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Protein sequenced from 75,000 year old Iraqi

An international team led by researchers at the Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology in Liepzig, Germany and Washington University in St. Louis, has extracted and sequenced protein from a Neanderthal from Shanidar Cave, Iraq dating to approximately 75,000 years old.

9 Mar 2005

Telomerase finding has major implications for cancer

UCLA biochemists have determined the three-dimensional structure of a major domain of telomerase, the enzyme that helps maintain telomeres - small pieces of DNA on the ends of chromosomes that act as protective caps - allowing DNA ends to be copied completely when cells are replicated.

9 Mar 2005

Overlapping signals in embryo help get the backbone right

A major step in the development of the vertebrate embryo - the establishment of a back that morphs into a brain, spinal cord and muscles - turns out to be so important that the body uses at least three signals to make sure it happens properly.

9 Mar 2005

Infertility - discovery could mean new treatment

A team of Japanese scientists at Osaka University led by Dr Masaru Okabe have discovered a protein essential for human sperm to fuse to an egg. The findings could well lead to new methods of treating infertility and the development of new contraceptive strategies.

9 Mar 2005

Progress toward development of a breast cancer vaccine

Progress toward development of a breast cancer vaccine has been reported by researchers at Washington University School of Medicine and the Siteman Cancer Center in St. Louis.

8 Mar 2005

Biomedical engineers, chemists collaborate on novel method to design better medicines

The ability to select and develop compounds that act on specific cellular targets has just gained a computational ally -- a mathematical algorithm that predicts the precise effects a given compound will have on a cell's molecular components or chemical processes.

8 Mar 2005

NASA scientists find clues about kidney disease

NASA scientists and academic colleagues are studying tiny hairs inside microorganisms to find clues about kidney disease.

8 Mar 2005

New system for growing human embryonic stem cells could make therapies utilising the cells safer for patients

A new system for growing human embryonic stem cells could make therapies utilising the cells safer for patients, concludes a study published online by The Lancet (Tuesday, March 8, 2005).

8 Mar 2005

Protein circulating in the blood delivers selenium to germ cells, enabling normal development of sperm

A paper to be published in the journal Biology of Reproduction offers evidence that a protein circulating in the blood of mammals delivers the dietary micronutrient selenium to germ cells, enabling these cells to develop into normal sperm.

7 Mar 2005

Impaired insulin function may be behind some of the abnormalities found in Alzheimer's disease

A research team led by Dr Suzanne de la Monte and Dr. Jack Wands of the Brown University Medical School has found that impaired insulin function may be behind some of the abnormalities found in Alzheimer's disease (AD).

7 Mar 2005

Two chemicals boost immune cells' ability to fight HIV without gene therapy

A UCLA AIDS Institute study has discovered that two chemical compounds may help the immune systems of HIV-infected persons fight the disease without invasive gene therapy.

7 Mar 2005

ViroLogic and AstraZeneca to conduct Iressa biomarker study

ViroLogic announced today that it had entered into an agreement with AstraZeneca to conduct a cancer biomarker study with application to Iressa, AstraZeneca's selective epidermal growth factor receptor kinase inhibitor.

7 Mar 2005

Neuren and Metabolic collaborate to develop range of nerve repair compounds

Neuren Pharmaceuticals Ltd (Neuren) and Metabolic Pharmaceuticals Ltd (Metabolic) have announced that the two companies have agreed to collaborate to co-develop Neuren's class of Neuro-regenerative Peptides (NRPs) for the treatment of degenerative conditions such as peripheral neuropathy, motor neuron disease and repairing the brain or nerves after injuries such as spinal cord injury.

7 Mar 2005

Novel role for cholesterol inside the cell

Cholesterol, often condemned for its role in heart disease, has always been known to be essential for the health of the fatty membranes that surround individual cells.

7 Mar 2005

Good side to cholesterol in controlling cell signals

Cholesterol, often stigmatized for its role in heart disease, has long been known to be essential for the health of the fat-laden membranes that surround individual cells.

6 Mar 2005

First genetic marker to help identify ruptured brain aneurysm

Mayo Clinic researchers have discovered a genetic marker that may pave the way for a fast, inexpensive blood test to predict one type of deadly stroke that strikes 30,000 people in the United States annually.

6 Mar 2005

Definitive evidence that TRPV3 is a temperature sensor

The human brain is like a general in a bunker. Floating in its bubble of cerebrospinal fluid, it has no direct window to the outside world, so the only way for the brain to observe, comprehend, and order the body into action is to rely on information it receives.

6 Mar 2005

Scientists discover how substitutions are made for injured genes

If there were no bench for second-string players on a football team, who would substitute for tired or injured team members? A team of Weizmann Institute scientists has found that, if the team were made up of genes, they might pull athletes who can play a little football in a pinch from nearby basketball or rugby teams.

6 Mar 2005

New therapeutic targets in liver diseases

Many patients with liver diseases often encounter difficulties with therapy and ultimately require liver transplant to survive. Since many acute and chronic liver diseases are driven by immune-mediated mechanisms, there is a necessity to find new therapies that can inhibit these immune-based triggers and block liver damage.

6 Mar 2005

Clearance of beta amyloid accumulation within neurons stops memory decline

Researchers at UC Irvine have identified a trigger at the molecular level that marks the onset of memory decline in mice genetically engineered to develop brain lesions – in the form of plaques and tangles – associated with Alzheimer's disease.

6 Mar 2005