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African genome research given impetus

Millions of victims in Africa, die each year from preventable diseases like tuberculosis and malaria and researchers say only a relatively small proportion of money is spent on developing vaccines, much more is spent on drugs aimed at tackling diseases more prevalent among rich, Western consumers.

21 Mar 2005

African-American women with advanced endometrial cancer have more aggressive tumors than Caucasian women

In two studies of African-American women with endometrial cancer, a group of investigators from Walter Reed Army Medical Center and the National Cancer Institute has found that African-American women with advanced endometrial cancer have more aggressive tumors than Caucasian women, potentially leading to worse outcomes.

21 Mar 2005

New information on TB available online

A range of new information on TB including top facts and a handy Q&A will be available at the click of a button when it goes live on www.immunisation.nhs.uk tomorrow - ahead of World Stop TB Day.

21 Mar 2005

Compound found in broccoli is a powerful disease fighter

More than 300 scientific studies point to an antioxidant found in broccoli sprouts, sulforaphane glucosinolate (SGS), as a factor in preventing multiple diseases, including several types of cancer, high blood pressure, macular degeneration and stomach ulcers.

21 Mar 2005

New study to evaluate Pegasys and Copegus to treat hepatitis C in liver transplant patients

Roche has initiated a new study to evaluate treatment strategies to reduce post-transplant recurrence of hepatitis C infection with the most prescribed hepatitis C treatment combination in the U.S., Pegasys (peginterferon alfa-2a) and Copegus (ribavirin, USP).

21 Mar 2005

Sports drinks can damage teeth

While sports and energy drinks help athletes re-hydrate after a long workout, if consumed on a regular basis they can damage teeth.

21 Mar 2005

Structure of key protein in innate immune response

In a report published in the Journal of Biological Chemistry, scientists in Korea announced their elucidation of three-dimensional structure of CD14 and showed how it is perfectly suited to bind to certain bacterial products.

21 Mar 2005

Oral hygiene during preschool years can mean a lifetime of good oral health

Providing proper care and oral hygiene during preschool years can mean a lifetime of good oral health, according to a recent article in the January/February issue of General Dentistry, clinical, peer-reviewed journal of the Academy of General Dentistry (AGD), an organization of general dentists dedicated to continuing education.

21 Mar 2005

Welfare reforms haven't helped poor children, study shows

Welfare reforms have made no substantial difference to the development of Canadian pre-school children living in poverty, according to a new University of Alberta study.

21 Mar 2005

New research in mice sheds light on the causes behind male infertility

For 40 percent of the estimated six million American couples battling infertility, the problem lies with the man. But help may be on the way.

21 Mar 2005

Hospitals may now be more willing to partner up with former adversaries

A study publishing in the latest issue of Health Services Research is one the few published evaluations of the Centers for Medicare and Medicaid Services Quality Improvement Organizations (QIO).

21 Mar 2005

Scientists provide insight into the molecular mechanisms behind Listeria monocytogenes

When the bacterium Listeria monocytogenes invades the body, it commandeers its host cell's actin cytoskeleton to invade other cells. In a report published in the Journal of Biological Chemistry, a group of scientists provide insight into the molecular mechanisms behind this infection technique.

21 Mar 2005

Invasive pneumonia and antibiotic resistance decreased after childhood streptococcus pneumoniae vaccine introduced

The problem of increasing antibiotic resistance in cases of Streptococcus pneumoniae, a major cause of pneumonia, meningitis and sepsis, was dramatically reversed following the licensing and use of a new conjugate vaccine for young children in February 2000, according to research conducted at Emory University, the Atlanta Veterans Affairs Medical Center, the Centers for Disease Control and Prevention, and the Georgia Division of Public Health.

21 Mar 2005

Waist size is better predictor of diabetes 2 risk than BMI

This finding, published in the March 2005 issue of the American Journal of Clinical Nutrition, is based on data collected from 27,270 men tracked over 13 years who participated in the Harvard Health Professionals Follow-Up Study.

21 Mar 2005

Calls to regionalize the care of patients with heart attacks are premature

Calls to regionalize the care of patients with heart attacks are premature, and do not account for potential unintended consequences, according to a commentary by Yale researchers published in the Journal of the American Medical Association (JAMA).

21 Mar 2005

Scientists find microRNA regulates Ras cancer gene

Research in the laboratory of Assistant Professor Frank J. Slack at Yale University has identified a new way that a familiar gene is regulated in lung cancer, presenting new possibilities for diagnosis and treatment. The work is reported in March issues of the journals Cell and Developmental Cell.

21 Mar 2005

MicroJet injector for painless injections

Parents know all too well the pain experienced by their children - and themselves - when the time comes for immunizations at the doctor's office.

21 Mar 2005

Genomic analysis may one day be a primary diagnostic tool for physicians deciding on a course of treatment for trauma

The researchers showed that state-of-the-art techniques for rapidly analyzing changes in activity of all human genes will likely produce useful insights into the health of critically ill patients. The findings, which are available online and will be published in the March 29 issue of the Proceedings of the National Academy of Sciences, make it possible for physicians to begin answering important questions about critical care through genomic analysis.

21 Mar 2005

Sixteen per cent of people who use cannabis for medical reasons say that their doctor suggested it

"The results of our UK survey, including the extent of use and reported effects, lend support to the further development of safe and effective medicines based on cannabis" says lead author Dr Mark Ware principal investigator and pain physician at the McGill University Health Centre (MUHC) Pain Centre.

21 Mar 2005

$3.2 million for two shock-related studies

A Virginia Commonwealth University research group has been awarded $3.2 million in federal grants for two shock-related studies, one with battlefield implications and the other for emergency medicine.

21 Mar 2005