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Stem cell microenvironment reverses malignant melanoma

Northwestern University researchers have demonstrated how the microenvironments of two human embryonic stem cell (hESC) lines (federally approved) induced metastatic melanoma cells to revert to a normal, skin cell-like type with the ability to form colonies similar to hESCs.

20 Nov 2005

Scientists direct embryonic stem cells to become cartilage cells

Scientists from Imperial College London have successfully converted human embryonic stem cells into cartilage cells, offering encouragement that replacement cartilage could one day be grown for transplantation.

20 Nov 2005

Study reveals how T cells analyze and react to the signals of infection at the immunological synapse

The immune system is highly complex. The cast of characters alone required to marshal an immune response to a foreign invader can number in the millions as the body's soldiers, T cells, are called into action.

20 Nov 2005

Plant extract forskolin may lead to leukemia treatment

Scientists here have identified a new pathway in the progression of chronic myelogenous leukemia (CML). They also discovered that an extract from the root of a common ornamental plant can suppress the process.

20 Nov 2005

Forget decaf - coffee full of caffeine is much healthier!

Contrary to the hype the public has often been led to believe, a new study has revealed that decaffeinated coffee may be worse for the health than the caffeine rich kind.

20 Nov 2005

Six gene variants predict heart muscle damage after cardiac surgery

Duke University Medical Center researchers have found that patients with six specific variants of genes involved in the body's immune response are significantly more likely to suffer damage of heart tissue after cardiac surgery.

16 Nov 2005

Haphazard activation of secondary signaling pathways may fuel cancer's genesis

When found at abnormally high concentrations, two proteins implicated in many human cancers have the potential to spur indiscriminate biochemical signaling inside cells, chemists at Harvard University have found.

16 Nov 2005

Decaffeinated coffee may cause an increase in harmful LDL cholesterol

Decaffeinated -- not caffeinated -- coffee may cause an increase in harmful LDL cholesterol by increasing a specific type of blood fat linked to the metabolic syndrome, hints a new study presented at the American Heart Association's Scientific Sessions 2005.

16 Nov 2005

Scientists use stem cells to grow cartilage

16 Nov 2005

World first trial grows blood vessels from patient's own skin

A team of American scientists have successfully implanted blood vessels grown entirely from a patient's own cells.

16 Nov 2005

Gene therapy potential of the protein vasostatin for treatment of pancreatic cancer

A gene responsible for the production of a protein called vasostatin may prove a promising new way of treating pancreatic cancer, suggests research published ahead of print in Gut.

15 Nov 2005

Lack of aggressive treatment for clogged leg blood vessels means missed heart attack prevention opportunity

Despite the fact that clogged arteries in the legs usually mean clogged arteries near the heart, doctors often fail to give heart-protecting drugs to people with severe leg blood vessel blockages, a new University of Michigan-led study finds.

15 Nov 2005

Torcetrapib - Lipitor drug combo shows promise

According to drug company Pfizer the results of two mid-stage studies on its experimental cholesterol drug torcetrapib, combined with its cholesterol drug Lipitor, were so promising that the company will continue into the final stage.

15 Nov 2005

Vietnamese researchers say bird flu already resisant to Tamiflu

Scientists in Vietnam are concerned that the deadly bird flu may have infected two more people, and they suspect the virus may have mutated into a more dangerous form which could spread in mammals, and cause outbreaks in poultry.

15 Nov 2005

Better understanding of cancer cachexia

New research shows that a wasting condition responsible for nearly a third of all cancer deaths involves the loss of an essential muscle protein that is also lost in people with muscular dystrophy.

15 Nov 2005

Nerve-cell dendrites splice messenger RNA

Researchers at the University of Pennsylvania School of Medicine have discovered that nerve-cell dendrites have the capacity to splice messenger RNA (pre-mRNA), a process once believed to only take place in the nucleus of cells.

14 Nov 2005

Olfactory epithelium plays a critical role in pheromone detection

Howard Hughes Medical Institute researchers have discovered that pheromones essential for mating behavior in mice are recognized by the nose and not by the vomeronasal system, as researchers had long suspected.

14 Nov 2005

New respiratory synctial virus treatment for at-risk infants under study

A new, enhanced-potency onoclonal antibody designed to keep the sniffles from turning into a devasting illness in at-risk babies is under study at the Medical College of Georgia Children's Medical Center.

14 Nov 2005

Protein discovery may have implications for treating E. coli 0157:H7 infection

A discovery by Queen's researchers of a previously unknown protein may open the door to more effective treatment of a deadly strain of the E. coli bacteria.

14 Nov 2005

Why the bird flu virus H5N1 is so deadly to humans

A study published today in the open access journal Respiratory Research reveals that, in human cells, the virus can trigger levels of inflammatory proteins more than 10 times higher than the common human flu virus H1N1.

14 Nov 2005