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Clinical trial results could lead to treatment of heart disease in Duchenne muscular dystrophy patients

After boys and young men with Duchenne muscular dystrophy received cardiac progenitor cell infusions, medical tests indicated that the patients' hearts appeared improved, results from a new study show. Patients in the study also scored higher on arm strength tests after receiving the cell infusions.

15 Nov 2017

Scientists find key that allows neural differentiation of microRNA-deficient pluripotent stem cells

The more than 200 different types of human cells have the same DNA but express different ensembles of genes. Each cell type was derived from embryonic stem cells, which are called pluripotent stem cells because they can differentiate to all those different cell fates.

15 Nov 2017

Aggressive testing unnecessary for patients who go to ER with chest pain, study suggests

Patients who go to the emergency room (ER) with chest pain often receive unnecessary tests to evaluate whether they are having a heart attack, a practice that provides no clinical benefit and adds hundreds of dollars in health-care costs, according to a new study from researchers at Washington University School of Medicine in St. Louis.

15 Nov 2017

Researchers visualize mechanism of CRISPR-Cas9 genetic-engineering technique

Researchers at Kanazawa University and the University of Tokyo report in Nature Communications the visualization of the dynamics of ‘molecular scissors’ — the main mechanism of the CRISPR-Cas9 genetic-engineering technique.

15 Nov 2017

MDA announces 13 new research grants to advance treatment for neuromuscular diseases

The Muscular Dystrophy Association today announced 13 new research and development grants totaling $3.5 million to accelerate the development of treatments for muscular dystrophy, ALS and related life-threatening diseases.

14 Nov 2017

UCR-led research discovers that human protein could be used to treat sepsis

A research team led by a biomedical scientist at the University of California, Riverside has discovered that the human protein resistin could be used to treat sepsis, the body's extreme and uncontrolled immune response to an infection.

14 Nov 2017

Using AFM to study cancer cells

An interview with Prof. Hermann Schillers, Universität Münster conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 14 Nov 2017

New drug shows promise in mouse model of autism disorder

Scientists have performed a successful test of a possible new drug in a mouse model of an autism disorder. The candidate drug, called NitroSynapsin, largely corrected electrical, behavioral and brain abnormalities in the mice.

14 Nov 2017

Anti-parasite drug acts like tailored medicine against colon, prostate cancer

Medicine against parasites like Tapeworms and Giardia, contains a substance that kills Prostate- and colon cancer.

14 Nov 2017

Lower thresholds for blood transfusions proven safe and provide good patient outcomes

Lower thresholds for blood transfusions during cardiac surgery have proven to be safe and provide good patient outcomes compared to traditional thresholds, according to the largest research study ever performed in this area. The lower or "restrictive" threshold also can help reduce the amount of blood transfused and money spent for each procedure.

14 Nov 2017

Analysis finds simple method to identify patients most likely to benefit from long-term canakinumab treatment

A new analysis seeks to answer the question of which patients are likely to gain the greatest cardiovascular benefit when treated with the anti-inflammatory agent canakinumab.

14 Nov 2017

Scientists identify critical player in Alzheimer's disease pathogenesis

Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that a protein called membralin is critical for keeping Alzheimer's disease pathology in check.

14 Nov 2017

Scientists devise new way to control single neurons using optogenetics

Researchers at MIT and Paris Descartes University have developed a new optogenetic technique that sculpts light to target individual cells bearing engineered light-sensitive molecules, so that individual neurons can be precisely stimulated.

13 Nov 2017

Absence of VEGF-A in cancer-killing T cells accelerates tumor development

Contrary to what was previously believed, the immune system's cancer-killing T cells are more effective in a tumour's anoxic environment when they have access to growth factor VEGF-A.

13 Nov 2017

Specific way of spelling out genetic code likely allows viruses to evade our cellular defenses

For millions of years, humans and viruses have engaged in a constant tug of war: as our cells evolve new ways to defend us from our viral enemies, these pathogens in turn acquire new traits to sidestep those defenses.

13 Nov 2017

Scientists invent new way of folding and protecting recombinant proteins

A team from the NUS Yong Loo Lin School of Medicine has invented a fundamentally new way of folding and protecting recombinant proteins.

13 Nov 2017

Rapid blood test that spots heart attack risk could improve treatment of people with chest pain

A low-cost, rapid blood test that spots whether people are at risk of a heart attack could improve the treatment of people with chest pain at emergency departments around the world, a study suggests.

13 Nov 2017

Researchers find efficient way to produce neurons from pluripotent stem cells

Since their discovery in 2006, induced pluripotent stem cells are a glimmer of hope for many diseases. But further research of the complex regulation of pluripotent stem cell identity revealed unexpected difficulties.

13 Nov 2017

Scientists develop novel mouse model to capture pathology of sporadic ALS and FTD

Neurodegenerative diseases are incurable and debilitating conditions that result in progressive degeneration and death of nerve cells, which leads to problems with movement or mental functioning. Examples include Alzheimer's, Parkinson's, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

13 Nov 2017

Advances in genetic and stem cell techniques help identify therapeutic targets for neurological disorders

Research released today highlights advances in the use of CRISPR-Cas9 and human induced pluripotent stem cell technologies to identify novel therapeutic targets for neurological disorders such as schizophrenia and addiction.

13 Nov 2017

Protein C News and Research

Clinical trial results could lead to treatment of heart disease in Duchenne muscular dystrophy patients

Scientists find key that allows neural differentiation of microRNA-deficient pluripotent stem cells

Aggressive testing unnecessary for patients who go to ER with chest pain, study suggests

Researchers visualize mechanism of CRISPR-Cas9 genetic-engineering technique

MDA announces 13 new research grants to advance treatment for neuromuscular diseases

UCR-led research discovers that human protein could be used to treat sepsis

Using AFM to study cancer cells

New drug shows promise in mouse model of autism disorder

Anti-parasite drug acts like tailored medicine against colon, prostate cancer

Lower thresholds for blood transfusions proven safe and provide good patient outcomes

Analysis finds simple method to identify patients most likely to benefit from long-term canakinumab treatment

Scientists identify critical player in Alzheimer's disease pathogenesis

Scientists devise new way to control single neurons using optogenetics

Absence of VEGF-A in cancer-killing T cells accelerates tumor development

Specific way of spelling out genetic code likely allows viruses to evade our cellular defenses

Scientists invent new way of folding and protecting recombinant proteins

Rapid blood test that spots heart attack risk could improve treatment of people with chest pain

Researchers find efficient way to produce neurons from pluripotent stem cells

Scientists develop novel mouse model to capture pathology of sporadic ALS and FTD

Advances in genetic and stem cell techniques help identify therapeutic targets for neurological disorders

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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