Laboratory News and Research

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Blood-brain barrier following stoke prevents harmful substances entering brain

Following ischemic stroke, the integrity of the blood-brain barrier (BBB), which prevents harmful substances such as inflammatory molecules from entering the brain, can be impaired in cerebral areas distant from initial ischemic insult.

27 Mar 2014

Carbon nanotube paper offers potential to miniaturize mass spectrometers

Nanotechnology is advancing tools likened to Star Trek's "tricorder" that perform on-the-spot chemical analysis for a range of applications including medical testing, explosives detection and food safety.

27 Mar 2014

Research may lead the way toward new treatments for proliferative retinopathies

A new report published online in The FASEB Journal may lead the way toward new treatments or a cure for a common cause of blindness (proliferative retinopathies). Specifically, scientists have discovered that the body's innate immune system does more than help ward off external pathogens.

27 Mar 2014

Study: Guinea pigs and mice can be replaced with non-animal skin sensitization method

Guinea pigs and mice can be replaced with a non-animal skin sensitization method that uses a human-derived skin model, according to a study presented today by the PETA International Science Consortium, Ltd., at the Society of Toxicology's annual meeting.

27 Mar 2014

Beer marinade help reduce formation of harmful substances in grilled meats

The smells of summer - the sweet fragrance of newly opened flowers, the scent of freshly cut grass and the aroma of meats cooking on the backyard grill - will soon be upon us.

27 Mar 2014

Mephedrone drug causes acute withdrawal symptoms, shows study

Contrary to popular belief among recreational drug users, mephedrone has several important differences when compared with MDMA, commonly known as ecstasy.

27 Mar 2014

Researchers evaluate influence of gut microbes on function of immune cells

New research suggests that gut microorganisms do not merely influence immune cell function, but also support the production of immune cells that form the first line of defense against infection.

27 Mar 2014

Adaptimmune awarded £2.1 million grant to expedite development of engineered T cell therapy

Adaptimmune today announced that it has been awarded a grant of £2.1 million from the Biomedical Catalyst Fund, managed by the UK’s innovation agency the Technology Strategy Board and the Medical Research Council. The prestigious award will expedite the development of Adaptimmune’s second engineered T cell therapy programme into the clinic in triple negative breast cancer.

26 Mar 2014

Study explores dangers of switching from MDMA to mephedrone

Contrary to popular belief among recreational drug users, mephedrone has several important differences when compared with MDMA, commonly known as ecstasy. These differences mean that mephedrone could leave a user with acute withdrawal symptoms and indicate that it may have a higher potential for developing dependence than MDMA according to a study published in British Journal of Pharmacology.

26 Mar 2014

Research findings point to potential biomarkers for early detection of at-risk youth

Researchers at the University of California, San Diego School of Medicine have discovered impaired neuronal activity in the parts of the brain associated with anticipatory functioning among occasional 18- to 24-year-old users of stimulant drugs, such as cocaine, amphetamines and prescription drugs such as Adderall.

26 Mar 2014

Adult day care services may protect family caregivers against harmful effects of stress

Family caregivers show an increase in the beneficial stress hormone DHEA-S on days when they use an adult day care service for their relatives with dementia, according to researchers at Penn State and the University of Texas at Austin.

26 Mar 2014

Singulex signs agreement to co-develop the Sgx Clarity system with Tecan

Singulex, Inc., the developer and leading provider of Single Molecule Counting (SMC) technology for clinical diagnostics and scientific discovery, today announced an agreement to co-develop the Sgx Clarity system with Tecan, a leading global provider of laboratory automation instruments.

From Tecan 25 Mar 2014

The Center for Applied Nanotechnology presents a ready-to-use reagent for the detection of poly-histidine tagged proteins in Blot assays

The nano-experts from the Center for Applied Nanotechnology (CAN) GmbH expand their product portfolio by CANdots® Series G - His Detect, which is a ready-to-use reagent for the detection of poly-histidine tagged proteins in Blot assays. It is easy to handle, highly sensitive as well as time saving compared to standard methods available on the market, e.g. ECL.

