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Role of soft drinks in childhood obesity

Obesity is one of the biggest threats to child health. Genetics, decreases in physical activity, increases in television watching, and consumption of fast food are factors that have led to an increase of childhood obesity in the United States. Excessive consumption of sugar sweetened drinks may also be a key factor.

11 May 2005

Discovery may pave way for immunotherapies for prostate cancer

Using a common chemotherapy agent, researchers at UCLA's Jonsson Cancer Center and the Department of Pathology and Laboratory Medicine found a way to move an important biomarker expressed in prostate cancer, shaking it loose from one location in a cell – where it could not be accessed by blood – to another, easier to target area.

11 May 2005

Drug lowers inflammatory markers associated with risk for heart attack

A preliminary study suggests that use of a drug that inhibits a specific protein in patients with certain genetic variants that increase their risk for heart attack reduced their levels of inflammatory markers associated with heart attack risk, according to a study in the May 11 issue of JAMA.

10 May 2005

Broken bones may reduce risk of ovarian cancer

The pain and suffering of a broken bone may yield an unexpected benefit – a reduced risk of ovarian cancer.

10 May 2005

Research offers new molecular approaches to therapies for the most deadly cancers

Researchers at Wake Forest University Baptist Medical Center have found promising new molecular targets and treatment approaches for some of the most malignant brain tumors.

10 May 2005

Cytogen Corporation and Dowpharma collaborate to create a targeted oncology product designed to treat prostate and other cancers

Under the agreement, Dowpharma's proprietary MeO-DOTA bifunctional chelant technology will be used to radiolabel Cytogen's prostate-specific membrane antigen (PSMA) antibody with a therapeutic radionuclide. PSMA is a protein highly expressed on the surface of prostate cancer cells and the neovasculature of many solid tumors.

10 May 2005

Laboratory model of immune system overcomes ethical constraints on studies of hematopoietic stem cells in humans

Scientists at St. Jude Children’s Research Hospital have joined with colleagues at several other institutions to develop a laboratory model of the human immune system. This model will allow scientists to study ways for improving the results of hematopoietic stem cell (HSC) transplantation without putting patients at risk.

10 May 2005

A new approach to prevent cancer

Researchers at the University of Dundee have identified a way of inactivating a naturally occurring human protein, a development which could offer new routes to developing cancer prevention treatments.

10 May 2005

Cataract treatment in the blink of an eye

Researchers at the University of Canterbury, New Zealand are pioneering the development of an eye drop to halt the development of cataracts.

10 May 2005

New study suggests Pioglitazone HCl may significantly improve key predictors of cardiovascular risk

Study results published in the May 17th issue of Circulation, the journal of the American Heart Association, found that the diabetes medication pioglitazone HCl reduced carotid artery intima-media thickness (IMT). Patients taking pioglitazone also experienced significant reductions in insulin resistance, C-reactive protein (a marker for inflammation) and blood pressure, all of which contribute to the overall risk for cardiovascular disease.

9 May 2005

Many lives may be saved by new blood test for ovarian cancer

A new blood test which has the potential to save many lives has been developed to detect ovarian cancer, a disease known as the silent killer because it is so difficult to identify.

9 May 2005

New fat is needed to clear old fat from the system

Where fat comes from determines whether the body can metabolize it effectively. Researchers at Washington University School of Medicine in St. Louis have found that the "old" fat stored in the body's peripheral tissues -- that is, around the belly, thighs or bottom -- can't be burned efficiently unless "new" fat is eaten in the diet or made in the liver.

9 May 2005

Blood tests show autistic children have abnormal immune-system responses

Scientists in the U.S. have discovered that children with autism have abnormal immune-system responses and are optimistic that their findings could be used to develop a blood test to screen for the behavioural disorder.

9 May 2005

New treatment improves visual acuity score of patients with retinitis pigmentosa

Neurotech SA announced positive results from an open-label Phase I clinical trial (03-EI-0234) of its lead product, NT-501. NT-501 uses Neurotech’s patented Encapsulated Cell Technology (ECT) as a device to deliver ciliary neurotrophic factor (CNTF) to eyes of visually impaired patients with retinitis pigmentosa (RP). Neurotech is a biotechnology company specializing in the development of novel therapeutics to treat diseases of the eye. The company is headquartered in Paris.

8 May 2005

Researchers identify new areas of gene regulation

Researcher Kangling Zhang at the University of California, Riverside is part of a team that has discovered a new way that yeast governs genetic expression and repression, a finding that could be repeated in cells of other organisms.

8 May 2005

Simple and efficient method for creation of novel protein functions in an existing protein scaffold

By designing a molecular bridge, scientists at the University of Illinois at Urbana-Champaign have forged a successful pathway through a complex ocean of barriers: They've changed the function of a protein using a co-evolution approach.

8 May 2005

Researchers develop promising new gene network analysis method

Compared with a long-used linear model, a correlation-based statistical method is a more reliable way to map complex gene interactions and pinpoint genes that may be potential cancer treatment targets, according to new Brown University research.

8 May 2005

Promising new molecular targets and treatment approaches for some of the most malignant brain tumors

The first study identified a protein that seems to control the malignant features of brain tumor cells, suggesting a new treatment target for anti-cancer drugs. Researchers found that a little-known protein called Fra-1 was effective in controlling vascular endothelial growth factor D, a factor that promotes the growth of new blood vessels in most malignant brain tumors.

8 May 2005

Suspect gene may increase susceptibility to anxiety and depression

People with the depression-linked gene variant showed less gray matter and weaker connections in the mood-regulating circuit. How well the circuit was connected accounted for nearly 30 percent of their anxious temperament

8 May 2005

GM mice live longer and give hope for anti-aging treatments

U.S. scientists have produced genetically modified mice that live 20 per cent longer than normal and may have possibly discovered an approach to extending the human lifespan.

8 May 2005

G Protein News and Research

Role of soft drinks in childhood obesity

Discovery may pave way for immunotherapies for prostate cancer

Drug lowers inflammatory markers associated with risk for heart attack

Broken bones may reduce risk of ovarian cancer

Research offers new molecular approaches to therapies for the most deadly cancers

Cytogen Corporation and Dowpharma collaborate to create a targeted oncology product designed to treat prostate and other cancers

Laboratory model of immune system overcomes ethical constraints on studies of hematopoietic stem cells in humans

A new approach to prevent cancer

Cataract treatment in the blink of an eye

New study suggests Pioglitazone HCl may significantly improve key predictors of cardiovascular risk

Many lives may be saved by new blood test for ovarian cancer

New fat is needed to clear old fat from the system

Blood tests show autistic children have abnormal immune-system responses

New treatment improves visual acuity score of patients with retinitis pigmentosa

Researchers identify new areas of gene regulation

Simple and efficient method for creation of novel protein functions in an existing protein scaffold

Researchers develop promising new gene network analysis method

Promising new molecular targets and treatment approaches for some of the most malignant brain tumors

Suspect gene may increase susceptibility to anxiety and depression

GM mice live longer and give hope for anti-aging treatments

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