Research News and Research

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Low-dose aspirin might prevent the cardiovascular damage known to arise from use of the painkiller rofecoxib (Vioxx)

Their findings that a chemical imbalance might underlie such damage could also lead to the development of anti-inflammatory drugs without the adverse side effects, the researchers said.

20 Sep 2005

Research could improve clinical care, help educate women on premature birth

A March of Dimes expert panel has recommended a targeted research agenda designed improve the lives of thousands of babies by preventing premature birth. The agenda has been published in the American Journal of Obstetrics and Gynecology.

20 Sep 2005

Gaps in the intestinal barrier could be a cause of inflammatory diseases of the gut such as Crohn's Disease

Their research, led by Professor Alastair Watson in the University's Faculty of Medicine, could have important implications for the treatment of patients with diseases like Crohn's - an inflammatory bowel disorder that causes severe ulceration in the intestine, leading to pain, bleeding and diarrhoea.

20 Sep 2005

Phantom pain following spinal cord injury is the result of hypersensitive neurons in the thalamic region of brain

Yale researchers report the first evidence that phantom pain following spinal cord injury is the result of hypersensitive neurons in the thalamic region of the brain that can be suppressed with specially designed molecular agents.

20 Sep 2005

PUMA protein offers critical insights for developing new anti-cancer drugs

The discovery of how the activities of the protein p53 initiate signals that trigger cell suicide offers critical insights for developing new anti-cancer drugs, according to investigators from St. Jude Children's Research Hospital.

20 Sep 2005

Liverpool scientists have found a way of identifying families at high risk of pancreatic cancer

The team has developed a novel means of testing for pancreatic cancer that will enable doctors to treat the killer disease at its earliest stages. They are also now able to show how the risk of cancer for these patients changes with age.

20 Sep 2005

Snail, a molecule normally important in embryonic development, can promote breast cancer recurrence

Using a recently developed mouse model of breast cancer, a team from the University of Pennsylvania School of Medicine has shown that Snail, a molecule normally important in embryonic development, can promote breast cancer recurrence.

20 Sep 2005

Salicylate an active metabolite of aspirin - weakens lipid membranes

It's well known that high doses of aspirin can cause ulcers and temporary deafness, but the biochemical mechanism responsible for these phenomena has never been deciphered.

19 Sep 2005

Enhanced imaging techniques could improve medical diagnosis

Chris Wyatt is a Virginia Tech electrical engineer who is attempting to provide the medical community with better, quicker, and more relevant images of the human body. The side effects are not bad either - lower medical costs, new treatments, and earlier disease detection.

19 Sep 2005

Healthcare workers show general apathy towards the flu vaccination

Low flu vaccination rates among healthcare workers could be risking the lives of frail elderly patients and increasing winter pressures in UK hospitals, according to research published in the latest issue of Journal of Clinical Nursing.

19 Sep 2005

Public hospital patients are often denied access to Laparoscopic Adjustable Gastric Banding (LAGB) surgery

Public hospital patients are often denied access to one of the most effective forms of weight loss treatment Laparoscopic Adjustable Gastric Banding (LAGB) surgery, a Monash expert says.

19 Sep 2005

People who take risks more satisfied with their lives

Tall people are more prepared to take risks than small people, women are more careful than men, and the willingness to take risks markedly decreases with age: these are the findings arrived at by researchers from the Institute for the Study of Labor (IZA), the University of Bonn and the German Institute for Economic Research (DIW) in Berlin.

19 Sep 2005

PSA remains the best measure of the likelihood of prostate cancer recurrence after surgery

Despite recent claims by some urologists that measuring the blood protein prostate-specific antigen (PSA) may not be effective in predicting risk of prostate cancer, a Johns Hopkins study of more than 2,000 men confirms that PSA remains the best measure of the likelihood of cancer recurrence after surgery.

19 Sep 2005

Oral contraceptives appear to reduce risk of developing multiple sclerosis

Over a three-year period, the risk of developing multiple sclerosis (MS) was reduced in women taking oral contraceptives, according to a study in the September issue of Archives of Neurology.

19 Sep 2005

More than two thirds of meta-analyses available to critical care physicians have major methodological flaws

Research published in Critical Care concludes that the overall quality of meta-analyses in this field is poor, but has improved over time, possibly due to the publication of the Quality of Reporting of Meta-analyses statement (QUOROM) in 1999.

19 Sep 2005

Prions rapidly 'remodel' good protein into bad

Two Brown Medical School biologists have figured out the fate of healthy protein when it comes in contact with the infectious prion form in yeast: The protein converts to the prion form, rendering it infectious. In an instant, good protein goes bad.

19 Sep 2005

Can we reverse mental declines? Well, for most of us, the answer is yes

As we get beyond retirement age, most of us will not be as mentally sharp as we once were. But a researcher at the University of Alberta says most people have the ability to reverse the mental declines that come with aging.

19 Sep 2005

Discovery that protein CD38 interrupts an interaction between the AIDS virus and its point of entry into cells

Cornell University researchers have discovered the 3-D crystal structure of a protein, human CD38, which may lead to important discoveries about how cells release calcium - a mineral used in almost every cellular process.

19 Sep 2005

Possible new target for treating obesity and diabetes

The new target, a molecule called hVps34, is activated by amino acids (nutrients) entering the cell. This molecule triggers the activation of an enzyme, S6 Kinase 1 (S6K1), whose function UC researchers linked last year to obesity and insulin resistance.

19 Sep 2005

Injury prevention could save Maryland at least $700 million per year

In 2003, the total estimated cost of injuries in Maryland due to lost productivity and premature mortality was $1.9 billion dollars.

19 Sep 2005

Research News and Research

Low-dose aspirin might prevent the cardiovascular damage known to arise from use of the painkiller rofecoxib (Vioxx)

Research could improve clinical care, help educate women on premature birth

Gaps in the intestinal barrier could be a cause of inflammatory diseases of the gut such as Crohn's Disease

Phantom pain following spinal cord injury is the result of hypersensitive neurons in the thalamic region of brain

PUMA protein offers critical insights for developing new anti-cancer drugs

Liverpool scientists have found a way of identifying families at high risk of pancreatic cancer

Snail, a molecule normally important in embryonic development, can promote breast cancer recurrence

Salicylate an active metabolite of aspirin - weakens lipid membranes

Enhanced imaging techniques could improve medical diagnosis

Healthcare workers show general apathy towards the flu vaccination

Public hospital patients are often denied access to Laparoscopic Adjustable Gastric Banding (LAGB) surgery

People who take risks more satisfied with their lives

PSA remains the best measure of the likelihood of prostate cancer recurrence after surgery

Oral contraceptives appear to reduce risk of developing multiple sclerosis

More than two thirds of meta-analyses available to critical care physicians have major methodological flaws

Prions rapidly 'remodel' good protein into bad

Can we reverse mental declines? Well, for most of us, the answer is yes

Discovery that protein CD38 interrupts an interaction between the AIDS virus and its point of entry into cells

Possible new target for treating obesity and diabetes

Injury prevention could save Maryland at least $700 million per year

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