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First clues as to why stem cells ignore stop signs in the cell cycle

Everyone knows that stem cells are controversial. Many people know that stem cells can grow into virtually any cell type found in the body, from a red blood cell to a muscle cell to a brain cell. But no one really knows why stem cells continue to divide and renew themselves long after the point where other cells stop dividing.

10 Jun 2005

Finding could provide targets for diagnosis, prognosis, therapy of prostate cancer

Researchers led by Dr. Shiv Srivastava from the Center for Prostate Disease Research (CPDR), Uniformed Services University of the Health Sciences (USU), report the groundbreaking discovery of the ETS-Related Gene (ERG) as one of the frequent proto-oncogene overexpressions in prostate cancer cells.

10 Jun 2005

Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance

Using targeted RNA interference, or RNAi libraries, researchers at Harvard Medical School describe the first large-scale classification of kinase and phosphatase gene families on the basis of their role in apoptosis and cell survival. This study appears in the June issue of Nature Cell Biology.

10 Jun 2005

Claritin's switch to OTC status meant fewer prescriptions

After the allergy drug Claritin became available without a prescription in 2002, insurance plans and consumers spent less on the prescription form of its main ingredient, loratadine, and all similar allergy drugs, according to a new report published in this month’s The American Journal of Managed Care.

10 Jun 2005

European approval of Temodal (temozolomide) capsules for treatment of glioblastoma multiforme

Schering-Plough announced today that the European Commission has granted approval of Temodal (temozolomide) Capsules for first-line use for the treatment of patients with newly diagnosed glioblastoma multiforme (GBM), the most common and aggressive form of primary brain cancer.

10 Jun 2005

Brain shrinkage appears to have no impact on an individual's capacity to think or learn

The research is part of a 20-year study by the ANU Centre for Mental Health Research called PATH Through Life and suggests a revision of long-standing views on the impact of age-related brain shrinkage.

10 Jun 2005

No significant long-term benefit in administering immediate treatment to those with early epilepsy

Around 500,000 people in the UK suffer from epilepsy, making it the most common serious neurological condition. Many of those who develop epilepsy start having seizures during childhood, but it can develop at any age.

10 Jun 2005

AIDS expert says global strategy needed to combat feminization of HIV/AIDS

Thomas C. Quinn, M.D., a Johns Hopkins physician and scientist, who has spent the best part of the last 25 years leading major efforts to combat HIV and AIDS throughout the world, is calling for global strategies and resources to confront the rapid "feminization" of the AIDS pandemic.

10 Jun 2005

DNA discovery may help explain disorders such as autism

Researchers have made a discovery that may in future help to explain many aspects of human social behavior and disorders such as autism.

10 Jun 2005

Digital mammography no better than traditional film X-rays in the ability to detect cases of breast cancer

Digital mammography provides no clear-cut improvements over traditional film X-rays in the ability to detect cases of breast cancer, says a new technology assessment report. The technology does, however, offer other benefits, including slightly lower radiation doses for patients, that may prompt its increasing use despite its much higher costs.

10 Jun 2005

Exercise helps recovery after chemotherapy for breast cancer

Exercise after chemotherapy for breast cancer boosted the activity of infection-fighting T cells in women who worked out regularly, according to data from a study conducted at Penn State University under the direction of Andrea Mastro, professor of microbiology and cell biology.

10 Jun 2005

Researchers discover how hepatic-C virus evades immune system in acute and chronic infections

Researchers at Johns Hopkins have uncovered how a majority of the genetic changes in the hepatic-C virus, the most common cause of liver disease, allow it to evade the body's immune system during infection.

10 Jun 2005

Urgent call for global strategies and resources to confront the rapid "feminization" of the AIDS pandemic

In an article appearing in the journal Science online June 10, Thomas C. Quinn, M.D., professor of infectious diseases at Hopkins and a senior investigator at the National Institute of Allergy and Infectious Disease, reports that women have in the last 20 years moved from those least affected by HIV to those in whom the disease is spreading fastest.

10 Jun 2005

Study sheds light on endometriosis pain

Women with endometriosis often have several types of chronic pain conditions because their abnormal growths develop a nerve supply that communicates with the brain, new research suggests.

10 Jun 2005

Researchers explain how ubiquitin function is determined

University of Maryland researchers have explained, for the first time, why the linkage between the cell-regulating protein molecules called ubiquitins determines their function.

10 Jun 2005

Findings could lead to a new approach in diagnosing and treating Alzheimer’s disease

The human body has its own defense against brain aging: the innate immune system, which helps to clean the brain of amyloid-beta waste products. However, UCLA researchers discovered that some patients with Alzheimer’s disease have an immune defect making it difficult to clean away these wastes.

From MP Biomedicals, LLC 10 Jun 2005

Unique therapeutic strategy to combat cachexia

Researchers at Oregon Health & Science University's Doernbecher Children's Hospital have uncovered a unique therapeutic strategy to combat cachexia - severe malnutrition and physical wasting away - in children and adults with chronic kidney disease (CKD). The study is published in the June issue of the Journal of Clinical Investigation.

9 Jun 2005

Information to guide child health policy is lacking in the poorest countries with the highest rates of childhood mortality

Around 10.8 million children die worldwide each year. Credible global and national estimates of the burden of disease in childhood are essential for the development of appropriate health policy and implementation of health interventions to prevent these deaths.

9 Jun 2005

Scientists produce for the first time an infectious form of the hepatitis C virus in laboratory cultures of human cells

The finding, reported in the June 9 issue of Science Express, will allow scientists to study every stage of the HCV life cycle and develop drugs to treat this life-threatening disease that affects more than 170 million people around the world.

9 Jun 2005

Experimental drug works best in combination with older remedy for Alzheimer's disease and other dementias

An experimental drug combined with an already-popular memory-enhancing compound may further delay memory loss in patients with Alzheimer's disease and other dementias, Johns Hopkins University scientists, in collaboration with researchers from University of North Carolina, have found.

9 Jun 2005

Research News and Research

First clues as to why stem cells ignore stop signs in the cell cycle

Finding could provide targets for diagnosis, prognosis, therapy of prostate cancer

Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance

Claritin's switch to OTC status meant fewer prescriptions

European approval of Temodal (temozolomide) capsules for treatment of glioblastoma multiforme

Brain shrinkage appears to have no impact on an individual's capacity to think or learn

No significant long-term benefit in administering immediate treatment to those with early epilepsy

AIDS expert says global strategy needed to combat feminization of HIV/AIDS

DNA discovery may help explain disorders such as autism

Digital mammography no better than traditional film X-rays in the ability to detect cases of breast cancer

Exercise helps recovery after chemotherapy for breast cancer

Researchers discover how hepatic-C virus evades immune system in acute and chronic infections

Urgent call for global strategies and resources to confront the rapid "feminization" of the AIDS pandemic

Study sheds light on endometriosis pain

Researchers explain how ubiquitin function is determined

Findings could lead to a new approach in diagnosing and treating Alzheimer’s disease

Unique therapeutic strategy to combat cachexia

Information to guide child health policy is lacking in the poorest countries with the highest rates of childhood mortality

Scientists produce for the first time an infectious form of the hepatitis C virus in laboratory cultures of human cells

Experimental drug works best in combination with older remedy for Alzheimer's disease and other dementias

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