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Proof that proteins can be custom-designed

Ever since the advent of recombinant-DNA technology, scientists have conceived that it will be feasible to create entirely new enzymes for specific needs.

27 Jan 2006

Treatment of down syndrome in mice restores nerve growth in cerebellum

Researchers at Johns Hopkins restored the normal growth of specific nerve cells in the cerebellum of mouse models of Down syndrome (DS) that were stunted by this genetic condition. The cerebellum is the rear, lower part of the brain that controls signals from the muscles to coordinate balance and motor learning.

25 Jan 2006

New treatment trials for autosomal dominant polycystic kidney disease

The National Institutes of Health (NIH) and the PKD Foundation have launched two treatment trials for autosomal dominant polycystic kidney disease (ADPKD).

25 Jan 2006

Researchers use new approach to 'break the code' for liver cancer test

Scientists at Birmingham University are using cutting edge technologies to move closer to a blood test that will improve early diagnosis of liver cancer in high risk groups, according to research published in the British Journal of Cancer.

25 Jan 2006

HIV revealed in 3D

HIV, the virus which leads to AIDS and which affects 40 million people across the world, has been seen in 3D detail for the first time by Oxford scientists and their colleagues in Heidelberg and Munich.

25 Jan 2006

Major companies in food recalls over mislabeling

It has been reported that food manufacturer Heinz has had to recall some of it's Weight Watchers products because the contents are not those specified on the labels.

25 Jan 2006

University of Florida researchers restore vitality to cells in lab experiments

University of Florida researchers say primitive cells that act like molecular maintenance men - traveling throughout the body to repair damaged blood vessels - become too rigid to move in patients with diabetes, fueling the disease's vascular complications.

25 Jan 2006

Researchers use yogurt to fight AIDS

Researchers have come up with a novel delivery system for anti-AIDS drugs: milk-curdling bacteria used to make yogurt and cheese.

25 Jan 2006

New tool for genetic research

In an article appearing online today in the journal Nature Methods, researchers at the EPFL (Ecole Polytechnique Fidirale de Lausanne) unveil a powerful new tool that will facilitate genetic research and open up new avenues for the clinical treatment of genetic disease.

23 Jan 2006

$Warfarin increases risk of bone fracture$

Warfarin increases risk of bone fracture

Elderly patients taking the commonly prescribed blood thinner warfarin experience an increased risk for osteoporosis-linked bone fractures, according to a study at Washington University School of Medicine in St. Louis.

23 Jan 2006

Symposium on celiac disease

A scientific symposium on celiac disease, "Genetic and Immune Mechanisms in Celiac Disease," will be held at the University of California, San Diego (UCSD) School of Medicine on Friday, February 10, from 8:30 a.m. to 12 noon. The symposium, hosted by UCSD’s newly established William K. Warren Medical Research Center for Celiac Disease, will be held at the university’s Center for Molecular Genetics conference room.

23 Jan 2006

Bidirectional behavioral plasticity of memory reconsolidation depends on amygdalar protein kinase A

When activated, a specific protein in the brain enhances long-term storage of fearful memories and strengthens previously established fearful memories, Yale School of Medicine researchers report this week in Nature Neuroscience.

23 Jan 2006

Gene therapy to turn off Parkinson's

A group of Northwestern University researchers is developing a novel gene therapy aimed at selectively turning off one of the genes involved in the development of Parkinson's disease.

23 Jan 2006

New method to find new metabolites

Ever since penicillin, a byproduct of a fungal mold, was discovered in 1929, scientists have scrutinized fungi for other breakthrough drugs. As reported Jan. 20 in the Journal of Chemistry and Biology, a team led by a University of Wisconsin-Madison researcher has developed a new method that may speed the ongoing quest for medically useful compounds in fungi.

23 Jan 2006

FDA fast track status for Alfimeprase

Nuvelo Inc. today announced that it has been granted fast track designation by the U.S. Food and Drug Administration (FDA) for its lead product candidate, alfimeprase, for the treatment of acute peripheral arterial occlusion (PAO), or "leg attack."

23 Jan 2006

Scientists discover method to multiply an adult stem cell 30-fold

Adult stem cells may be free of the ethical concerns that hamper embryonic stem cell research, but they still pose formidable scientific challenges.

23 Jan 2006

Protein amplifies DNA injury signals - cues genetic repair mechanism to prevent tumors

A Mayo Clinic-led research collaboration has discovered that the protein MDC1 amplifies weak DNA injury signals so genetic repair can begin.

23 Jan 2006

Ataxia gene identified

Researchers at the University of Minnesota Medical School have discovered the gene responsible for a type of ataxia, an incurable degenerative brain disease affecting movement and coordination.

23 Jan 2006

Histidine may be key to new therapies for cardiovascular disease

It's just one little amino acid, but it makes all the difference in protecting the heart from the harmful effects of heart attack and cardiac failure. Researchers from the University of Michigan Medical School suggest this amino acid, called histidine, could be the key to a new therapy for cardiovascular disease

23 Jan 2006

First genome-wide screen for protein complexes is completed

Researchers in Germany have finished the first complete analysis of the "molecular machines" in one of biology's most important model organisms: S. cerevisiae (baker's yeast). The study from the biotechnology company Cellzome, in collaboration with the European Molecular Biology Laboratory (EMBL), appears in this week's online edition of Nature.

23 Jan 2006