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Largest "gene deserts" yet discovered in the human genome sequence

A detailed analysis of chromosomes 2 and 4 has detected the largest "gene deserts" known in the human genome and uncovered more evidence that human chromosome 2 arose from the fusion of two ancestral ape chromosomes, researchers supported by the National Human Genome Research Institute (NHGRI).

6 Apr 2005

Genetic testing could bolster radiotherapy's effectiveness against cancer

Obtaining a genetic picture of how a tumor will react to the many treatment techniques available could help doctors prescribe therapies customized for individual cancer patients' needs, suggests a Purdue University research team.

5 Apr 2005

Potential therapeutic target for infertility and contraception

The multiple “litter” births of mice, versus the normal singleton pregnancy of humans, is due to defective processing in mice of a common mammalian protein called bone morphogenetic protein 15 (BMP-15), according to new research from the University of California, San Diego (UCSD) School of Medicine.

5 Apr 2005

Dallas heart study researchers find no link between Lp(a), calcium

The latest findings from the historic Dallas Heart Study have ruled out one of the most prominent explanations of why elevated levels of a fat-carrying protein called "lipoprotein(a)" lead to increased risks for heart attacks among whites but not among African-Americans.

5 Apr 2005

Method of gene therapy accurately corrects mutations in disease-causing genes

Harnessing the strength of a natural process that repairs damage to the human genome, a researcher from UT Southwestern Medical Center has helped establish a method of gene therapy that can accurately and permanently correct mutations in disease-causing genes.

5 Apr 2005

Genomics and proteomics to increase the efficiency of drug discovery and development

While the United Sates is still the world leader, Europe is having a good deal of success in the field of advanced genomics and proteomics research. Significant government funding together with the presence of large pharmaceutical companies has made Europe a major competitor in the efforts to deploy genomics and proteomics as vital tools in drug discovery and development.

5 Apr 2005

DNA repair kit announced by scientists

A study by scientists at Sangamo BioSciences, Inc. has demonstrated the use of the Company's zinc finger DNA-binding protein (ZFP) technology to achieve highly efficient, permanent correction of a disease-causing gene in primary human cells.

5 Apr 2005

An exceptionally effective lead-detection protein

Scientists from the U.S. Department of Energy’s Brookhaven National Laboratory and the University of Chicago have discovered that a member of a well-known protein family is better at detecting lead than any other known substance.

5 Apr 2005

Alteration of steroid receptor genes creates fat burning muscle

The Salk Institute scientist who earlier discovered that enhancing the function of a single protein produced a mouse with an innate resistance to weight gain and the ability to run a mile without stopping has found new evidence that this protein and a related protein play central roles in the body's complex journey to obesity and offer a new and specific metabolic approach to the treatment of obesity related disease such as Syndrome X (insulin resistance, hyperlipidemia and atherosclerosis).

4 Apr 2005

Certain combinations of genes increase the risk of developing cervical cancer

Certain combinations of genes that encode receptors on innate immune cells increase the risk of developing cervical cancer, according to a study by Mary Carrington and colleagues in the April 4 issue of The Journal of Experimental Medicine.

4 Apr 2005

Natural killer cells could lead to new Hepatitis treatments

Researchers have discovered that natural killer T (NKT) cells, the immune system's sentinels, patrol the labyrinthine blood vessels of the liver for invaders or signs of tissue damage and demonstrate a dogged behavior not seen before in other T cells.

4 Apr 2005

Immune cells in the liver travel in the liver's blood vessels with surprising speed and agility

Scientists at New York University School of Medicine viewing the actual journey of immune cells in the liver have found that these cells travel in the liver's blood vessels with surprising speed and agility.

4 Apr 2005

Method of gene therapy that can accurately and permanently correct mutations in disease-causing genes

4 Apr 2005

Obesity may hinder body's ability to control influenza infection

Obesity apparently reduces laboratory mice’s ability to turn on elements of their immune systems needed for controlling influenza infection, a new University of North Carolina at Chapel Hill School of Medicine study shows.

4 Apr 2005

Bionic eyes from Stanford

Stanford physicists and eye doctors have teamed up to design a "bionic eye," of sorts. On Feb. 22 in the Journal of Neural Engineering, Daniel Palanker, Alexander Vankov and Phil Huie from the Department of Ophthalmology and the Hansen Experimental Physics Laboratory and Stephen Baccus from the Department of Neurobiology published a design of an optoelectronic retinal prosthesis system that can stimulate the retina with resolution corresponding to a visual acuity of 20/80

4 Apr 2005

Step toward a potential treatment for Huntington's disease

Researchers at the University of Iowa Roy J. and Lucille A. Carver College of Medicine have taken another step toward a potential treatment for Huntington's disease (HD). Using an approach called RNA interference (RNAi), the scientists reduced levels of the disease-causing HD protein in mice and significantly improved the movement and neurological abnormalities normally associated with the disease.

4 Apr 2005

Peanuts back in fashion!

The peanut, has made a comeback and consumption has soared to its highest level in nearly two decades with more and more doctors recommending the nuts as part of a heart-healthy diet.

4 Apr 2005

Scientists find how pneumonia bacteria get sugar boost to survive

Meningitis and pneumonia bacteria smash into our lungs and cells to steal sugar, which helps them survive, according to research presented from King's College and Guy's Hospital London, (Monday, 04 April 2005) at the Society for General Microbiology's 156th Meeting at Heriot-Watt University, Edinburgh.

4 Apr 2005

New chemicals to inhibit HIV infection

In corporation with peers from the Mount Sinai School of Medicine, New York University, researchers from the University of Science and Technology of China (USTC), a CAS affiliate, have come up with new chemical inhibitors against HIV reproduction, marking a significant progress in the development of anti-AIDS drugs based on natural host resistance.

4 Apr 2005