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Memory loss symptoms not sufficient to diagnose other forms of Alzheimer's

Relying on clinical symptoms of memory loss to diagnose Alzheimer's disease may miss other forms of dementia caused by Alzheimer's that don't initially affect memory, reports a new Northwestern Medicine study.

13 Sep 2016

Inhibition of RANK signaling pathway could be potential new therapy in breast cancer

Researchers at the Institute of Biomedical Research of Bellvitge, led by Dr. Eva Gonzalez-Suarez, have shown that pharmacological and genetic inhibition of signaling pathway RANK / RANKL leads to a significant reduction in recurrences and metastases in breast cancer in a mouse animal model.

13 Sep 2016

TSRI, IAVI scientists reveal new reductionist vaccine strategy to fight against HIV

A series of new studies led by scientists at The Scripps Research Institute and the International AIDS Vaccine Initiative describe a potential vaccination strategy to jump-start the selection and evolution of broadly effective antibodies to prevent HIV infection.

13 Sep 2016

Novel DNA-altering method could lead to more treatment options for diseases

Researchers in Singapore have developed a new protein that can alter DNA in living cells with much higher precision than current methods.

13 Sep 2016

Gut microbiota may play role in influencing food allergies

Countless microorganisms live in the intestinal tract. Researchers at the Technical University of Munich (TUM) have been able to demonstrate that intestinal bacteria also play a role in determining the strength of anaphylactic reactions to food allergens.

13 Sep 2016

NUS study reveals RNA editing events play vital role in gastric cancer development

A team of researchers from the Cancer Science Institute of Singapore at the National University of Singapore has found that changes in ribonucleic acid (RNA) sequences play a major role in the development of gastric cancer.

13 Sep 2016

International researchers discover 44 novel gene sites linked to hypertension

In papers receiving advance online publication in Nature Genetics, two international multi-institutional research teams describe identifying a total of 44 novel gene sites associated with hypertension or high blood pressure.

13 Sep 2016

Combinational analysis of FISH and IHC detects NSCLC patients with rare ALK fusions

The combined use of fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC) identified non-small cell lung cancer (NSCLC) patients with rare or novel anaplastic lymphoma kinase (ALK) gene rearrangements, not otherwise identified by FISH alone, that showed response to crizotinib treatment.

12 Sep 2016

Cone snail venom could hold key to efficient therapies for diabetes

New research has found that venom extracted from a species of marine cone snail could hold the key to developing 'ultra-fast-acting' insulins, leading to more efficient therapies for diabetes management.

12 Sep 2016

First accurate simulation reveals how virus shape changes when invading host cell

For the first time, scientists know what happens to a virus' shape when it invades a host cell, thanks to an experiment by researchers at Penn State College of Medicine and University of Pittsburgh School of Medicine.

12 Sep 2016

Study reveals promising strategy against bladder cancer metastasis

The popular kids' card game "Exploding Kittens" teaches a concept critical to cancer science: When a player plays a "Nope" card, the subsequent player may lay another "Nope", thus creating a double-negative that becomes a positive, allowing the initial action to proceed.

12 Sep 2016

Experts develop urine-based method to diagnose conditions in newborn babies

Experts from the V. I. Kulakov Research Center for Obstetrics, Gynecology and Perinatology and the Moscow Institute of Physics and Technology have devised a method that uses the urinary proteome to diagnose conditions in newborn babies.

9 Sep 2016

Study opens door to new class of therapies for Ras-dependent cancers

New research from The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai identifies a protein that may be an unexplored target to develop new cancer therapies.

9 Sep 2016

Research offers new insights into underlying mechanisms of deadly cystic fibrosis

A minor hiccup in the sequence of a human gene can have devastating impacts on health. Such flaws cause cystic fibrosis (CF), a disease affecting the lungs and other vital organs, often leading to death by the age of 30.

9 Sep 2016

New treatment reduces activity of Huntington's disease gene for several months in mice

A single injection of a new treatment has reduced the activity of the gene responsible for Huntington's disease for several months in a trial in mice.

9 Sep 2016

CHORI scientists reveal improved protective antibody responses to new meningococcal vaccine

A study conducted by UCSF Benioff Children's Hospital Oakland Research Institute scientists shows greatly improved protective antibody responses to a new mutant vaccine antigen for prevention of disease caused by Neisseria meningitidis - also known as meningococcus - that has the potential to improve the current vaccines for meningitis.

9 Sep 2016

Heat shock proteins may play role in triggering Schistosoma invasion

A protein known for helping cells withstand stress may also act as a switch that triggers free-swimming Schistosoma larvae to begin penetrating the skin and transforming into the parasitic flatworms that burden more than 240 million people worldwide with schistosomiasis.

9 Sep 2016

Triptolide molecule can turn into 'cruise missile' against cancer

More than 20 years ago, a billboard in China piqued the interest of a chemical biologist. It endorsed an extract from the plant known as the “thunder god vine” as an immunosuppressant.

9 Sep 2016

Scientists reveal new structural insights on key protein from mosquitoes linked to spread of Zika

As health departments around the U.S. boost efforts to combat Zika, scientists are working on new ways to kill the mosquitoes that carry the virus. One approach involves understanding the molecular mechanisms that keep the bugs alive so we can then undermine them.

9 Sep 2016

Novel approach may help combat kidney disease in diabetic patients

A new strategy may help halt the progression of kidney disease in patients with diabetes.

9 Sep 2016

G Protein News and Research

Memory loss symptoms not sufficient to diagnose other forms of Alzheimer's

Inhibition of RANK signaling pathway could be potential new therapy in breast cancer

TSRI, IAVI scientists reveal new reductionist vaccine strategy to fight against HIV

Novel DNA-altering method could lead to more treatment options for diseases

Gut microbiota may play role in influencing food allergies

NUS study reveals RNA editing events play vital role in gastric cancer development

International researchers discover 44 novel gene sites linked to hypertension

Combinational analysis of FISH and IHC detects NSCLC patients with rare ALK fusions

Cone snail venom could hold key to efficient therapies for diabetes

First accurate simulation reveals how virus shape changes when invading host cell

Study reveals promising strategy against bladder cancer metastasis

Experts develop urine-based method to diagnose conditions in newborn babies

Study opens door to new class of therapies for Ras-dependent cancers

Research offers new insights into underlying mechanisms of deadly cystic fibrosis

New treatment reduces activity of Huntington's disease gene for several months in mice

CHORI scientists reveal improved protective antibody responses to new meningococcal vaccine

Heat shock proteins may play role in triggering Schistosoma invasion

Triptolide molecule can turn into 'cruise missile' against cancer

Scientists reveal new structural insights on key protein from mosquitoes linked to spread of Zika

Novel approach may help combat kidney disease in diabetic patients

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