Biochemistry News and Research

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Researchers identify rare SRC-1 gene variants related to human obesity

Maintaining a healthy body weight is no simple matter. A better understanding of how the body regulates appetite could help tip the scale toward the healthy side.

12 Apr 2019

MUSC researchers find why some babies are born with malformed hearts

Almost one percent of all American babies are born with malformed hearts. Heart abnormalities are at once the most common and most deadly type of birth defect in the U.S.

11 Apr 2019

Bruker announces innovative UHF magnet technology for high-resolution NMR in structural biology

At the 60th Experimental Nuclear Magnetic Resonance Conference (ENC, www.enc-conference.org ), Bruker announced today a breakthrough in ultra-high field high-resolution NMR spectroscopy applied to structural biology and the study of functional intrinsically disordered proteins.

From Bruker BioSpin Group 10 Apr 2019

Over-the-counter teeth whitening strips damage teeth and gums, warn experts

Three new studies have shown that hydrogen peroxide, which is commonly found in teeth whitening products, can damage dentin within tooth enamel.

10 Apr 2019

New resource accelerates use of FISH techniques to study spatial organization of DNA in cells

Researchers at Karolinska Institutet present a publicly available resource that can accelerate the use of so-called FISH techniques for studying how the genome is spatially organised in the cell nucleus.

9 Apr 2019

High Throughput Nucleic Acid Purification Simplified

Labs demand purity and flexibility for high throughput nucleic acid purification, while needing to complete difficult downstream analysis, for example NGS.

From Promega Corporation 9 Apr 2019

Study compares library preparation and sequencing platforms for single-cell RNA-sequencing

Researchers from University of Southern Denmark, Wellcome Sanger Institute and BGI, today published a study in the journal Genome Biology comparing the library preparation and sequencing platforms for single-cell RNA-sequencing.

9 Apr 2019

A gene regulatory multi-tool plays key role in unjamming the genome after DNA damage

A protein complex that is involved in nearly every step in the regulatory control of gene expression in cells has now been shown also to play a key role in clearing potential traffic jams in the production of RNA.

5 Apr 2019

Dietary fiber could help prevent chronic obstructive pulmonary disease

Dietary fiber may be a new tool in the prevention of progressive lung disease, thanks to the production of anti-inflammatory short chain fatty acids, according to a new study by Australia's Priority Research Centre for Healthy Lungs at University of Newcastle, and the Centre for Inflammation, a partnership between The University of Technology Sydney and Centenary Institute.

5 Apr 2019

GC-MS/MS of dried urine is a ‘good surrogate’ for serum testing of hormones

Researchers have shown that analyzing dried urine extracts with GC-MS/MS to assess levels of reproductive hormones in pre-and post-menopausal women provides similar results to radioimmunoassays using serum samples.

5 Apr 2019

Scientists solve mystery of how bacterial nanowires conduct electricity

Scientists have made a surprising discovery about how strange bacteria that live in soil and sediment can conduct electricity.

5 Apr 2019

Scientists use a promiscuous inhibitor to uncover cancer drug targets

Scientists at Harvard Medical School and the Dana-Farber Cancer Institute have developed a method that exploits the multitargeted nature of a chemical inhibitor to pinpoint vulnerabilities within cancer cells.

5 Apr 2019

PET images of microglial activation levels could better predict Alzheimer's disease progression

Researchers have discovered a way to better predict progression of Alzheimer's disease. By imaging microglial activation levels with positron emission tomography, researchers were able to better predict progression of the disease than with beta-amyloid PET imaging, according to a study published in the April issue of the Journal of Nuclear Medicine.

4 Apr 2019

New computational model of human kinase may provide insights for cancer drug development

Researchers have developed a computational model for human MEK1, a protein with potential as a drug target for a variety of human cancers.

4 Apr 2019

NIAID awards $22 million grant to develop antibody-based therapies against lethal viruses

The National Institute of Allergy and Infectious Diseases has awarded an international consortium led by Albert Einstein College of Medicine, part of Montefiore, a five-year, $22 million grant to develop antibody-based therapies against four highly lethal viruses for which there are no approved vaccines or treatments.

4 Apr 2019

Novel strategy to ameliorate symptoms of mitochondrial disease

Diseases affecting mitochondria, the powerhouses of our cells, are often caused by mutations in the mitochondrial DNA. Symptoms of such mitochondrial diseases in mice can be ameliorated by increasing their levels of mitochondrial DNA, according to a study by researchers at Karolinska Institutet.

3 Apr 2019

Compounds derived from common hop plant thwart cancer cells

The plant that adds flavor, color and bitterness to beer also produces a primary compound that thwarts cancer cells, and two important derivatives of the compound do as well, new research at Oregon State University shows.

3 Apr 2019

New mouse model for Joubert Syndrome developed

A new mouse model for Joubert Syndrome has been developed by University of Bath scientists, who hope it will accelerate research to understand how the disease develops as well as help develop and evaluate therapeutic approaches.

3 Apr 2019

Bruker’s timsTOF Pro mass spectrometer receives EuPA technology award at Proteomic Forum 2019

Bruker announces that on Wednesday, March 27th, its ultra-high sensitivity, high-throughput 4D proteomics platform, the timsTOF Pro mass spectrometer received the prestigious technology award during the Proteomic Forum 2019/XIII.

From Bruker Daltonics 3 Apr 2019

Study reveals new strategy to combat antibiotic resistance

A new strategy to combat antibiotic resistance has emerged from a study led by researchers at Baylor College of Medicine. Published in the journal Molecular Cell, the report reveals for the first time how bacteria evolve mutations that confer antibiotic resistance and that this process can be inhibited with FDA-approved drug edaravone.

2 Apr 2019

Biochemistry News and Research

Researchers identify rare SRC-1 gene variants related to human obesity

MUSC researchers find why some babies are born with malformed hearts

Bruker announces innovative UHF magnet technology for high-resolution NMR in structural biology

Over-the-counter teeth whitening strips damage teeth and gums, warn experts

New resource accelerates use of FISH techniques to study spatial organization of DNA in cells

High Throughput Nucleic Acid Purification Simplified

Study compares library preparation and sequencing platforms for single-cell RNA-sequencing

A gene regulatory multi-tool plays key role in unjamming the genome after DNA damage

Dietary fiber could help prevent chronic obstructive pulmonary disease

GC-MS/MS of dried urine is a ‘good surrogate’ for serum testing of hormones

Scientists solve mystery of how bacterial nanowires conduct electricity

Scientists use a promiscuous inhibitor to uncover cancer drug targets

PET images of microglial activation levels could better predict Alzheimer's disease progression

New computational model of human kinase may provide insights for cancer drug development

NIAID awards $22 million grant to develop antibody-based therapies against lethal viruses

Novel strategy to ameliorate symptoms of mitochondrial disease

Compounds derived from common hop plant thwart cancer cells

New mouse model for Joubert Syndrome developed

Bruker’s timsTOF Pro mass spectrometer receives EuPA technology award at Proteomic Forum 2019

Study reveals new strategy to combat antibiotic resistance

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