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Scientist shows how immune system 'attacks' liver cells during hepatitis by using JunB gene

Viral infections are the primary cause of liver inflammation or hepatitis, affecting hundreds of millions of people all over the world, and they represent a public health problem worldwide.

10 Nov 2013

Olympus hosts fourth annual neuroimaging symposium on functional brain imaging with cellular resolution

Olympus is hosting its fourth annual neuroimaging symposium in conjunction with the 2013 meeting of the Society for Neuroscience (SfN) on Monday, November 11 in San Diego. The Olympus Neuroimaging Symposium will be held near the Convention Center at the San Diego Marriott Marquis and Marina, San Diego Ballroom – Salon A, beginning at 6:30pm. The symposium and reception are open to all media and SfN registered attendees.

From Evident Corporation - Life Sciences 8 Nov 2013

Breast cancer drug appears to protect cells against UV radiation, inflammation

Exemestane, a synthetic steroid drug widely prescribed to fight breast cancers that thrive on estrogens, not only inhibits the production of the hormone, but also appears to protect cells throughout the body against damage induced by UV radiation, inflammation and other assaults, according to results of research by Johns Hopkins scientists.

8 Nov 2013

Drug formulation services for highly potent active pharmaceutical ingredients provided by Evonik

Evonik Industries has broadened its capabilities in finished drug product formulation and clinical supply manufacturing and can now handle drug products containing highly potent active pharmaceutical ingredients (HPAPIs) in Darmstadt, Germany, and Birmingham, Alabama/USA. Investments in high containment facilities and upgrades in the laboratory and GMP areas in Birmingham enable Evonik to handle HPAPIs with occupational exposure limits (OEL) as low as 0.1μg/m3 and in Darmstadt as low as 1 μg/m3. Starting 2014, OEL as low as 0.1μg/m3 will also be possible in Darmstadt.

8 Nov 2013

Gladstone-led study sheds light on critical molecular process

One of biology's most fundamental processes is something called transcription. It is just one step of many required to build proteins-and without it life would not exist. However, many aspects of transcription remain shrouded in mystery. But now, scientists at the Gladstone Institutes are shedding light on key aspects of transcription, and in so doing are coming even closer to understanding the importance of this process in the growth and development of cells-as well as what happens when this process goes awry.

8 Nov 2013

Clinical testing expanded for vaccine against latent TB

Statens Serum Institut and Aeras today announced the initiation of a Phase I/IIa clinical trial for a candidate tuberculosis vaccine designed to protect people, especially those latently infected with TB, from developing active TB disease.

8 Nov 2013

Findings raise prospects for new therapies to protect heart from progressive disease

Some of the most commonly prescribed drugs for the treatment of heart failure are beta-blockers and nitrates, which help to relax blood vessels and decrease the heart's workload. The drugs were thought to produce those effects through distinct molecular pathways, but according to a new study led by scientists at Temple University School of Medicine, both types of drugs may help the failing heart by counteracting the effects of an enzyme known as GRK2.

8 Nov 2013

Researchers identify chain reaction that triggers regrowth of some damaged nerve cell

Researchers at Washington University School of Medicine in St. Louis have identified a chain reaction that triggers the regrowth of some damaged nerve cell branches, a discovery that one day may help improve treatments for nerve injuries that can cause loss of sensation or paralysis.

8 Nov 2013

Scientists to develop on-demand drug-delivery system for pain management in osteoarthritis patients

Scientists are reporting development of a squishy gel that when compressed - like at a painful knee joint - releases anti-inflammatory medicine. The new material could someday deliver medications when and where osteoarthritis patients need it most. Their study appears in the ACS journal Biomacromolecules.

8 Nov 2013

SIgN scientist wins prestigious EMBO Young Investigator 2013 award

Dr Florent Ginhoux, Principal Investigator at the Singapore Immunology Network, has been awarded the prestigious EMBO Young Investigator 2013 award. The European Molecular Biology Organization Young Investigator Programme recognises young, promising researchers who are less than forty years of age and who have established their first laboratories in Europe and EMBO cooperation partner countries in the past four years.

7 Nov 2013

Researchers identify new class of anti-inflammatory drugs may be used to treat IBD

Researchers in UCD Conway Institute and Systems Biology Ireland have identified a way that a new class of anti-inflammatory drugs may be used to treat inflammatory bowel disease (IBD).

