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Points to consider: Should germline genetic testing be offered to all patients with breast cancer?

Should germline genetic testing be offered to all patients with breast cancer? The American College of Medical Genetics and Genomics addresses this important question in a new statement published in Genetics in Medicine, "Points to Consider: Is There Evidence to Support BRCA1/2 and Other Inherited Breast Cancer Genetic Testing for All Breast Cancer Patients? A Statement of the American College of Medical Genetics and Genomics."

13 Dec 2019

ACMG recommends evaluations of breast cancer patients before genetic testing

According to a statement on behalf of the American College of Medical Genetics and Genomics (ACMG) published Dec. 13 in the organization's official journal, Genetics in Medicine, there is insufficient evidence to recommend universal genetic testing for BRCA1/2 alone or in combination with multi-gene panels for all breast cancer patients.

13 Dec 2019

New drug combo promises help for triple negative breast cancer patients

A new preclinical study on triple negative breast cancer (TNBC) reports that an experimental polo-like kinase 1 (PLK1) inhibitor shrank tumor four times more powerfully when used along with standard drugs than alone. The study, reported in the journal PLOS ONE, opens up a new door of opportunity for patients with this disease.

11 Dec 2019

Combination regimen shows promising results in preclinical models of triple negative breast cancer

Tumor volume in a preclinical model of triple negative breast cancer (TNBC) was reduced four times more when an experimental polo-like kinase 1 (PLK1) inhibitor was combined with a standard-of-care chemotherapeutic agent than when the agent was used alone.

10 Dec 2019

Trial investigating "abortion pill reversal" stops due to safety concerns

Scientists are calling for pro-life US states to abolish an unproven medication that supposedly "reverses" medical abortion.

9 Dec 2019

Researchers confirm two new prognostic markers for triple negative breast cancer

Physicians who treat patients with triple negative breast cancer have two new ways to predict which patients may benefit most from the well-established post-surgery treatment known as AC chemotherapy, short for adjuvant doxorubicin and cyclophosphamide.

5 Dec 2019

A 'once a month' birth control pill

Birth control pills in their present form need to be taken once a day each day for the whole menstrual cycle. Other options such as Intra-Uterine devices (IUDs) or implanted progesterone offer a longer coverage, but most women prefer the pills due to their reliability and cheaper, easier and safer usage profile.

5 Dec 2019

Birth control pills shrink hypothalamus

Birth control pills have been found to reduce a part of the brain that is associated with controlling the sex drive finds a new study. The study results are being presented as a preview in the annual conference of the Radiological Society of North America (RSNA).

5 Dec 2019

Breast-conserving treatment may be a viable alternative to mastectomy, study suggests

Approximately 10% of breast cancer patients treated with lumpectomy (breast-conserving surgery [BCS]) and whole-breast radiation (WBI) will have a subsequent in-breast local recurrence of cancer (IBTR) when followed long term.

22 Nov 2019

Recently discovered protein may play key role in obesity and metabolic disease

With unexpected findings about a protein that's highly expressed in fat tissue, scientists at Scripps Research have opened the door to critical new understandings about obesity and metabolism.

21 Nov 2019

Low libido in older women not just down to menopause

Menopause marks the end of a woman’s reproductive years. Along with it, comes various effects, including irregular to the complete cessation of periods, insomnia, mood swings, irritability, hot flushes, and decreased sexual drive.

20 Nov 2019

Promising method to identify aggressive breast cancers that will respond to immunotherapy

University of North Carolina Lineberger Comprehensive Cancer Center researchers have discovered a promising method to identify aggressive breast cancer tumors that will respond to drugs that unleash the immune system against cancer.

14 Nov 2019

Fresh light on why aggressive breast tumors form and how they can be treated

New research presented at the Society for Endocrinology annual conference in Brighton appears to identify novel methods of therapy for an aggressive type of breast cancer as well as uncovering potential causative factors. The focus of the study is to show how common chemicals present in our surroundings are possibly putting women at risk of a type of breast cancer called triple negative breast cancer (TNBC).

12 Nov 2019

Contraceptive drug effective in preventing and regressing cervical cancer in mice

A new study in The American Journal of Pathology, published by Elsevier, reports that medroxyprogesterone acetate (MPA), the active ingredient in the common contraceptive injection Depo-Provera, was effective in preventing the development of cervical cancer in mice with precancerous lesions.

12 Nov 2019

Advice to pull a drug used to prevent premature birth sparks controversy

It has been recommended that a drug currently used to prevent preterm birth should be removed from the market.

6 Nov 2019

Link found between unique brain cells and OCD, anxiety

According to the National Institute of Mental Health, 1 in 3 people experience debilitating anxiety-;the kind that prevents someone from going about their normal life.

22 Oct 2019

Study highlights practice patterns and factors associated with prognosis of male breast cancer

A recent analysis reveals that treatment of male breast cancer has evolved over the years. In addition, certain patient-, tumor-, and treatment-related factors are linked with better survival. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

7 Oct 2019

Understanding treatment and prognosis of male breast cancer

October is Breast Cancer Awareness Month, an annual campaign to raise awareness about the potentially-fatal disease. Breast cancer is known as an illness that affects mostly women, but about 1 percent of all breast cancers affect men, too.

7 Oct 2019

Novel drug may be the answer in battling resistance in aggressive breast cancer

Breast cancer is one of the most frequently diagnosed cancers in women across the globe. It represents one in four of all cancers in women. The survival rates for breast cancer vary across the globe, but when it comes to the metastatic or advanced breast cancer type, it is currently incurable, but there are many treatments available.

7 Oct 2019

Presence of XX sex chromosomes increases risk of heart attacks and coronary artery disease

New research at the University of Kentucky has confirmed that the presence of XX sex chromosomes increases the amount of fat circulating in the blood, which leads to narrowing of the arteries and ultimately a higher risk of heart attacks and coronary artery disease.

3 Sep 2019

Progesterone News and Research

Points to consider: Should germline genetic testing be offered to all patients with breast cancer?

ACMG recommends evaluations of breast cancer patients before genetic testing

New drug combo promises help for triple negative breast cancer patients

Combination regimen shows promising results in preclinical models of triple negative breast cancer

Trial investigating "abortion pill reversal" stops due to safety concerns

Researchers confirm two new prognostic markers for triple negative breast cancer

A 'once a month' birth control pill

Birth control pills shrink hypothalamus

Breast-conserving treatment may be a viable alternative to mastectomy, study suggests

Recently discovered protein may play key role in obesity and metabolic disease

Low libido in older women not just down to menopause

Promising method to identify aggressive breast cancers that will respond to immunotherapy

Fresh light on why aggressive breast tumors form and how they can be treated

Contraceptive drug effective in preventing and regressing cervical cancer in mice

Advice to pull a drug used to prevent premature birth sparks controversy

Link found between unique brain cells and OCD, anxiety

Study highlights practice patterns and factors associated with prognosis of male breast cancer

Understanding treatment and prognosis of male breast cancer

Novel drug may be the answer in battling resistance in aggressive breast cancer

Presence of XX sex chromosomes increases risk of heart attacks and coronary artery disease

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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