Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Blocking activity of plasma protein can be possible way to protect against radiation-induced injury

It is possible to prevent certain injuries that can occur in radiation therapy against cancer. By blocking the activity of a plasma protein during and immediately after radiation, the patient can be protected against injury. This is shown in a new doctoral thesis at Umeå University, Sweden.

20 Nov 2018

Scientists identify novel target for neuron regeneration, functional recovery in spinal cord injury

Restoring the ability to walk following spinal cord injury requires neurons in the brain to reestablish communication pathways with neurons in the spinal cord.

20 Nov 2018

Scientists use cryo-EM to capture freeze-frames of molecule’s 'lock-and-load' on DNA

Pushing the limits of cryo-electron microscopy, University of California, Berkeley, scientists have captured freeze-frames of the changing shape of a huge molecule, one of the body's key molecular machines, as it locks onto DNA and loads the machinery for reading the genetic code.

20 Nov 2018

Study sheds light on the infection mechanism of influenza virus

New research has taken a step towards understanding how highly pathogenic influenza viruses such as deadly bird flu infect humans.

20 Nov 2018

New research offers hope for simpler way to diagnose and treat cancer

Monitoring cancer can often be an intrusive and exhausting process for patients. But with Brigham Young University chemistry professor Ryan Kelly's new research, there is hope for a simpler way: No more biopsies.

20 Nov 2018

Researchers identify multisystem disorder caused by bi-allelic variants in CCDC47 gene

Researchers and clinicians through a multicenter collaboration have identified a novel multisystem disorder caused by bi-allelic variants in the CCDC47 gene. Their findings are reported in the American Journal of Human Genetics.

20 Nov 2018

Location matters for inflammation clearance

Health conditions that involve inflammation run the gamut, from multiple sclerosis and lupus to arthritis, diabetes, and cancer. While inflammation can serve as a normal response to help the body deal with injury or infection, problems arise when it persists, potentially harming surrounding tissues.

20 Nov 2018

Researchers to explore the enigmatic role of unstructured protein in regulating circadian function

A new frontier in the science of circadian rhythms - whose disruption is linked to major diseases like cancer and diabetes - suggests a previously unknown mechanism at work in our daily biological cycle.

20 Nov 2018

New research project to combat obesity, type 2 diabetes receives NIH funding

A research project headed by a faculty member from the Ohio University Heritage College of Osteopathic Medicine, which will explore whether administering a protein that's produced in the body can help prevent obesity and type 2 diabetes, has received $464,145 in funding from the National Institutes of Health.

20 Nov 2018

New drug shows promise for treating people with peanut allergy

Controlled ingestion of peanut protein could help build tolerance in peanut allergy sufferers. Authors of a new study published in the New England Journal of Medicine say an oral immunotherapy drug they tested could be the first FDA-approved medication of its kind for people with peanut allergy.

19 Nov 2018

Receptor structure could be key to developing new osteoporosis drugs

Researchers at the University of Zurich have determined the three-dimensional structure of a receptor that controls the release of calcium from bones. The receptor is now one of the main candidates for developing new drugs to treat osteoporosis.

19 Nov 2018

RNAi therapy shown to alleviate preeclampsia in animal model

Researcher have used a small interfering RNA (siRNA) to reduce preeclampsia symptoms in an animal model. The approach could provide a new way of treating preeclampsia in humans.

19 Nov 2018

2PG Company receives grant to develop sensitive, low-cost molecular diagnostic tests for tuberculosis

Two Pore Guys, Inc. today announced that the company has received a $2.8 million grant from the Bill & Melinda Gates Foundation to develop sensitive, low-cost molecular diagnostic tests for tuberculosis using its solid-state nanopore technology.

19 Nov 2018

Researchers identify molecule to fight myotubular myopathy

Myotubular myopathy is a severe genetic disease that leads to muscle paralysis from birth and results in death before two years of age. Although no treatment currently exists, researchers from the University of Geneva, Switzerland, - working in collaboration with the University of Strasbourg, France, - have identified a molecule that not only greatly reduces the progression of the disease but also boosts life expectancy in animal models by a factor of seven.

19 Nov 2018

Study reveals impact of residual inflammatory risk on clinical outcomes after PCI

Patients who have persistently high levels of inflammation following percutaneous coronary intervention for coronary artery disease are significantly more likely to die from any cause or to have a heart attack within a year, according to a study of 7,026 patients published in the European Heart Journal.

19 Nov 2018

Researchers develop novel mouse model to study immunomodulatory therapies

Because mice do not respond to immunomodulatory drugs, preclinical therapeutic and safety studies of the effects of IMiDs have not been possible in existing types of mice.

19 Nov 2018

Artificial bone-like substance mimics the way real bone grows at atomic level

Researchers from Chalmers University of Technology, Sweden, have discovered how our bones grow at an atomic level, showing how an unstructured mass orders itself into a perfectly arranged bone structure.

19 Nov 2018

Scientists equip new virus that kills carcinoma cells with protein

Scientists have equipped a virus that kills carcinoma cells with a protein so it can also target and kill adjacent cells that are tricked into shielding the cancer from the immune system.

19 Nov 2018

Surprising discovery about BH4 may rekindle interest in once-promising pathway

In 2013, renowned Boston Children's Hospital pain researcher Clifford Woolf, MB, BCh, PhD, and chemist Kai Johnsson, PhD, his fellow co-founder at Quartet Medicine, believed they held the key to non-narcotic pain relief.

19 Nov 2018

Scientists discover new inhibitor that decreases lung inflammation

Scientists from the University of Sheffield have discovered a new inhibitor which decreases lung inflammation and could hold the key to treating Acute Respiratory Distress Syndrome - a life-threatening disease which affects thousands of people in the UK.

18 Nov 2018