Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Cellular protein signal can be manipulated to favor bone building

In experiments in rats and human cells, Johns Hopkins Medicine researchers say they have added to evidence that a cellular protein signal that drives both bone and fat formation in selected stem cells can be manipulated to favor bone building.

7 Jan 2019

Study of rare uterine sarcoma reveals clinically relevant molecular subtypes

Undifferentiated uterine sarcoma is a very rare but extremely aggressive cancer type. It can be divided into four groups with different characteristics of clinical importance - a new study at Karolinska Institutet reveals.

7 Jan 2019

Faulty immune receptor in HIV patients could be reason why many experience complications

For HIV patients, treatments that control the infection have come a long way. But many still struggle with a host of other disease-related complications such as neurocognitive disorders, cardiovascular issues, diabetes and chronic inflammation.

7 Jan 2019

Scientists identify new bat-borne virus related to Ebola

Researchers from Singapore's Duke-NUS Medical School, in collaboration with scientists in China, have identified and characterized a new genus of filovirus from a Rousettus bat in China. Their findings were published in the journal Nature Microbiology.

7 Jan 2019

Johns Hopkins researchers identify new marker for early detection of colorectal cancers

Johns Hopkins researchers have identified a protein involved in cell proliferation and the development of new blood vessels that could serve as a marker for the early detection of colorectal cancers.

7 Jan 2019

First viable mouse model of Hirschsprung's disease developed

About one in every 5,000 babies is born without enteric neurons in distal colon resulting in Hirschsprung's disease. Because of the lacking neurons, contents of the gut cannot pass normally resulting in constipation and enlargement of colon.

7 Jan 2019

Alzheimer's pathophysiology shows racial disparities

A study has identified racial disparities between African-Americans and Caucasians in the way in which Alzheimer’s disease arises and develops.

7 Jan 2019

Newly discovered biomarkers can help identify heart condition in patients who have three 'clinical risks'

Researchers at the University of Birmingham have found two biomarkers that could be used to identify a heart condition known as atrial fibrillation in patients who have three 'clinical risks'.

7 Jan 2019

New, potential therapy can disrupt myeloid cells that promote tumor growth

Cancerous tumors trick myeloid cells, an important part of the immune system, into perceiving them as a damaged part of the body; the tumors actually put myeloid cells to work helping them grow and metastasize (spread).

7 Jan 2019

Common food additive could cause celiac disease, review says

Research suggests that celiac disease could be caused by a bacterial enzyme used to manufacture sausages, cheese, bread and other processed foods.

7 Jan 2019

Inhalable mRNA offers hope for patients with lung disease

Scientists have reported the success of an inhalable mRNA therapy that can induce the production of a target protein in the lungs of mice.

4 Jan 2019

A small protein plays key role in how cancer stem cells differentiate

A jagged little protein appears to be key to how cancer stem cells differentiate and enable metastasis, according to researchers at Rice University and the Duke University School of Medicine.

4 Jan 2019

Research illuminates abilities of ADAR1 to ‘hyper-mutate’ tumor suppressor RNAs in leukemia

Writing in the January 3 issue of Cancer Cell, researchers at University of California San Diego School of Medicine report that detection of "copy editing" by a stem cell enzyme called ADAR1, which is active in more than 20 tumor types, may provide a kind of molecular radar for early detection of malignancies and represent a new therapeutic target for preventing cancer cell resistance to chemotherapy and radiation.

3 Jan 2019

Researchers develop new method of analysis to map cellular locations of proteins

Researchers at Karolinska Institutet and SciLifeLab have developed a new method of analysis that maps the location of proteins in the cell. The information has been compiled in a database that is accessible to researchers around the world.

3 Jan 2019

Commonly prescribed ADHD drug unlikely to increase cardiovascular risks in children

With more than 1.8 million children in the U.S. being treated annually with drugs for attention deficit hyperactivity disorder, the possibility that such drugs could damage their hearts has been a significant cause of concern for parents and physicians alike.

3 Jan 2019

Bulldogs' screw tails linked to rare inherited syndrome in humans

With their small size, stubby faces and wide-set eyes, bulldogs, French bulldogs and Boston terriers are among the most popular of domestic dog breeds. Now researchers at the University of California, Davis, School of Veterinary Medicine have found the genetic basis for these dogs' appearance, and linked it to a rare inherited syndrome in humans.

3 Jan 2019

Fruit fly study sheds light on the evolution of metabolism

Diet choice of animal species is highly variable. Some are specialists feeding only on one food source, such as a sugar-rich fruit or protein-rich meat. Other species, like humans, are generalists that can feed on different kinds of food sources.

3 Jan 2019

New medications provide better treatment for alcohol use disorders, chronic pain, mood disorders

Helping people with addictions has become a research passion for Purdue University's Richard van Rijn, who is leading a team to make drug discoveries to support millions around the world dealing with alcohol use disorders, chronic pain and mood disorders.

3 Jan 2019

Researchers reveal cause of possible genetic problems in mitochondria

A group of researchers from the Andalusian Centre for Molecular Biology and Regenerative Medicine has revealed the importance of eliminating any excess of defective products that might have accumulated in the mitochondria, as its presence generates mitochondrial instability and information loss on the mitochondrial genome.

3 Jan 2019

Study provides new insight into generation of new neurons in adulthood

Researchers at Sahlgrenska Academy at the University of Gothenburg, Sweden, in collaboration with research groups in Finland, Canada, and Slovenia, have discovered a novel and unexpected function of nestin, the best known marker of neural stem cells.

3 Jan 2019