Research News and Research

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RPL26 and nucleolin play critical roles in controlling the production of p53

Investigators at St. Jude Children's Research Hospital have discovered a previously unrecognized mechanism that controls a key protein linked to the cell's response to stress - a finding that holds promise for new ways to enhance cancer therapies or protect cells from dying after exposure to damaging chemicals or radiation.

9 Oct 2005

Scientists genetically modify male mosquitoes to express a glowing protein in their gonads - may help control the mosquito population

By providing a way to quickly sex mosquitoes, the advance paves the way for pooling large numbers of sterile males which could be used to control the mosquito population.

9 Oct 2005

New data demonstrates how CA4P has anti-tumor and anti-angiogenic activity

Anti-angiogenic agents have been successful in the clinic for blocking the growth of solid tumors. However, these agents used in combination with chemotherapy have improved the survival of patients with cancers by only several months.

9 Oct 2005

Gut antibody could prove to be a promising drug target for Crohn's disease

A collaboration led by the Burnham Institute for Medical Research has found that an antibody which binds to an unusual sugar molecule residing in the gut halts the inflammation seen in Crohn's disease and other intestinal inflammations. The antibody could prove to be a promising drug target for these common chronic intestinal disorders.

9 Oct 2005

Tissue engineering used to reconstruct defective tracheas (windpipes) in fetal lambs

Researchers at Children's Hospital Boston report using tissue engineering to reconstruct defective tracheas (windpipes) in fetal lambs, first using cells from the amniotic fluid to grow sections of cartilage tube, and then implanting these living grafts into the lambs while still in the womb.

9 Oct 2005

New information regarding the genetic, cellular and neurological bases of susceptibility to autism and schizophrenia

Two New Jersey research teams are reporting discoveries about the biological nature of psychiatric disorders that may bring them closer to the ultimate goal of finding cures for complex diseases, such as autism and schizophrenia.

9 Oct 2005

Avian influenza and the U.S

If a virulent strain of avian influenza ever struck the U.S. poultry industry, this country probably would fare better than many other nations due to careful biosecurity procedures in force.

9 Oct 2005

Novel methodology that can be used to investigate choice and introspection

When evaluating facial attractiveness, participants may fail to notice a radical change to the outcome of their choice, according to a study by researchers at Lund University, Sweden, and New York University. Equally surprising, the study shows that participants may produce confabulatory reports when asked to describe the reasons behind their choices.

9 Oct 2005

Minimally invasive needle breast biopsies and sentinel node biopsies should be performed more routinely than they currently are

Physicians should strive to replace traditional, invasive procedures for diagnosing breast cancer with proven, less-invasive diagnostic methods, according to an international panel of breast cancer experts convened at the Keck School of Medicine of the University of Southern California.

9 Oct 2005

New role for the blood protein serum amyloid P in the body's response to medical materials

Using a technique called proteomics, the researchers identified many of the blood proteins that stick (adsorb) to the surfaces of medical devices. Blood proteins that adsorb to the surfaces of materials unfold and can be recognized by the body, which then mounts a response against the device.

5 Oct 2005

Deadly 1918 Spanish flue virus has been reconstructed and characterized

This research, reported in this week's issue of Science, is part of a larger research initiative being led by Adolfo Garcia-Sastre, PhD, Professor of Microbiology and Peter Palese, PhD, Professor and Chairman of Microbiology at Mount Sinai School of Medicine.

5 Oct 2005

Fruits and vegetables can increase or decrease the activity and toxicity of orally-administered drugs

Eating fruits and vegetables is essential to living a long and healthy life, yet research has shown they can cause dangerous interactions with medicines.

5 Oct 2005

Cells inside the hair follicle are true multipotent stem cells

Using an animal model, a research team led by Yann Barrandon at the EPFL (Ecole Polytechnique Federale de Lausanne) and the CHUV (Lausanne University Hospital) has discovered that certain cells inside the hair follicle are true multipotent stem cells, capable of developing into the many different cell types needed for hair growth and follicle replacement.

5 Oct 2005

The cocktail party problem

Known as "the cocktail party problem," the ability of the brain's auditory processing centers to sort a babble of different sounds, like cocktail party chatter, into identifiable individual voices has long been a mystery.

5 Oct 2005

Most comprehensive picture to date of how influenza viruses evolve and are transmitted

In the first large-scale effort of its kind, researchers have determined the full genetic sequence of more than 200 distinct strains of human influenza virus.

5 Oct 2005

Earliest signs of Alzheimer's can be screened for with an electroencephalograph

Although Alzheimer's disease affects millions of people worldwide, there is no way to identify this devastating brain disease at its earliest stages when there still may be time to delay or even prevent the downward spiral into dementia.

5 Oct 2005

Richness of motor training determines not only what we learn but how we learn

Practice makes perfect when people learn behaviors, from baseball pitching to chess playing to public speaking. Biomedical engineers at Washington University in St. Louis have now identified how people use individual experiences to improve performance.

5 Oct 2005

Study looks at childrens end-of-life care preferences

Pediatric cancer patients as young as 10 years old who are aware that their disease is incurable have the ability to participate meaningfully in discussions of their own end-of-life care with family members and the health care team, according to investigators at St. Jude Children's Research Hospital and Sydney Children's Hospital.

5 Oct 2005

Influenza evolution in action

On the eve of the 2005-06 flu season, scientists at The Institute for Genomic Research (TIGR) have captured influenza evolution in action. In a study published in this week's journal Nature, the researchers report the first large-scale project to sequence the influenza virus.

5 Oct 2005

New set of guidelines for treating the mental health needs of incarcerated youth

Although as many as 65 to75 percent of juvenile offenders have one or more psychiatric disorders, most juvenile correctional facilities do not have the resources to serve them.

5 Oct 2005

Research News and Research

RPL26 and nucleolin play critical roles in controlling the production of p53

Scientists genetically modify male mosquitoes to express a glowing protein in their gonads - may help control the mosquito population

New data demonstrates how CA4P has anti-tumor and anti-angiogenic activity

Gut antibody could prove to be a promising drug target for Crohn's disease

Tissue engineering used to reconstruct defective tracheas (windpipes) in fetal lambs

New information regarding the genetic, cellular and neurological bases of susceptibility to autism and schizophrenia

Avian influenza and the U.S

Novel methodology that can be used to investigate choice and introspection

Minimally invasive needle breast biopsies and sentinel node biopsies should be performed more routinely than they currently are

New role for the blood protein serum amyloid P in the body's response to medical materials

Deadly 1918 Spanish flue virus has been reconstructed and characterized

Fruits and vegetables can increase or decrease the activity and toxicity of orally-administered drugs

Cells inside the hair follicle are true multipotent stem cells

The cocktail party problem

Most comprehensive picture to date of how influenza viruses evolve and are transmitted

Earliest signs of Alzheimer's can be screened for with an electroencephalograph

Richness of motor training determines not only what we learn but how we learn

Study looks at childrens end-of-life care preferences

Influenza evolution in action

New set of guidelines for treating the mental health needs of incarcerated youth

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