 2022

New insights into the understanding of how ApoE variants contribute to Tau pathology in Alzheimer’s disease

Researchers examined the impact of tau neuropathology of APOE3 Christchurch (APOE3ch) homozygote against Alzheimer’s disease.

8 Aug 2022

Human anti-desmoglein 2 levels are associated with COVID-19 severity

In a new study, researchers assessed the association between anti-desmoglein (DSG) 1, 2 and 3 auto-antibodies (auto-Abs) in acute and convalescent serum samples obtained from patients with COVID-19 of varying severity.

2 Aug 2022

Plasma myosin light chain 9 levels may be better predictor of COVID-19 severity than blood biomarkers

In a new study, researchers found elevated plasma levels of myosin light chain 9 (Myl9) in COVID-19 patients with a fatal disease.

2 Aug 2022

Are Mexican free-tailed bats a SARS-CoV-2 reservoir?

In a new study, investigators analyzed whether Mexican free-tailed bats were a SARS-CoV-2 reservoir.

21 Jul 2022

What is the role of a niclosamide-based organic/inorganic hybrid in the suppression of SARS-CoV-2 infections?

A new study involved the preparation of NIC-MgO and NIC-MgO-HPMC by solid-state intercalation reaction followed by cetrimonium bromide (CTAB) stabilized NIC-MgO and MgO Nanoparticles (NP) preparation.

20 Jul 2022

Experimental model reveals possible causes and treatments for long-COVID

In a recent study published in the journal Science Translational Medicine, researchers characterized long-term pulmonary consequences of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) mouse-adapted strain (MA10) infection in BALB/c laboratory mice.

11 Jul 2022

Immunohistochemistry News and Research

Further Reading

Could COVID-19 infections trigger a relapse of mycosis fungoides or other cutaneous T-cell lymphomas?

New partnership creates an automated anatomic pathology slide-scanning solution

Neonatal mice-based model established that allows for the transmission of clinical SARS-CoV-2 isolates

Study links pancreatic cancer survival outcomes with arrangement of immune cells in tumors

Brazilian study reveals the effects of SARS-CoV-2 infection on the central nervous system

SARS-CoV-2 spike protein and messenger ribonucleic acid found to translocate into the nucleus

Virology of the human monkeypox virus

Signal transduction via the EGFR pathway likely to be involved in lenvatinib resistance

How does SARS-CoV-2 affect the male genitourinary system?

The possible association between SARS-CoV-2, ACE2, TMPRSS2, and skin manifestations

Virtual screening and molecular dynamics explore potential repurposed drugs against monkeypox virus

New insights into the understanding of how ApoE variants contribute to Tau pathology in Alzheimer’s disease

Human anti-desmoglein 2 levels are associated with COVID-19 severity

Plasma myosin light chain 9 levels may be better predictor of COVID-19 severity than blood biomarkers

Are Mexican free-tailed bats a SARS-CoV-2 reservoir?

What is the role of a niclosamide-based organic/inorganic hybrid in the suppression of SARS-CoV-2 infections?

Experimental model reveals possible causes and treatments for long-COVID

Characterization of longer-term effects on behavior and brain inflammation following recovery from mild COVID-19

COVID-19 and brain damage explained

Immune response triggered by COVID-19 damages the brain's blood vessels to cause neurological complications

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