Genetic Engineering News and Research

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Epigenetic switch can cause cancer, shows study

Cancer has long been thought to be primarily a genetic disease, but in recent decades scientists have come to believe that epigenetic changes - which don't change the DNA sequence but how it is 'read' - also play a role in cancer.

26 Jul 2014

New discovery links two important hypotheses in Alzheimer's disease research

In Alzheimer's disease, accumulation of amyloid plaque in the brain is believed to play an important role in many characteristic disease symptoms, including memory loss and other mental state changes.

22 Jul 2014

Viruses designed to kill cancer cells could boost effectiveness of chemotherapy to arms, legs

Viruses designed to target and kill cancer cells could boost the effectiveness of chemotherapy to the arms and legs and help avoid amputation, a new study reports.

22 Jul 2014

Researchers propose ‘microbiome cloud model’ to understand variation in individual's microbiome composition

The Human Microbiome Project (HMP) is a global initiative to identify and characterize the microorganisms present at multiple sites in the human body.

22 Jul 2014

FDA approves Ruconest for treatment of acute attacks in adolescent patients with HAE

The U.S. Food and Drug Administration yesterday approved Ruconest, the first recombinant C1-Esterase Inhibitor product for the treatment of acute attacks in adult and adolescent patients with hereditary angioedema (HAE).

18 Jul 2014

Splice-switching oligonucleotide drugs alter editing of gene transcript

In splice-switching, an innovative therapeutic approach, targeted oligonucleotide drugs alter the editing of a gene transcript to produce the desired form of a protein.

18 Jul 2014

New article describes about crowdsourcing and drug repurposing needs

Experimental drugs proven safe but perhaps not sufficiently effective in initial testing or against a first disease target may sit gathering dust on the shelves of pharmaceutical companies.

17 Jul 2014

New software-based method identifies patients with newly diagnosed HIV using EMRs

A new, validated software-based method for identifying patients with newly diagnosed HIV using electronic medical records (EMRs) is described in AIDS Research and Human Retroviruses, a peer-reviewed journal published by Mary Ann Liebert, Inc., publishers.

16 Jul 2014

CRISPR system involved in promoting antibiotic resistance

CRISPR, a system of genes that bacteria use to fend off viruses, is involved in promoting antibiotic resistance in Francisella novicida, a close relative of the bacterium that causes tularemia.

15 Jul 2014

Sunscreens do not protect totally against development of skin cancer, shows study

The researcher at the Neurosciences Institute, Joint Center of the University Miguel Hernández (UMH) in Elche and the Higher Council for Scientific Research (CSIC), Berta López Sánchez-Laorden co-authored a study that concluded that sunscreens do not protect totally against the development of skin cancer.

14 Jul 2014

Scientists develop RNA that binds cGMP

The transmission of signals within cells is dependent on cyclic guanosine monophosphate (cGMP) as an important secondary messenger. German scientists have now developed an RNA that binds cGMP. As reported in the journal Angewandte Chemie, it is possible to suppress the cGMP signal cascade in genetically modified cells that produce this RNA.

10 Jul 2014

Genetic mutations in liver cells may drive tumor formation in intrahepatic cholangiocarcinoma

Two genetic mutations in liver cells may drive tumor formation in intrahepatic cholangiocarcinoma (iCCA), the second most common form of liver cancer, according to a research published in the July issue of the journal Nature.

8 Jul 2014

Study examines whether men who ride have higher risk of erectile dysfunction, infertility, prostate cancer

Cycling is a popular activity that offers clear health benefits, but there is an ongoing controversy about whether men who ride have a higher risk of urogenital disorders such as erectile dysfunction, infertility, or prostate cancer.

8 Jul 2014

New study on root development can help select drought-resistant crops

Growing plants in a microscope is helping scientists to view roots developing in 3D and in real time.

4 Jul 2014

Discovery points the way to potential new strategies to treat blood disorders

Like a line of falling dominos, a cascade of molecular events in the bone marrow produces high levels of inflammation that disrupt normal blood formation and lead to potentially deadly disorders including leukemia, an Indiana University-led research team has reported.

4 Jul 2014

Loss of p62 protein in cells and tissue surrounding a tumor can influence tumor growth

A team of scientists from Sanford Burnham Medical Research Institute has found that the loss of a protein called p62 in the cells and tissue surrounding a tumor can enhance the growth and progression of tumors.

4 Jul 2014

genOway to provide EUCOMM conditional knockout mouse models to study human diseases

genOway, the biotechnology company dedicated to the development of genetically modified animal models, the Wellcome Trust Sanger Institute (UK) and Helmholtz Zentrum München (Germany), members of the EUCOMM Program (European Conditional Mouse Mutagenesis Program) and its successor program EUCOMMTOOLS (EUCOMM: Tools for functional annotation of the mouse genome) announce today the signing of a license enabling genOway to provide industry scientists with conditional knockout (KO) models developed by EUCOMM.

3 Jul 2014

Australian immunologists uncover additional role for antibody-making 'B cells'

A discovery by Australian immunologists, uncovering an additional role for antibody-making 'B cells', is considered important enough by the American Association of Immunologists to rank it among the top 10% of articles in the latest issue of The Journal of Immunology, off the press today.

2 Jul 2014

Researchers receive over $1M to study molecular foundations of pancreatic cancer

Alexandros Tzatsos, M.D., Ph.D., assistant professor of anatomy and regenerative biology at the George Washington University School of Medicine and Health Sciences, was awarded over one million dollars in grants from the National Institutes of Health to study the molecular foundations of pancreatic cancer.

1 Jul 2014

Switching off a single gene converts human gastrointestinal cells into insulin-producing cells

By switching off a single gene, scientists at Columbia University's Naomi Berrie Diabetes Center have converted human gastrointestinal cells into insulin-producing cells, demonstrating in principle that a drug could retrain cells inside a person's GI tract to produce insulin.

30 Jun 2014

Genetic Engineering News and Research

Epigenetic switch can cause cancer, shows study

New discovery links two important hypotheses in Alzheimer's disease research

Viruses designed to kill cancer cells could boost effectiveness of chemotherapy to arms, legs

Researchers propose ‘microbiome cloud model’ to understand variation in individual's microbiome composition

FDA approves Ruconest for treatment of acute attacks in adolescent patients with HAE

Splice-switching oligonucleotide drugs alter editing of gene transcript

New article describes about crowdsourcing and drug repurposing needs

New software-based method identifies patients with newly diagnosed HIV using EMRs

CRISPR system involved in promoting antibiotic resistance

Sunscreens do not protect totally against development of skin cancer, shows study

Scientists develop RNA that binds cGMP

Genetic mutations in liver cells may drive tumor formation in intrahepatic cholangiocarcinoma

Study examines whether men who ride have higher risk of erectile dysfunction, infertility, prostate cancer

New study on root development can help select drought-resistant crops

Discovery points the way to potential new strategies to treat blood disorders

Loss of p62 protein in cells and tissue surrounding a tumor can influence tumor growth

genOway to provide EUCOMM conditional knockout mouse models to study human diseases

Australian immunologists uncover additional role for antibody-making 'B cells'

Researchers receive over $1M to study molecular foundations of pancreatic cancer

Switching off a single gene converts human gastrointestinal cells into insulin-producing cells

eBook: Using iPSCs models for human disease research and drug discovery eBook

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Industry Focus eBook - Analytical Chemistry (3rd edition)

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