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Organosilicon compounds help improve lithium battery technology

With the help of new silicon-based compounds, scientists -- and patients -- are getting a significant new charge out of the tiny lithium batteries used in implantable devices to help treat nervous system and other disorders.

3 Oct 2005

First identification of the genetic basis of disease in a patient with a complex I assembly defect

Mitochondrial complex I deficiency is one of the most common defects in patients with mitochondrial disease. The deficiency results from a failure to assemble the enzyme properly, but the nature of the molecular chaperones that are necessary for this process in mammals have remained obscure.

3 Oct 2005

Microarray technology may help tailor breast cancer therapy

Microarray technology could be used to tailor therapy according to the individual, and prevent breast cancer patients from having to undergo painful unsuccessful therapies.

3 Oct 2005

Research may help create drugs to target the molecule-binding pathway, beneficial for treating arthritis and reducing inflammation

The first close-up look at a pro-inflammatory signaling molecule involved in immune response in mammals suggests that researchers "should rethink what they are doing" in creating drugs based on a fruit-fly model, scientists say.

3 Oct 2005

Concerta, a once-daily form of the drug methylphenidate, successfully controlled ADHD symptoms

A new study has found that an all-day, extended-release stimulant for treating attention-deficit hyperactivity disorder (ADHD) remains effective for up to two years without significant side effects.

3 Oct 2005

Development of aggressive forms of prostate cancer may be influenced by environmental effects that occur early in life

How heavy a man is at the time he is diagnosed with prostate cancer, as well as his history of weight gain, appear to play significant roles in how aggressive his cancer may become, say researchers at the University of Texas M. D. Anderson Cancer Center.

3 Oct 2005

Clinical trials of daily oral antiretroviral dosing as pre-exposure prophylaxis

Writing in the journal Science, an international team of researchers, clinicians and others explains that a promising, relatively new approach is for people not infected but at high risk to take drugs that might prevent them from contracting HIV. But debate over the particulars of the strategy has slowed progress.

3 Oct 2005

MRI may better enable physicians to plan care for infants with heart defects

Magnetic resonance imaging (MRI) techniques can provide real-time measurements of volume in a fetal heart, and may better enable physicians to plan care for infants with heart defects, according to a new study.

3 Oct 2005

Attitudes of a peer group are more influential than a group that is not as closely allied

According to a study at Yale, one of the most effective ways to change negative attitudes about obese people is by addressing perceptions of normative beliefs within particular social groups.

3 Oct 2005

What works in preventing and reducing juvenile delinquency?

A new report released by the University of Wisconsin-Madison and the UW-Extension synthesizes the latest research on what works in preventing and reducing juvenile delinquency.

28 Sep 2005

Grant for private, secure, electronic medical records search system

A Boston consortium has been awarded one of two national grants to form a CDC Center of Excellence in Public Health Informatics.

28 Sep 2005

Housework has an adverse effect on wages

While prior research has shown that housework has an adverse effect on wages, a new University of Michigan study finds that only young and middle-aged women are affected.

28 Sep 2005

Nicotine has an unusual psychological property that may drive dependence

Associate Professor Athina Markou, Ph.D., who is in the Scripps Research Molecular and Integrative Neurosciences Department at Scripps Research’s La Jolla Campus, and Paul Kenny, Ph.D., a former Research Associate in her laboratory, report in an upcoming issue of the journal Neuropsychopharmacology that nicotine has an unusual psychological property that may drive dependence.

28 Sep 2005

Researchers look at pharmacogenomics

When patients receive chemotherapy, 15 percent will have severe side effects while 85 percent will not - even though they're given the same relative dose.

28 Sep 2005

HeartMate XVE left ventricular assist device

Nine years ago this week, a team of University of Michigan doctors gave a dying heart patient a second chance at life by implanting a high-tech pump in his chest. The high-risk procedure was the first in Michigan performed using a new blood-pumping device called a HeartMate XVE left ventricular assist device, which helped the patient live until he received a heart transplant five weeks later.

28 Sep 2005

Fever of unknown origin might be a marker of occult cancer

Fever of unknown origin is characterised by a fever of more than 3 weeks’ duration, temperatures of more than 38.3°C and a failure to identify the origin of the fever. Underlying causes of these fevers are difficult to diagnose, but proposed causes are infections, cancers and collagen-vascular diseases.

28 Sep 2005

Alternative ways to manage chronic pain

Yoga, massage or plain old exercise? It could be just what the doctor ordered to minimize pain from chronic conditions such as rheumatoid arthritis, osteoarthritis, neck pain, low back pain or fibromyalgia, according to the September issue of Mayo Clinic Women's HealthSource.

28 Sep 2005

Nanoparticles as an invisible diet

Utah State University researchers are in the early stages of scientifically tricking the body into eating less and finding a treatment for obesity without dangerous side effects.

28 Sep 2005

Effective removal of face masks from players who sustain c-spine injuries

This fall, as more than a million high school football players take to the gridiron, University of New Hampshire's Erik Swartz is focused on the worst-case scenario.

28 Sep 2005

Salivary antimicrobial peptide expression and dental caries experience in children

A study comparing antimicrobial peptides, or AMPs, a group of small proteins that occur naturally in human saliva and act like antibiotics against oral bacteria, could lead to new ways to screen children for risk of tooth decay and protect them against this common, chronic problem.

28 Sep 2005