25 Mar 2014

Researchers receive grants to advance work in prevention of premature birth

Researchers at UT Southwestern Medical Center received grants totaling $600,000 from the March of Dimes Foundation to advance their work in the prevention of premature birth, which affects about one out of nine babies born annually in the U.S. and is the leading cause of newborn death.

25 Mar 2014

Researchers discover novel population of neutrophils that exhibit enhanced microbial killing activity

Case Western Reserve University researchers have discovered a novel population of neutrophils, which are the body's infection control workhorses. These cells have an enhanced microbial killing ability and are thereby better able to control infection.

25 Mar 2014

XBP1 gene plays pivotal role in the growth and progression of triple negative breast cancer

Scientists from Weill Cornell Medical College and Houston Methodist have found that a gene previously unassociated with breast cancer plays a pivotal role in the growth and progression of the triple negative form of the disease, a particularly deadly strain that often has few treatment options. Their research, published in this week's Nature, suggests that targeting the gene may be a new approach to treating the disease.

25 Mar 2014

Researchers develop one-step analysis for detecting tumor markers in blood

Benign growth, or cancer? Tumor markers in the blood help determine whether the patient is afflicted with a malign tumor and whether it is excreting markers more vigorously - involving highly specific proteins. An increased concentration in the blood provides one indication of the disease for physicians. However, it has been quite expensive in time and effort to detect the markers thus far. This is because all kinds of molecules and proteins are teeming in the blood. To be able to detect a single specific one, doctors must first separate and purify the blood in several steps, and then isolate the marker they are searching for from the rest of the molecules.

25 Mar 2014

Marina Cavazzana, Adrian J. Thrasher honored with Pioneer Award for gene therapy

Marina Cavazzana, MD, PhD, Paris Descartes University, France and Adrian J. Thrasher, MD, PhD, University College London Institute of Child Health, UK, have been honored with the Pioneer Award for basic and clinical gene therapy for immunodeficiency disorders.

25 Mar 2014

Researchers use retro approach to produce new drugs

This alternative approach to creating artificial organic molecules, called bioretrosynthesis, was first proposed four years ago by Brian Bachmann, associate professor of chemistry at Vanderbilt University. Now Bachmann and a team of collaborators report that they have succeeded in using the method to produce the HIV drug didanosine.

25 Mar 2014

Patrys provides update on development programme for anti-cancer product, PAT-LM1

Patrys Limited, a clinical stage biotechnology company, is pleased to provide an update on the development programme for anti-cancer product, PAT-LM1.

24 Mar 2014

Laboratory News and Research

Blood-brain barrier following stoke prevents harmful substances entering brain

Carbon nanotube paper offers potential to miniaturize mass spectrometers

Research may lead the way toward new treatments for proliferative retinopathies

Study: Guinea pigs and mice can be replaced with non-animal skin sensitization method

Beer marinade help reduce formation of harmful substances in grilled meats

Mephedrone drug causes acute withdrawal symptoms, shows study

Researchers evaluate influence of gut microbes on function of immune cells

Adaptimmune awarded £2.1 million grant to expedite development of engineered T cell therapy

Study explores dangers of switching from MDMA to mephedrone

Research findings point to potential biomarkers for early detection of at-risk youth

Adult day care services may protect family caregivers against harmful effects of stress

Singulex signs agreement to co-develop the Sgx Clarity system with Tecan

The Center for Applied Nanotechnology presents a ready-to-use reagent for the detection of poly-histidine tagged proteins in Blot assays

Researchers receive grants to advance work in prevention of premature birth

Researchers discover novel population of neutrophils that exhibit enhanced microbial killing activity

XBP1 gene plays pivotal role in the growth and progression of triple negative breast cancer

Researchers develop one-step analysis for detecting tumor markers in blood

Marina Cavazzana, Adrian J. Thrasher honored with Pioneer Award for gene therapy

Researchers use retro approach to produce new drugs

Patrys provides update on development programme for anti-cancer product, PAT-LM1

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