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Nuclear receptor proteins could change anti-inflammatory treatments

Several nuclear receptor proteins appear to overlap in their ability to exert anti-inflammatory effects, according to new research by scientists at the University of California, San Diego (UCSD).

12 Sep 2005

Amantadine resistant avian influenza viruses more common in Southeast Asia than North America

Resistance to the antiviral drug amantadine is spreading more rapidly among avian influenza viruses of H5N1 subtype in Southeast Asia than in North America, according to the study done by investigators at St. Jude Children's Research Hospital.

12 Sep 2005

Clioquinol appears to block the genetic action of Huntington's disease

Clioquinol, an antibiotic that was banned for internal use in the United States in 1971 but is still used in topical applications, appears to block the genetic action of Huntington's disease in mice and in cell culture, according to a study reported by San Francisco VA Medical Center (SFVAMC) researchers.

12 Sep 2005

Key cellular switch that controls glucose production in liver cells

In many patients with type 2 diabetes, the liver acts like a sugar factory on overtime, churning out glucose throughout the day, even when blood sugar levels are high. Scientists at the Salk Institute for Biological Studies discovered a key cellular switch that controls glucose production in liver cells.

12 Sep 2005

Unexpected link between the viruses that cause feline and human AIDS

A University of Florida researcher has discovered an unexpected link between the viruses that cause feline and human AIDS: Cats vaccinated with an experimental strain of the human AIDS virus appear to be at least as well-protected against the feline version of the disease as those immunized with the vaccine currently used by veterinarians.

10 Sep 2005

Why do estrogen-dependent breast-cancer cells grow and spread rapidly?

Researchers at the University of Illinois at Urbana-Champaign say it may be because estrogen virtually eliminates levels of a vitally important regulatory protein.

10 Sep 2005

Scientists characterize the most infectious prion protein particles

A new study of prions - apparently malformed proteins that initiate deadly brain diseases such as Creutzfeldt-Jakob disease in humans - has yielded surprising information about how the size of prions relates to their infectivity.

10 Sep 2005

Diabetics with fatty livers could benefit from diet rich in soy protein

According to a group of researchers from Mexico they have discovered that a diet rich in soy protein may alleviate fatty liver, a disease which often accompanies diabetes.

10 Sep 2005

Depression may hasten the progression of heart disease

In a study of 32 people with heart failure, the 14 patients who felt the most depressed had nearly twice the levels of this protein in their blood.

7 Sep 2005

Stressgen granted new U.S. patent for treatment of Hepatitis B

Stressgen Biotechnologies announced today that the U.S. Patent and Trademark Office granted Patent Number 6,921,534 covering fusion protein compositions comprised of a hepatitis B virus (HBV) antigen fused to a heat shock protein (Hsp), as well as DNA encoding such fusion proteins, and methods of treating an HBV infection using these fusion proteins.

7 Sep 2005

New study dispels role of B vitamins in preventing heart attacks

According to the findings of a new study, by giving B vitamins to heart attack survivors their risk of having another attack is not reduced, and it may in fact do more harm than good.

6 Sep 2005

Researchers uncover how the inhaled form of anthrax disarms bacteria-fighting white blood cells before they can fend off the disease

The lethal toxin in anthrax paralyzes neutrophils, the white blood cells that act as the body's first defense against infection, by impairing how they build tiny filaments that allow them to crawl throughout the body and eat invading bacteria.

6 Sep 2005

Diet rich in soy protein may alleviate fatty liver

A group of researchers from Mexico has discovered that a diet rich in soy protein may alleviate fatty liver, a disease which often accompanies diabetes. The details of their findings appear in the September issue of the Journal of Lipid Research, an American Society for Biochemistry and Molecular Biology journal.

6 Sep 2005

Osteopontin protein found to be more common in patients with lung fibrosis

Idiopathic pulmonary fibrosis (IPF) is a scarring disease without a cure, irreparably damaging the ability of the tissue to transfer oxygen into the bloodstream.

6 Sep 2005

Strong social gradient in the metabolic syndrome

It is well documented that individuals with higher social status have lower risk of coronary heart disease (CHD). This is generally not explained by differences in lifestyle factors such as smoking and lack of exercise.

6 Sep 2005

Phase II clinical study of ularitide

The European Society of Cardiology (ESC) today highlighted results of a Phase II clinical study of ularitide, a synthetic form of a natriuretic peptide synthesized in the kidney for patients with acute decompensated congestive heart failure (ADHF).

5 Sep 2005

New vaccine with the potential to protect against fungal pathogens

A group of scientists in Italy have developed a vaccine with the potential to protect against fungal pathogens that commonly infect humans, according to a study by Torosantucci and colleagues in the September 5 issue of The Journal of Experimental Medicine.

5 Sep 2005

Genome of mammals is much more complex than previously thought

More than 100 scientists from Australia, Asia, Europe and the US have been probing the genome of the mouse in a joint study lasting several years.

5 Sep 2005

New findings suggest balancing Chk1 activity will produce less toxic cancer drugs

A study published by The Burnham Institute in the September edition of Molecular Cell reports that a cell-cycle checkpoint protein, known to be activated by an important class of anticancer drugs, may play crucial roles in both the hampering of therapeutic actions and aiding cancer cells to "recover" and start dividing again after treatment with these drugs.

5 Sep 2005

New understanding of how our genome works to produce a complex organism like a human being

A series of discoveries by an international consortium of scientists, including a team from The University of Queensland's Institute for Molecular Bioscience (IMB), will transform our understanding of how our genome works to produce a complex organism like a human being.

4 Sep 2005