7 Nov 2013

Diagnostic technology advancing but barriers prevent integration into care, IDSA report warns

Despite advances in diagnostic technology, there is an urgent need for tests that are easy to use, identify the bug causing an infection and provide results faster than current tests, according to a report from the Infectious Diseases Society of America published today in a special supplement to Clinical Infectious Diseases.

7 Nov 2013

Investigators find potential new target for treatment of low-grade gliomas

Investigators at Johns Hopkins have found a known genetic pathway to be active in many difficult-to-treat pediatric brain tumors called low-grade gliomas, potentially offering a new target for the treatment of these cancers.

7 Nov 2013

University of Adelaide research uses special adult stem cells to treat Hurler's syndrome

University of Adelaide research using special adult stem cells is promising new hope for better treatments for the devastating genetic disease Hurler's syndrome.

7 Nov 2013

Cocaine addicts may become trapped in drug binges due to emotional lows, says study

Cocaine addicts may become trapped in drug binges - not because of the euphoric highs they are chasing but rather the unbearable emotional lows they desperately want to avoid.

7 Nov 2013

Tea helps promote weight loss and improve bone health

Decades worth of research shows that tea-the second most consumed beverage in the world-may help prevent chronic illnesses, including heart disease, certain types of cancer and type 2 diabetes. New research shows tea has been found to help promote weight loss and maintain a healthy weight, improve bone health and activate areas of the brain that bolster attention, problem solving and mood.

7 Nov 2013

MU researchers find more accurate laboratory method for diagnosing pancreatic cancer

Researchers from the University of Missouri have found a more accurate laboratory method for diagnosing pancreatic cancer, the fourth leading cause of cancer death in the United States. The disease causes more than 38,000 deaths each year in the United States, and kills 94 percent of people with the illness within five years, according to the National Cancer Institute.

7 Nov 2013

Atherotech Diagnostics Lab announces opening of patient service center in Sarasota, FL

Atherotech Diagnostics Lab, a leading clinical reference laboratory specializing in cardiometabolic testing and disease management solutions, today announced the opening of its patient service center in Sarasota, Fla. A physician open house on Wednesday, November 6, 2013, from 5:00 p.m. until 8:00 p.m. at 4014 Sawyer Road in Sarasota, Fla., celebrates the opening of the center.

6 Nov 2013

New 4th generation HIV assays now available to improve screening for HIV infection

Laboratory Corporation of America Holdings announced today the availability of a 4th generation HIV antigen/antibody combination assay and a new diagnostic algorithm that improves screening for HIV infection.

6 Nov 2013

New drug combination therapy effectively kills cancer cells

Results from a recent preclinical study have shown that a new drug combination therapy being developed at Virginia Commonwealth University Massey Cancer Center effectively killed colon, liver, lung, kidney, breast and brain cancer cells while having little effect on noncancerous cells. The results lay the foundation for researchers to plan a future phase 1 clinical trial to test the safety of the therapy in a small group of patients.

6 Nov 2013

Laboratory News and Research

Scientist shows how immune system 'attacks' liver cells during hepatitis by using JunB gene

Olympus hosts fourth annual neuroimaging symposium on functional brain imaging with cellular resolution

Breast cancer drug appears to protect cells against UV radiation, inflammation

Drug formulation services for highly potent active pharmaceutical ingredients provided by Evonik

Gladstone-led study sheds light on critical molecular process

Clinical testing expanded for vaccine against latent TB

Findings raise prospects for new therapies to protect heart from progressive disease

Researchers identify chain reaction that triggers regrowth of some damaged nerve cell

Scientists to develop on-demand drug-delivery system for pain management in osteoarthritis patients

SIgN scientist wins prestigious EMBO Young Investigator 2013 award

Researchers identify new class of anti-inflammatory drugs may be used to treat IBD

Diagnostic technology advancing but barriers prevent integration into care, IDSA report warns

Investigators find potential new target for treatment of low-grade gliomas

University of Adelaide research uses special adult stem cells to treat Hurler's syndrome

Cocaine addicts may become trapped in drug binges due to emotional lows, says study

Tea helps promote weight loss and improve bone health

MU researchers find more accurate laboratory method for diagnosing pancreatic cancer

Atherotech Diagnostics Lab announces opening of patient service center in Sarasota, FL

New 4th generation HIV assays now available to improve screening for HIV infection

New drug combination therapy effectively kills cancer cells

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