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Best treatment for the immobilizing trauma of spinal cord compression in metastatic cancer

In this week's Lancet, Patchell's UK research team evaluate traditional surgical and radiation therapy options and conclude that direct decompressive surgery plus postoperative radiotherapy is more effective than either radiotherapy alone or other surgical options.

22 Aug 2005

A cell's energy level is critical to its survival

In an ongoing effort to fight disease by manipulating energy regulation of cells, a collaborative study led by Dartmouth Medical School (DMS) has demonstrated that cells lacking a tumor-suppressing kinase called LKB1 can still maintain healthy energy levels when they become stressed.

22 Aug 2005

Non-invasive imaging may help predict type 1 diabetes and response to treatment in humans

A key obstacle to early detection of type 1 diabetes - as well as to rapid assessment of the effectiveness of therapeutic intervention - has been the lack of direct, non-invasive technologies to visualize inflammation in the pancreas, an early manifestation of disease.

22 Aug 2005

Newl workplace safety models

Tools for assisting organizations in their efforts to more accurately calculate, analyze, interpret and communicate the costs and benefits of workplace safety and health programs are featured as part of published proceedings released on July 29th in the National Safety Council's Journal of Safety Research (JSR).

22 Aug 2005

First proof of how the rare disorder Fanconi anemia causes chromosomal instability

The scientists found a gene mutation not previously known to be related to Fanconi anemia, and they say that BRIP1 is the first gene associated with the disease whose protein has a known function.

22 Aug 2005

New method to predict protein separation behavior directly from protein structure

Applying math and computers to the drug-discovery process, researchers at Rensselaer Polytechnic Institute have developed a method to predict protein separation behavior directly from protein structure.

22 Aug 2005

Butterbur extract should be considered as an alternative treatment for hayfever

The largest trial so far conducted using Butterbur extract to treat intermittent allergic rhinitis (hay fever) shows that this plant extract is as effective as a commonly used antihistamine (Telfast 180).

22 Aug 2005

Medulloblastoma irradiation may impair reading skills in young children

Irradiation therapy for the brain cancer medulloblastoma is more likely to impair IQ and reading skills of younger children than older children even if the dose of radiation is reduced, according to the results of the largest study of its kind, conducted by investigators at St. Jude Children's Research Hospital, Texas Children's Cancer Center (Houston) and Royal Children's Hospital (Melbourne, Australia).

22 Aug 2005

Detailed picture of migraines

Every eight adult Swede suffers from migraine. Using a new method, researchers at Göteborg have managed for the first time ever to provide a detailed picture of an untreated attack. This will be of great significance for the development of new forms of treatment.

22 Aug 2005

New phenomenon in which one bacterial cell can stop the growth of another on physical contact

Scientists have discovered a new phenomenon in which one bacterial cell can stop the growth of another on physical contact. The bacteria that stop growing may go into a dormant state, rather than dying. The findings have implications for management of chronic diseases, such as urinary tract infections.

22 Aug 2005

Increasing sugar processing in the liver may lead to future treatments for diabetes, obesity

Researchers at the University of Minnesota have shown that increasing the concentration of a key regulator involved in glucose metabolism can improve the way the liver produces and disposes of the sugar glucose, the primary fuel of the body. Finding ways to increase that concentration could provide a treatment for diabetes and obesity.

22 Aug 2005

Phase I cancer findings under-reported

Phase I cancer studies, trials that are conducted to determine the safety and maximum dose of a new agent, are under-reported in peer-reviewed journals - a trend that could ultimately delay scientific progress and negatively affect patient care, say researchers at The University of Texas M. D. Anderson Cancer Center in a new study out today (Mon., Aug, 22) online in Cancer.

22 Aug 2005

Cancer Research Technology licenses novel cancer diagnostic markers

Cancer Research Technology Limited announced today that they have entered into a worldwide license agreement with TriPath Imaging, Inc.

22 Aug 2005

Children who eat fries raise their risk of breast cancer later in life

According to a new study very young children who eat french fries frequently have a much higher risk of breast cancer as adults.

21 Aug 2005

Losing weight cuts breast cancer risk

An international team of scientists has found that young women who carry a breast cancer gene, can reduce their risk of the disease by up to 65% by attaining a healthy bodyweight.

21 Aug 2005

SH2-B enhances brain's leptin sensitivity - may lead to clues for treatment of obesity and diabetes

What do laboratory mice at the University of Michigan Medical School have in common with millions of overweight Americans? Like many of us, these mice just can't stop eating.

18 Aug 2005

High rate of heart attack amongst ethnic minorities in Scotland

The incidence of heart attack amongst Scots of Indian and Pakistani origin is 60-70% higher when compared with non-South Asians, a new report led by the University of Edinburgh has shown.

18 Aug 2005

Protein Sirt1 points to new therapies for type 2 diabetes

Opening the possibility of new therapies for type 2 diabetes, researchers at Washington University School of Medicine in St. Louis have found that a protein called Sirt1 enhances the secretion of insulin in mice and allows them to better control blood glucose levels. Their study appears in the August 17 issue of Cell Metabolism.

18 Aug 2005

Defects in newly discovered pathway may be an overlooked cause of anemia

Researchers studying zebrafish that die from anemia have discovered a new pathway for the synthesis of heme, the deep red, iron-containing molecule that is a component of hemoglobin and myoglobin.

18 Aug 2005

Anxiety disorders can compromise success of alcohol-dependence treatment

Individuals who have an anxiety disorder when starting treatment for alcohol dependence have a significantly greater risk for relapse to drinking within four months, according to researchers at the University of Minnesota.

18 Aug 2005

Research News and Research

Best treatment for the immobilizing trauma of spinal cord compression in metastatic cancer

A cell's energy level is critical to its survival

Non-invasive imaging may help predict type 1 diabetes and response to treatment in humans

Newl workplace safety models

First proof of how the rare disorder Fanconi anemia causes chromosomal instability

New method to predict protein separation behavior directly from protein structure

Butterbur extract should be considered as an alternative treatment for hayfever

Medulloblastoma irradiation may impair reading skills in young children

Detailed picture of migraines

New phenomenon in which one bacterial cell can stop the growth of another on physical contact

Increasing sugar processing in the liver may lead to future treatments for diabetes, obesity

Phase I cancer findings under-reported

Cancer Research Technology licenses novel cancer diagnostic markers

Children who eat fries raise their risk of breast cancer later in life

Losing weight cuts breast cancer risk

SH2-B enhances brain's leptin sensitivity - may lead to clues for treatment of obesity and diabetes

High rate of heart attack amongst ethnic minorities in Scotland

Protein Sirt1 points to new therapies for type 2 diabetes

Defects in newly discovered pathway may be an overlooked cause of anemia

Anxiety disorders can compromise success of alcohol-dependence treatment

New Approach Methodologies, the 3Rs and Multimodal Imaging in Preclinical Research - eBook eBook

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