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Researchers modify software to predict gene transcription

A modification to an "ace" gene prediction program by computer scientists at Washington University in St. Louis now enables scientists to predict the very beginnings of gene transcription start sites and where the first splice occurs thereby defining the first exon of the gene.

13 Jul 2005

If strawberries weren't red they wouldn't cause allergies

Researchers say if strawberries were another colour they might be safer for allergy sufferers to eat.

12 Jul 2005

Serotonin may play a role in maintaining circadian rhythm

Researchers at the University of Pennsylvania School of Medicine have determined how serotonin decreases the body's sensitivity to light and that exposure to constant darkness leads to a decrease in serotonin levels in the brain of fruit flies.

12 Jul 2005

Curcumin has potent anticancer powers

Curcumin, a spice commonly used in curries and other south Asian cooking, blocks a key biological pathway needed for development of melanoma and other cancers, say researchers from the University of Texas M. D. Anderson Cancer Center.

12 Jul 2005

Researchers have pinpointed specific gene and protein over-production in metastatic melanoma

Gene amplification is a process that often happens in cancer cells when the normal DNA replication process is altered, causing many copies of the gene to be produced instead of a single copy of a region of a chromosome.

12 Jul 2005

X-ray crystallography images show how a protein called alpha-actinin performs molecular ballet

As a cell moves forward, physical stress on its skeleton triggers molecular fingers and arms to grasp each other in reinforcing links that stabilize the skeleton, according to images produced by investigators at St. Jude Children's Research Hospital.

12 Jul 2005

Discovery of protein deficit that causes drug toxicity

Mayo Clinic researchers have discovered an inherited structural mechanism that can make drugs for some diseases toxic for some patients.

11 Jul 2005

Keap1 protein - a promising new target for drugs to fight many different kinds of cancer

Researchers at the University of Illinois at Chicago are unraveling the biochemical mechanism by which functional foods combat cancer.

11 Jul 2005

New understanding of degeneration of brain cells in patients with Alzheimer's, Huntington's, and Parkinson's diseases

A ground-breaking new research approach to understanding the cellular processes of Alzheimer's and other degenerative diseases has revealed a promising pathway to the development of new types of drugs for these diseases.

11 Jul 2005

Researchers have discovered how p16 gene works

University of Minnesota researchers have discovered how a gene that suppresses the development of melanoma and other human cancers works. The study points the way to treatments based on the function of the gene.

11 Jul 2005

Lack of a blood clotting protein may protect against clogged arteries

Reporting in the July 18 issue of The Journal of Experimental Medicine, a group of scientists in Wurzburg, Germany show that the lack of a blood clotting protein may protect against clogged arteries with no risk of excessive bleeding.

11 Jul 2005

New roles for granulocyte colony-stimulating factor (G-CSF) in treating stroke

In a study appearing online on July 7 in advance of print publication of the August 1 issue of the Journal of Clinical Investigation, Armin Schneider and colleagues from Axaron Biosciences describe new roles for granulocyte colony-stimulating factor (G-CSF) in treating stroke and other central nervous system roles of this protein.

11 Jul 2005

Scientists discover how an HIV protein fragment shuts down an immune response

The HIV virus hides out in the very immune system cells that are meant to protect the body from viral infection. But how does it prevent these cells from mounting a full-scale attack against the invader?

11 Jul 2005

New approach to preventing or reversing heart failure

Duke University Medical Center researchers have identified a new protein that plays a critical role in enabling the heart to respond to such external stimuli as exercise or stress, as well as in the progressive loss of heart function that is heart failure, the researchers said.

11 Jul 2005

Blood pressure enzyme linked to SARS virus, could help fight diseases that cause lung failure

Researchers in Austria say that an enzyme that regulates blood pressure is also involved in the SARS virus, and the discovery could lead to new ways of treating diseases that cause lung failure.

11 Jul 2005

Researchers clarifiy role of Notch protein in T-cell development

Researchers at the University of Pennsylvania School of Medicine have recently clarified the role of the Notch protein in T-cell development. T cells are required for many aspects of immunity, including fighting viral infections, providing cancer surveillance, and regulating multiple aspects of the immune response.

6 Jul 2005

Researchers have discovered a key regulatory molecule for Huntington's disease

Researchers have discovered a key regulatory molecule whose overactivation by the abnormal protein produced in Huntington's disease (HD) causes the central pathologies of the disease.

6 Jul 2005

Point-of-selection nutrition information cards can spur students to pick the right foods

Mystery meat not withstanding, high school cafeterias can provide nutritional, balanced and healthful meals, but students have to choose correctly.

6 Jul 2005

Cancer cells may be able to avoid destruction by anti-vascular and anti-angiogenesis agents

Cancer cells may be able to avoid destruction by anti-vascular and anti-angiogenesis agents through a cellular stress response that activates a pro-survival protein called GRP78, according to researchers from the Keck School of Medicine of the University of Southern California.

6 Jul 2005

HIF-1alpha expression regulates the bactericidal capacity of phagocytes

When microorganisms invade the body, immune mechanisms kick in to fight them off. The infected tissues typically show depleted oxygen levels, and a protein called HIF-1 alpha regulates this. Interestingly, the cells responsible for destroying the foreign pathogens are effective in this low-oxygen environment.

6 Jul 2005

G Protein News and Research

Researchers modify software to predict gene transcription

If strawberries weren't red they wouldn't cause allergies

Serotonin may play a role in maintaining circadian rhythm

Curcumin has potent anticancer powers

Researchers have pinpointed specific gene and protein over-production in metastatic melanoma

X-ray crystallography images show how a protein called alpha-actinin performs molecular ballet

Discovery of protein deficit that causes drug toxicity

Keap1 protein - a promising new target for drugs to fight many different kinds of cancer

New understanding of degeneration of brain cells in patients with Alzheimer's, Huntington's, and Parkinson's diseases

Researchers have discovered how p16 gene works

Lack of a blood clotting protein may protect against clogged arteries

New roles for granulocyte colony-stimulating factor (G-CSF) in treating stroke

Scientists discover how an HIV protein fragment shuts down an immune response

New approach to preventing or reversing heart failure

Blood pressure enzyme linked to SARS virus, could help fight diseases that cause lung failure

Researchers clarifiy role of Notch protein in T-cell development

Researchers have discovered a key regulatory molecule for Huntington's disease

Point-of-selection nutrition information cards can spur students to pick the right foods

Cancer cells may be able to avoid destruction by anti-vascular and anti-angiogenesis agents

HIF-1alpha expression regulates the bactericidal capacity of phagocytes

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