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Researchers unravel novel mechanism of estrogen action on heart physiology

Estrogens are powerful hormones important for the formation and function of the nervous, reproductive and cardiovascular systems.

6 Dec 2017

TUM scientists discover emergency shut-off switch for T cell Non-Hodgkin's lymphoma

Safety switches that automatically stop the device for example before it overheats are built into many electrical appliances. Cells are also equipped with such "emergency stop" functions. They make sure that a defective cell doesn't become a tumor cell.

6 Dec 2017

Reducing mitochondrial protein in cardiac muscle cells initiates heart failure

Reducing a protein found in the mitochondria of cardiac muscle cells initiates cardiac dysfunction and heart failure, a finding that could provide insight for new treatments for cardiovascular diseases, a study led by Georgia State University has shown.

6 Dec 2017

Specific protein negatively affects pancreatic cells and leads to cancer growth

Pancreatic cancer is one of the most aggressive forms of cancer and is currently very difficult to treat. However, the last few years have seen advances in the scientific understanding of how this cancer develops at a molecular level.

6 Dec 2017

Scientists create low-cost, rapid test to detect iron and vitamin A deficiencies

Cornell University engineers and nutritionists have created a swift solution for a challenging global health problem: a low-cost, rapid test to detect iron and vitamin A deficiencies at the point of care.

5 Dec 2017

Researchers identify way to prevent fat cells from growing larger

Researchers at Washington University School of Medicine in St. Louis have identified a way to prevent fat cells from growing larger, a process that leads to weight gain and obesity. By activating a pathway in fat cells in mice, the researchers found they could feed the animals a high-fat diet without making them obese.

5 Dec 2017

Immune-boosting drug combination may hold promise for treating ovarian cancer

Johns Hopkins Kimmel Cancer Center researchers demonstrated that mice with ovarian cancer that received drugs to reactivate dormant genes along with other drugs that activate the immune system had a greater reduction of tumor burden and significantly longer survival than those that received any of the drugs alone.

5 Dec 2017

Scientists reveal ‘anti-metastatic surveillance’ role of Caveolin-1 protein

A new study conducted at the VIB-KU Leuven Center for Cancer Biology in Belgium has labeled the protein Caveolin-1 as a high-potential pursuit in the fight against cancer.

5 Dec 2017

New small-molecule drug restores brain function, memory in mouse model of Alzheimer's disease

An international team of researchers has shown that a new small-molecule drug can restore brain function and memory in a mouse model of Alzheimer's disease.

5 Dec 2017

Investigational ZPIV vaccine found to be safe and immunogenic in trial participants

The investigational Zika purified inactivated virus (ZPIV) vaccine was well-tolerated and induced an immune response in participants, according to initial results from three Phase 1 clinical trials.

5 Dec 2017

Biological Applications of AFM

An interview with Samuel Lesko, European Applications Manager, Bruker Nano Surfaces conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 5 Dec 2017

Breakfast may lower risk of diabetes and heart disease, study says

A new study published in the Journal of Physiology suggests that regularly consuming breakfast affects our body fat cells by lowering the activity of genes involved in fat metabolism and increasing the amount of sugar they use up. According to the study, this may reduce the risk of diabetes and cardiovascular disease.

5 Dec 2017

DNA sequencing could identify genetic cause of kidney disease

DNA sequencing could soon become part of the routine diagnostic workup for patients with chronic kidney disease, suggests a new study from Columbia University Medical Center.

5 Dec 2017

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

There's a continued drive towards making in vitro assays ever more translational towards in vivo models and ultimately the clinic. This ties in with the resurgence of phenotypic screening and is a response to the perceived poor translation of the traditional simple cell-based assays, often developed to study just single protein targets.

From Sartorius 5 Dec 2017

Scientists investigate new role of old protein in breast cancer

Scientists led by Dr Chris Toseland of the University's School of Biosciences studied a protein called Myosin VI, a molecular motor which acts as a courier to transport other proteins within our cells.

4 Dec 2017

New treatment aims to target abnormally shaped protein in deadly childhood brain cancer

Children with an extremely deadly form of brain cancer might benefit from a new treatment that aims to direct an immune response against an abnormally shaped protein found exclusively on cancer cells, according to a new study led by UC San Francisco researchers.

4 Dec 2017

Protein C News and Research

Researchers unravel novel mechanism of estrogen action on heart physiology

TUM scientists discover emergency shut-off switch for T cell Non-Hodgkin's lymphoma

Reducing mitochondrial protein in cardiac muscle cells initiates heart failure

Specific protein negatively affects pancreatic cells and leads to cancer growth

Scientists create low-cost, rapid test to detect iron and vitamin A deficiencies

Researchers identify way to prevent fat cells from growing larger

Immune-boosting drug combination may hold promise for treating ovarian cancer

Scientists reveal ‘anti-metastatic surveillance’ role of Caveolin-1 protein

New small-molecule drug restores brain function, memory in mouse model of Alzheimer's disease

Investigational ZPIV vaccine found to be safe and immunogenic in trial participants

Biological Applications of AFM

Breakfast may lower risk of diabetes and heart disease, study says

DNA sequencing could identify genetic cause of kidney disease

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

Scientists investigate new role of old protein in breast cancer

New treatment aims to target abnormally shaped protein in deadly childhood brain cancer

Study reveals gene linked to metastatic melanoma

Malvern Panalytical Announce Efforts Towards a Platform For Protein Aggregation Profiling

Study points to possible targets for therapeutic intervention in the fight against ALS

Scientists study behavior of Listeria monocytogenes during asymptomatic infection

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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