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Ethnicity makes little difference in the quality of outpatient care

A new study from the Stanford University School of Medicine has found that once U.S. patients visit a doctor for outpatient care, their race and ethnicity make little difference in the quality of care they receive.

28 Jun 2005

New candidate for a vaccine against Lassa fever

Among the family of viral hemorrhagic fevers (which includes those caused by the Ebola, Marburg, and Hanta viruses), Lassa fever is the biggest public health problem.

28 Jun 2005

Adult, or post-natal, stem cells have the same ability as embryonic stem cells to multiply

In a ground-breaking study, scientists at Children's Hospital of Pittsburgh have discovered that adult, or post-natal, stem cells have the same ability as embryonic stem cells to multiply, a previously unknown characteristic indicating that post-natal stem cells may play an important therapeutic role.

27 Jun 2005

Scientists have discovered how C-reactive protein is able to access endothelial cells

For the first time, scientists have discovered how C-reactive protein, or CRP, is able to access endothelial cells. The UC Davis researchers' findings will be published in the July issue of Arteriosclerosis, Thrombosis, and Vascular Biology, one of the American Heart Association's leading journals.

27 Jun 2005

Pregnancy and birth factors may determine likelihood of polycystic ovarian syndrome

New research suggests that the way baby girls develop in the womb may affect whether or not they develop polycystic ovarian syndrome (PCOS) as adults and the severity of the symptoms if they do.

27 Jun 2005

Gleevec or similar drugs might be useful in preventing adverse side effects of smallpox vaccine

Mice given a relatively new cancer drug can survive an otherwise lethal dose of vaccinia virus, a relative of smallpox virus, report scientists supported by the National Institute of Allergy and Infectious Diseases (NIAID).

27 Jun 2005

Study causes big shift in how we think about p53 gene

The cellular cascade of molecular signals that instructs cells with fatally damaged DNA to self-destruct pivots on the p53 tumor suppressor gene. If p53 is inactivated, as it is in over half of all human cancers, checks and balances on cell growth fail to operate, and body cells start to accumulate mutations, which ultimately may lead to cancer.

27 Jun 2005

Scientists solve structure of a critical innate immune system protein

Scientists at The Scripps Research Institute have solved the structure of a crucial human immune system molecule called TLR3, an acronym for Toll-like receptor three. In an upcoming issue of the journal Science, the protein is described as a large horseshoe-shaped coil composed of 23 leucine-rich repeats (LRRs).

27 Jun 2005

Researchers successfully treat laboratory model of a lysosomal storage disease called GM1

Physicians might one day be able to treat a disease that destroys brain cells in children using genetically modified cells to transport a "drug" to the site of the dying neural cells (cells that transmit impulses).

27 Jun 2005

Triplet pregnancies cost more than eight times as much as singleton pregnancies

Research in France has revealed that triplet pregnancies cost more than eight times as much as singleton pregnancies, and twin pregnancies cost more than three times as much, the 21st annual conference of the European Society of Human Reproduction and Embryology heard.

27 Jun 2005

If you know how viruses get into cells, you know how to better design drugs to keep them out

When it comes to gaining entry into cells, size matters. A team from Brown University and the Max Planck Institute for Metals Research has created a model that explains how viruses and other bioparticles slip inside cells without a special protein coating called clathrin.

27 Jun 2005

Health, well-being, and aging in Latin America and the Caribbean

The demographics of aging in the Americas are well known. The United Nations has published projections showing that by the middle of this century, Latin America and the Caribbean will have 112 persons 60 years and older for every 100 persons 15 or under. North America will have 148 older persons for every 100 persons 15 or younger. While those numbers are impressive, the phenomenon itself represents more than just numbers.

27 Jun 2005

Simple analysis of a bone marrow transplant patient's oral rinse indicates whether infection will develop

Simple analysis of a bone marrow transplant patient's oral rinse can give medical personnel a quick indication of the transplant's effectiveness and predict whether an infection will develop, says a University of Toronto researcher.

27 Jun 2005

Scientists successfully isolate stem cells from human skin

Scientists at Wake Forest University School of Medicine have successfully isolated stem cells from human skin, expanded them in the laboratory and coaxed them into becoming fat, muscle and bone cells.

27 Jun 2005

Brief course of chemotherapy after surgery should be the new standard of care around the world

A Canadian national clinical trial has found that chemotherapy following surgery for early-stage non-small cell lung cancer significantly improves survival for the disease over just surgery alone.

27 Jun 2005

Breast cancer growth regulator sEGFR holds promise for more targeted treatment

Researchers at Yale School of Medicine have discovered the breast cancer growth regulator sEGFR, which may be a useful tool in monitoring a patient's responsiveness to treatment with the drug letrozole.

27 Jun 2005

Enzyme known as cathepsin G may be a target for anti-inflammatory treatments

The finding by researchers at Washington University School of Medicine in St. Louis shows that an enzyme known as cathepsin G regulates the ability of immune cells known as neutrophils to secrete chemicals that attract other immune cells and start the local inflammatory process. Over time, the excessive accumulation of immune cells can lead to tissue and cartilage damage in joints, causing pain and limiting mobility.

27 Jun 2005

Tricirbine may help fight cancers

H. Lee Moffitt Cancer Center & Research Institute, working in partnership with the University of South Florida (USF), has discovered a new use for an old, previously discredited anti-cancer drug that could add another weapon in the arsenal against several cancers, including tumors of the breast, ovary, colon, skin and prostate.

27 Jun 2005

Light used to regulate protein synthesis

Proteins are the puzzle-pieces of life, involved in how organisms grow and flourish, but studying their complex biological processes in living systems has been extremely difficult.

27 Jun 2005

Technique called phylogenetic footprinting reveals new gene regulation system

By comparing 140 sequenced bacterial genomes, researchers have uncovered a system for regulating genes essential to bacterial replication - and they did it solely by computer keystrokes and mouse clicks.

27 Jun 2005

Research News and Research

Ethnicity makes little difference in the quality of outpatient care

New candidate for a vaccine against Lassa fever

Adult, or post-natal, stem cells have the same ability as embryonic stem cells to multiply

Scientists have discovered how C-reactive protein is able to access endothelial cells

Pregnancy and birth factors may determine likelihood of polycystic ovarian syndrome

Gleevec or similar drugs might be useful in preventing adverse side effects of smallpox vaccine

Study causes big shift in how we think about p53 gene

Scientists solve structure of a critical innate immune system protein

Researchers successfully treat laboratory model of a lysosomal storage disease called GM1

Triplet pregnancies cost more than eight times as much as singleton pregnancies

If you know how viruses get into cells, you know how to better design drugs to keep them out

Health, well-being, and aging in Latin America and the Caribbean

Simple analysis of a bone marrow transplant patient's oral rinse indicates whether infection will develop

Scientists successfully isolate stem cells from human skin

Brief course of chemotherapy after surgery should be the new standard of care around the world

Breast cancer growth regulator sEGFR holds promise for more targeted treatment

Enzyme known as cathepsin G may be a target for anti-inflammatory treatments

Tricirbine may help fight cancers

Light used to regulate protein synthesis

Technique called phylogenetic footprinting reveals new gene regulation system

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