G Protein News and Research

RSS

TSRI researchers find way to switch off urge for compulsive drinking in rat models

There may be a way to switch off the urge for compulsive drinking, according to a new study in animal models led by scientists at The Scripps Research Institute.

6 Sep 2016

New drug holds potential for treating advanced mastocytosis

Most people have never heard of mastocytosis. It's a rare, sometimes deadly, immune disorder. Now new research may help those with advanced mastocytosis and possibly many more people, too.

6 Sep 2016

TUM researchers use luminous jellyfish proteins to investigate cardiac rhythm dysfunctions

Cell models from stem cells serve an ever-increasing role in research of cardiac dysfunction. Researchers at the Technical University of Munich have succeeded in producing cells which offer new insights into properties of the heart.

6 Sep 2016

Caltech scientists uncover three-dimensional structure of disease-fighting protein

The polymeric immunoglobulin receptor, or pIgR, is a multitasking protein produced in the lining of mucosal surfaces, such as the intestines. It plays a pivotal role in the body's immune functions by sequestering bacteria and by assisting antibodies—large proteins that can identify and neutralize specific bacteria and viruses.

6 Sep 2016

Researchers identify potential new way of treating hypertension

Researchers eyeing first new anti-hypertensive drug treatment strategy in more than 15 years.

6 Sep 2016

Experimental co-culture approach facilitates study of cellular events underlying Huntington's disease

Using an experimental co-culture approach in which two different types of neurons from a mouse model of Huntington's disease (HD) are grown side-by-side, connecting to form critically impacted circuits, researchers at University of California San Diego School of Medicine have identified a subunit of a protein that, when expressed, reverse the mutated gene effects responsible for HD.

6 Sep 2016

Researchers use unique computational approach to identify promising drug leads for heart diseases

Using a unique computational approach to rapidly sample, in millisecond time intervals, proteins in their natural state of gyrating, bobbing, and weaving, a research team from UC San Diego and Monash University in Australia has identified promising drug leads that may selectively combat heart disease, from arrhythmias to cardiac failure.

6 Sep 2016

HIF-2 inhibitors could be promising target to combat kidney cancer

A new class of drugs called HIF-2 inhibitors is more effective and better tolerated than the standard of care drug sunitinib in treating kidney cancer, researchers with the Kidney Cancer Program at Harold C. Simmons Comprehensive Cancer Center have found.

6 Sep 2016

Researchers describe how genetic mutations cause unnamed neurological disorder

In rare cases -- for instance, among siblings in two families from Pakistan and Oman described in a new study -- children have been born with an unnamed neurological disorder.

6 Sep 2016

Novel technique offers new insights into growth variation across single cells

A new technique invented at MIT can precisely measure the growth of many individual cells simultaneously.

5 Sep 2016

New discovery offers way to develop vaccine against highly infectious bacteria

Biochemists at the University of California San Diego have uncovered patterns in the outer protein coat of group A Streptococcus that could finally lead to a vaccine against this highly infectious bacteria--responsible for more than 500,000 deaths a year, including toxic shock syndrome and necrotizing fasciitis or "flesh-eating disease."

5 Sep 2016

Biobank blood storage time may influence test results, study finds

The amount of time a blood sample used for medical research has been stored at a biobank may affect the test results as much as the blood sample provider's age.

5 Sep 2016

Researchers identify epigenetic mechanism causing aberrancies in coeliac disease

Researchers at the University of Tampere discovered a mechanism causing aberrancies in coeliac disease and colorectal cancer.

5 Sep 2016

DNA-binding protein CHD1 could be potential biomarker for targeted prostate cancer treatment

The loss of CHD1, one of the most frequently mutated genes in prostate tumors, sensitizes human prostate cancer cells to different drugs, including PARP inhibitors.

5 Sep 2016

JMU scientists crystallize new inhibitory antibodies targeting sclerostin

Osteoporosis particularly affects elderly women: the bone's structure weakens and the risk of suffering fractures rises.

2 Sep 2016

Discovery of signalling pathway could pave way for developing treatments targeting T-ALL leukaemia

Cooperation between Finnish and Chinese research groups has opened up new opportunities for developing treatments targeting aggressive acute lymphoblastic leukaemia (T-ALL).

2 Sep 2016

NanoTemper Technologies employs game-changing solutions for faster drug development

Following a successful inaugural meeting in 2014, the 2nd Drug Discovery Forum (DDF) took place on May 8–11, 2016 at the Westin Grand Hotel in Munich.

From NanoTemper Technologies 2 Sep 2016

NanoTemper Technologies to highlight applications of MST, nanoDSF in drug discovery at Biopharma Workshop 2016

NanoTemper Technologies offers MicroScale Thermophoresis (MST) and nanoDSF technology to analyze these parameters in an easy and precise way. To meet the increasing demand for high-throughput applications and unattended operation, NanoTemper Technologies provides fully automated MST and nanoDSF platforms — and combinations of both.

From NanoTemper Technologies 2 Sep 2016

Researchers uncover molecular differences between African and Asian strain of Zika virus infections

Scientists have revealed molecular differences between how the African and Asian strains of Zika virus infect neural progenitor cells.

1 Sep 2016

Low levels of diastolic blood pressure linked to heart damage risk

By analyzing medical records gathered over three decades on more than 11,000 Americans participating in a federally funded study, researchers at Johns Hopkins Medicine say they have more evidence that driving diastolic blood pressure too low is associated with damage to heart tissue.

1 Sep 2016

G Protein News and Research

TSRI researchers find way to switch off urge for compulsive drinking in rat models

New drug holds potential for treating advanced mastocytosis

TUM researchers use luminous jellyfish proteins to investigate cardiac rhythm dysfunctions

Caltech scientists uncover three-dimensional structure of disease-fighting protein

Researchers identify potential new way of treating hypertension

Experimental co-culture approach facilitates study of cellular events underlying Huntington's disease

Researchers use unique computational approach to identify promising drug leads for heart diseases

HIF-2 inhibitors could be promising target to combat kidney cancer

Researchers describe how genetic mutations cause unnamed neurological disorder

Novel technique offers new insights into growth variation across single cells

New discovery offers way to develop vaccine against highly infectious bacteria

Biobank blood storage time may influence test results, study finds

Researchers identify epigenetic mechanism causing aberrancies in coeliac disease

DNA-binding protein CHD1 could be potential biomarker for targeted prostate cancer treatment

JMU scientists crystallize new inhibitory antibodies targeting sclerostin

Discovery of signalling pathway could pave way for developing treatments targeting T-ALL leukaemia

NanoTemper Technologies employs game-changing solutions for faster drug development

NanoTemper Technologies to highlight applications of MST, nanoDSF in drug discovery at Biopharma Workshop 2016

Researchers uncover molecular differences between African and Asian strain of Zika virus infections

Low levels of diastolic blood pressure linked to heart damage risk

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer

Latest News